(45 nodes) Regulation of biomineral tissue development network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLBEP00000007145	Uncharacterized protein. (233 aa)
	zmpste24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
	ENSLBEP00000007536	Phosphatase, orphan 1. (276 aa)
	ENSLBEP00000007637	Uncharacterized protein. (450 aa)
	LOC109982018	Refilin A. (220 aa)
	LOC110002853	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (574 aa)
	LOC109991813	NBR1 autophagy cargo receptor b. (1048 aa)
	LOC109995250	Alpha-2-HS-glycoprotein 2. (423 aa)
	bmpr2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1041 aa)
	ENSLBEP00000014278	Uncharacterized protein. (179 aa)
	LOC109992392	NBR1 autophagy cargo receptor a. (956 aa)
	gas6	Growth arrest-specific 6. (627 aa)
	ccn1	Cellular communication network factor 1. (374 aa)
	LOC109977902	Uncharacterized protein. (115 aa)
	LOC109981505	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
	LOC109986397	CCAAT enhancer binding protein beta. (294 aa)
	ENSLBEP00000022073	Uncharacterized protein. (225 aa)
	LOC109995483	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	LOC109981135	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (534 aa)
	LOC109983926	GATA binding protein 1a. (421 aa)
	rflnb	Refilin B. (210 aa)
	LOC110003880	BMP2 inducible kinase. (1158 aa)
	LOC109989158	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
	LOC109985782	Bone morphogenetic protein 16. (520 aa)
	acvr2b	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (480 aa)
	pth	Uncharacterized protein. (99 aa)
	ano6	Anoctamin. (920 aa)
	bmp4	Bone morphogenetic protein 4. (403 aa)
	LOC109985864	FAM20C golgi associated secretory pathway kinase a. (571 aa)
	GREM1	Gremlin. (182 aa)
	LOC109981718	Parathyroid hormone 4-like. (115 aa)
	ENSLBEP00000034439	Extracellular matrix protein 1a. (115 aa)
	LOC109985163	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (992 aa)
	LOC109990439	Fam20C domain-containing protein. (566 aa)
	wnt6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
	LOC109993821	Uncharacterized protein. (318 aa)
	pkdcc	Protein kinase domain containing, cytoplasmic b. (480 aa)
	phospho2	Phosphatase, orphan 2. (241 aa)
	tgfb3	Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
	bmpr1a	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
	LOC109989354	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (534 aa)
	LOC109987676	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	atraid	All-trans retinoic acid-induced differentiation factor. (231 aa)
	acvr2a	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
	LOC110005670	Protein kinase domain-containing protein. (977 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000007145	ENSLBEP00000007536	ENSLBEP00000007145	ENSLBEP00000007536	Uncharacterized protein.	Phosphatase, orphan 1.	0.842
ENSLBEP00000007536	ENSLBEP00000007145	ENSLBEP00000007536	ENSLBEP00000007145	Phosphatase, orphan 1.	Uncharacterized protein.	0.842
ENSLBEP00000014278	LOC109981135	ENSLBEP00000014278	ENSLBEP00000023544	Uncharacterized protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.422
ENSLBEP00000014278	LOC109981505	ENSLBEP00000014278	ENSLBEP00000019586	Uncharacterized protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.447
ENSLBEP00000014278	LOC109983926	ENSLBEP00000014278	ENSLBEP00000023574	Uncharacterized protein.	GATA binding protein 1a.	0.523
ENSLBEP00000014278	LOC109985163	ENSLBEP00000014278	ENSLBEP00000033377	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.447
ENSLBEP00000014278	LOC109989158	ENSLBEP00000014278	ENSLBEP00000026842	Uncharacterized protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.422
ENSLBEP00000014278	LOC109989354	ENSLBEP00000014278	ENSLBEP00000001646	Uncharacterized protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.447
ENSLBEP00000014278	LOC109991813	ENSLBEP00000014278	ENSLBEP00000010116	Uncharacterized protein.	NBR1 autophagy cargo receptor b.	0.982
ENSLBEP00000014278	LOC109992392	ENSLBEP00000014278	ENSLBEP00000014151	Uncharacterized protein.	NBR1 autophagy cargo receptor a.	0.998
ENSLBEP00000014278	acvr2a	ENSLBEP00000014278	ENSLBEP00000006162	Uncharacterized protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.447
ENSLBEP00000014278	acvr2b	ENSLBEP00000014278	ENSLBEP00000027268	Uncharacterized protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.447
ENSLBEP00000014278	bmpr1a	ENSLBEP00000014278	ENSLBEP00000000624	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.422
ENSLBEP00000014278	bmpr2	ENSLBEP00000014278	ENSLBEP00000012194	Uncharacterized protein.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.447
ENSLBEP00000014278	pkdcc	ENSLBEP00000014278	ENSLBEP00000028513	Uncharacterized protein.	Protein kinase domain containing, cytoplasmic b.	0.499
GREM1	LOC109985782	ENSLBEP00000035477	ENSLBEP00000026844	Gremlin.	Bone morphogenetic protein 16.	0.870
GREM1	LOC109987676	ENSLBEP00000035477	ENSLBEP00000001759	Gremlin.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.481
GREM1	LOC109995483	ENSLBEP00000035477	ENSLBEP00000022560	Gremlin.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.507
GREM1	bmp4	ENSLBEP00000035477	ENSLBEP00000038352	Gremlin.	Bone morphogenetic protein 4.	0.870
GREM1	tgfb3	ENSLBEP00000035477	ENSLBEP00000000548	Gremlin.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.481