(108 nodes) Negative regulation of small molecule metabolic process network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109990231	Uncharacterized protein. (251 aa)
	ENSLBEP00000001011	Uncharacterized protein. (252 aa)
	snai2	Snail family zinc finger 2. (260 aa)
	ENSLBEP00000001352	Uncharacterized protein. (251 aa)
	sirt6	Sirtuin 6. (351 aa)
	ENSLBEP00000001942	annotation not available (252 aa)
	ENSLBEP00000002292	Uncharacterized protein. (252 aa)
	ENSLBEP00000002486	Uncharacterized protein. (171 aa)
	ENSLBEP00000002967	Uncharacterized protein. (235 aa)
	ENSLBEP00000003253	annotation not available (109 aa)
	ep300	E1A binding protein p300 a. (2577 aa)
	ENSLBEP00000003961	annotation not available (130 aa)
	prmt3	Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (533 aa)
	ENSLBEP00000004878	Uncharacterized protein. (130 aa)
	LOC109982551	ATCAY kinesin light chain interacting caytaxin a. (372 aa)
	slc27a4	Solute carrier family 27 member 4. (643 aa)
	LOC110000969	PDZ domain containing 3b. (440 aa)
	brca1	Uncharacterized protein. (1180 aa)
	ENSLBEP00000007373	annotation not available (109 aa)
	ENSLBEP00000007480	annotation not available (109 aa)
	ENSLBEP00000007571	Uncharacterized protein. (120 aa)
	ENSLBEP00000007777	Uncharacterized protein. (237 aa)
	ENSLBEP00000017188	Uncharacterized protein. (231 aa)
	sirt1	Sirtuin 1. (681 aa)
	ENSLBEP00000017097	Uncharacterized protein. (248 aa)
	ENSLBEP00000016122	annotation not available (109 aa)
	ENSLBEP00000016080	Uncharacterized protein. (246 aa)
	ENSLBEP00000015863	Uncharacterized protein. (246 aa)
	ENSLBEP00000015082	Uncharacterized protein. (227 aa)
	ENSLBEP00000015001	annotation not available (109 aa)
	ENSLBEP00000014881	annotation not available (109 aa)
	ENSLBEP00000013855	annotation not available (109 aa)
	tigar	TP53 induced glycolysis regulatory phosphatase b. (270 aa)
	ENSLBEP00000013249	Zgc:158343. (156 aa)
	ENSLBEP00000013165	annotation not available (130 aa)
	ENSLBEP00000013078	Uncharacterized protein. (130 aa)
	ENSLBEP00000012281	annotation not available (252 aa)
	ENSLBEP00000012140	Uncharacterized protein. (246 aa)
	ENSLBEP00000011714	annotation not available (109 aa)
	ENSLBEP00000011452	Uncharacterized protein. (403 aa)
	ENSLBEP00000010929	Uncharacterized protein. (246 aa)
	ENSLBEP00000010178	Uncharacterized protein. (224 aa)
	ENSLBEP00000009394	annotation not available (109 aa)
	ENSLBEP00000009372	Uncharacterized protein. (226 aa)
	wdtc1	WD and tetratricopeptide repeats 1. (676 aa)
	ENSLBEP00000008517	Uncharacterized protein. (121 aa)
	ENSLBEP00000008271	annotation not available (109 aa)
	ENSLBEP00000008048	Uncharacterized protein. (118 aa)
	lepr	Leptin receptor. (1144 aa)
	ENSLBEP00000038700	Uncharacterized protein. (130 aa)
	ENSLBEP00000038769	Uncharacterized protein. (96 aa)
	ENSLBEP00000038780	annotation not available (109 aa)
	ENSLBEP00000038817	annotation not available (109 aa)
	ENSLBEP00000038847	annotation not available (109 aa)
	ENSLBEP00000038683	annotation not available (130 aa)
	ENSLBEP00000038588	Dickkopf WNT signaling pathway inhibitor 3b. (271 aa)
	ENSLBEP00000038435	annotation not available (109 aa)
	ENSLBEP00000038311	Uncharacterized protein. (124 aa)
	LOC109980752	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (142 aa)
	dkk3	Dickkopf WNT signaling pathway inhibitor 3a. (290 aa)
	LOC110004120	E1A binding protein p300 b. (2680 aa)
	pid1	Phosphotyrosine interaction domain containing 1. (229 aa)
	LOC109996796	TP53 induced glycolysis regulatory phosphatase a. (313 aa)
	ENSLBEP00000034550	annotation not available (252 aa)
	acmsd	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (337 aa)
	LOC109981720	Tribbles pseudokinase 3. (353 aa)
	ENSLBEP00000030325	Uncharacterized protein. (250 aa)
	ENSLBEP00000028697	annotation not available (227 aa)
	pibf1	Progesterone immunomodulatory binding factor 1. (765 aa)
	rd3	Retinal degeneration 3, GUCY2D regulator. (215 aa)
	ENSLBEP00000028223	annotation not available (109 aa)
	fam3c	Family with sequence similarity 3 member C. (437 aa)
	fgf19	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
	sirt4	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (329 aa)
	tspo	Translocator protein. (161 aa)
	ENSLBEP00000026358	Uncharacterized protein. (237 aa)
	SOGA1	Suppressor of glucose, autophagy associated 1. (1897 aa)
	ENSLBEP00000025001	Calponin-homology (CH) domain-containing protein. (272 aa)
	ENSLBEP00000024330	annotation not available (246 aa)
	LOC109975219	Uncharacterized protein. (251 aa)
	ENSLBEP00000023261	annotation not available (109 aa)
	ENSLBEP00000023183	annotation not available (246 aa)
	ENSLBEP00000023131	Uncharacterized protein. (207 aa)
	ENSLBEP00000022957	Uncharacterized protein. (212 aa)
	ENSLBEP00000022896	Uncharacterized protein. (128 aa)
	ENSLBEP00000022391	annotation not available (248 aa)
	ENSLBEP00000022272	TAZ-type domain-containing protein. (362 aa)
	flcn	Folliculin. (559 aa)
	ENSLBEP00000021554	Nuclear protein 1a. (67 aa)
	ENSLBEP00000021384	annotation not available (252 aa)
	ENSLBEP00000021288	annotation not available (109 aa)
	ENSLBEP00000021031	annotation not available (109 aa)
	ENSLBEP00000020859	Uncharacterized protein. (109 aa)
	ENSLBEP00000020840	Uncharacterized protein. (239 aa)
	ENSLBEP00000020286	annotation not available (109 aa)
	ENSLBEP00000020283	annotation not available (130 aa)
	ENSLBEP00000019881	Uncharacterized protein. (159 aa)
	ENSLBEP00000019858	annotation not available (109 aa)
	ENSLBEP00000019254	annotation not available (109 aa)
	ENSLBEP00000019028	Uncharacterized protein. (234 aa)
	ENSLBEP00000018592	Uncharacterized protein. (130 aa)
	ENSLBEP00000018383	annotation not available (252 aa)
	ENSLBEP00000018089	annotation not available (246 aa)
	ENSLBEP00000017509	Uncharacterized protein. (455 aa)
	ENSLBEP00000017435	annotation not available (246 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
	LOC109984270	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (169 aa)
	ENSLBEP00000017224	annotation not available (130 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000003961	ENSLBEP00000019881	ENSLBEP00000003961	ENSLBEP00000019881	annotation not available	Uncharacterized protein.	0.463
ENSLBEP00000004878	ENSLBEP00000019881	ENSLBEP00000004878	ENSLBEP00000019881	Uncharacterized protein.	Uncharacterized protein.	0.451
ENSLBEP00000013078	ENSLBEP00000019881	ENSLBEP00000013078	ENSLBEP00000019881	Uncharacterized protein.	Uncharacterized protein.	0.463
ENSLBEP00000013165	ENSLBEP00000019881	ENSLBEP00000013165	ENSLBEP00000019881	annotation not available	Uncharacterized protein.	0.463
ENSLBEP00000017224	ENSLBEP00000019881	ENSLBEP00000017224	ENSLBEP00000019881	annotation not available	Uncharacterized protein.	0.463
ENSLBEP00000019881	ENSLBEP00000003961	ENSLBEP00000019881	ENSLBEP00000003961	Uncharacterized protein.	annotation not available	0.463
ENSLBEP00000019881	ENSLBEP00000004878	ENSLBEP00000019881	ENSLBEP00000004878	Uncharacterized protein.	Uncharacterized protein.	0.451
ENSLBEP00000019881	ENSLBEP00000013078	ENSLBEP00000019881	ENSLBEP00000013078	Uncharacterized protein.	Uncharacterized protein.	0.463
ENSLBEP00000019881	ENSLBEP00000013165	ENSLBEP00000019881	ENSLBEP00000013165	Uncharacterized protein.	annotation not available	0.463
ENSLBEP00000019881	ENSLBEP00000017224	ENSLBEP00000019881	ENSLBEP00000017224	Uncharacterized protein.	annotation not available	0.463
ENSLBEP00000019881	ENSLBEP00000020283	ENSLBEP00000019881	ENSLBEP00000020283	Uncharacterized protein.	annotation not available	0.463
ENSLBEP00000019881	ENSLBEP00000022896	ENSLBEP00000019881	ENSLBEP00000022896	Uncharacterized protein.	Uncharacterized protein.	0.421
ENSLBEP00000019881	ENSLBEP00000038683	ENSLBEP00000019881	ENSLBEP00000038683	Uncharacterized protein.	annotation not available	0.463
ENSLBEP00000019881	ENSLBEP00000038700	ENSLBEP00000019881	ENSLBEP00000038700	Uncharacterized protein.	Uncharacterized protein.	0.446
ENSLBEP00000020283	ENSLBEP00000019881	ENSLBEP00000020283	ENSLBEP00000019881	annotation not available	Uncharacterized protein.	0.463
ENSLBEP00000022272	brca1	ENSLBEP00000022272	ENSLBEP00000007044	TAZ-type domain-containing protein.	Uncharacterized protein.	0.805
ENSLBEP00000022272	parp1	ENSLBEP00000022272	ENSLBEP00000017409	TAZ-type domain-containing protein.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.679
ENSLBEP00000022272	prmt3	ENSLBEP00000022272	ENSLBEP00000004835	TAZ-type domain-containing protein.	Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.579
ENSLBEP00000022272	sirt1	ENSLBEP00000022272	ENSLBEP00000017123	TAZ-type domain-containing protein.	Sirtuin 1.	0.740
ENSLBEP00000022272	sirt6	ENSLBEP00000022272	ENSLBEP00000001638	TAZ-type domain-containing protein.	Sirtuin 6.	0.418