(22 nodes) Necrotic cell death network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109989921	Uncharacterized protein. (475 aa)
	LOC109981905	Uncharacterized protein. (315 aa)
	MLKL	Mixed lineage kinase domain like pseudokinase. (446 aa)
	ENSLBEP00000007935	Ninjurin 1. (130 aa)
	LOC109982580	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (266 aa)
	ipmk	Kinase; Belongs to the inositol phosphokinase (IPK) family. (586 aa)
	ENSLBEP00000014784	Uncharacterized protein. (172 aa)
	LOC109991906	Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family. (384 aa)
	LOC109998157	Uncharacterized protein; Belongs to the protein kinase superfamily. (449 aa)
	LOC109975131	Uncharacterized protein. (303 aa)
	LOC109992051	Tumor necrosis factor b (TNF superfamily, member 2). (253 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (683 aa)
	LOC109983871-2	Cylindromatosis (turban tumor syndrome), b. (705 aa)
	alkbh7	AlkB homolog 7. (231 aa)
	itpk1	Inositol-tetrakisphosphate 1-kinase b. (430 aa)
	fadd	Uncharacterized protein. (192 aa)
	LOC109995595	Uncharacterized protein. (994 aa)
	LOC109995578	Receptor-interacting serine-threonine kinase 3. (494 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (956 aa)
	bax	BCL2 associated X, apoptosis regulator a. (192 aa)
	LOC109989015	Interferon regulatory factor 3. (465 aa)
	GSDME	Gasdermin E. (531 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109975131	LOC109982580	ENSLBEP00000020348	ENSLBEP00000010375	Uncharacterized protein.	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	0.987
LOC109975131	LOC109995578	ENSLBEP00000020348	ENSLBEP00000029624	Uncharacterized protein.	Receptor-interacting serine-threonine kinase 3.	0.646
LOC109975131	LOC109998157	ENSLBEP00000020348	ENSLBEP00000016647	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.646
LOC109975131	MLKL	ENSLBEP00000020348	ENSLBEP00000006884	Uncharacterized protein.	Mixed lineage kinase domain like pseudokinase.	0.417
LOC109975131	fadd	ENSLBEP00000020348	ENSLBEP00000028812	Uncharacterized protein.	Uncharacterized protein.	0.993
LOC109975131	ripk1	ENSLBEP00000020348	ENSLBEP00000022169	Uncharacterized protein.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.849
LOC109981905	LOC109982580	ENSLBEP00000004867	ENSLBEP00000010375	Uncharacterized protein.	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	0.987
LOC109981905	LOC109995578	ENSLBEP00000004867	ENSLBEP00000029624	Uncharacterized protein.	Receptor-interacting serine-threonine kinase 3.	0.646
LOC109981905	LOC109998157	ENSLBEP00000004867	ENSLBEP00000016647	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.646
LOC109981905	MLKL	ENSLBEP00000004867	ENSLBEP00000006884	Uncharacterized protein.	Mixed lineage kinase domain like pseudokinase.	0.417
LOC109981905	fadd	ENSLBEP00000004867	ENSLBEP00000028812	Uncharacterized protein.	Uncharacterized protein.	0.993
LOC109981905	ripk1	ENSLBEP00000004867	ENSLBEP00000022169	Uncharacterized protein.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.849
LOC109982580	LOC109975131	ENSLBEP00000010375	ENSLBEP00000020348	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.987
LOC109982580	LOC109981905	ENSLBEP00000010375	ENSLBEP00000004867	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.987
LOC109982580	LOC109995578	ENSLBEP00000010375	ENSLBEP00000029624	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Receptor-interacting serine-threonine kinase 3.	0.586
LOC109982580	LOC109998157	ENSLBEP00000010375	ENSLBEP00000016647	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.586
LOC109982580	fadd	ENSLBEP00000010375	ENSLBEP00000028812	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Uncharacterized protein.	0.979
LOC109982580	ripk1	ENSLBEP00000010375	ENSLBEP00000022169	Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.791
LOC109983871-2	LOC109995578	ENSLBEP00000023025	ENSLBEP00000029624	Cylindromatosis (turban tumor syndrome), b.	Receptor-interacting serine-threonine kinase 3.	0.682
LOC109983871-2	LOC109995595	ENSLBEP00000023025	ENSLBEP00000029408	Cylindromatosis (turban tumor syndrome), b.	Uncharacterized protein.	0.851