(13 nodes) ER-associated misfolded protein catabolic process network (Labrus bergylta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	derl1	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (250 aa)
	RNF5	Ring finger protein 5. (156 aa)
	ENSLBEP00000013502	Ubiquitin-like domain-containing protein. (149 aa)
	bag6	BCL2 associated athanogene 6, like. (1138 aa)
	rnf5	RING-type domain-containing protein. (216 aa)
	aup1	AUP1 lipid droplet regulating VLDL assembly factor. (415 aa)
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	LOC109992030	BCL2 associated athanogene 6. (1142 aa)
	LOC110000677	Zgc:136908; Belongs to the AAA ATPase family. (802 aa)
	uggt1	UDP-glucose glycoprotein glucosyltransferase 1. (1613 aa)
	uggt2	UDP-glucose glycoprotein glucosyltransferase 2. (1557 aa)
	rnf185	zf-C3HC4 domain-containing protein. (219 aa)
	ufd1	Ubiquitin recognition factor in ER associated degradation 1. (276 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000013502	LOC110000677	ENSLBEP00000013502	ENSLBEP00000023113	Ubiquitin-like domain-containing protein.	Zgc:136908; Belongs to the AAA ATPase family.	0.409
ENSLBEP00000013502	vcp	ENSLBEP00000013502	ENSLBEP00000019661	Ubiquitin-like domain-containing protein.	Valosin containing protein; Belongs to the AAA ATPase family.	0.409
LOC109992030	LOC110000677	ENSLBEP00000021896	ENSLBEP00000023113	BCL2 associated athanogene 6.	Zgc:136908; Belongs to the AAA ATPase family.	0.409
LOC109992030	vcp	ENSLBEP00000021896	ENSLBEP00000019661	BCL2 associated athanogene 6.	Valosin containing protein; Belongs to the AAA ATPase family.	0.409
LOC110000677	ENSLBEP00000013502	ENSLBEP00000023113	ENSLBEP00000013502	Zgc:136908; Belongs to the AAA ATPase family.	Ubiquitin-like domain-containing protein.	0.409
LOC110000677	LOC109992030	ENSLBEP00000023113	ENSLBEP00000021896	Zgc:136908; Belongs to the AAA ATPase family.	BCL2 associated athanogene 6.	0.409
LOC110000677	RNF5	ENSLBEP00000023113	ENSLBEP00000010133	Zgc:136908; Belongs to the AAA ATPase family.	Ring finger protein 5.	0.654
LOC110000677	aup1	ENSLBEP00000023113	ENSLBEP00000018226	Zgc:136908; Belongs to the AAA ATPase family.	AUP1 lipid droplet regulating VLDL assembly factor.	0.604
LOC110000677	bag6	ENSLBEP00000023113	ENSLBEP00000016524	Zgc:136908; Belongs to the AAA ATPase family.	BCL2 associated athanogene 6, like.	0.409
LOC110000677	derl1	ENSLBEP00000023113	ENSLBEP00000007466	Zgc:136908; Belongs to the AAA ATPase family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.981
LOC110000677	rnf185	ENSLBEP00000023113	ENSLBEP00000026019	Zgc:136908; Belongs to the AAA ATPase family.	zf-C3HC4 domain-containing protein.	0.654
LOC110000677	rnf5	ENSLBEP00000023113	ENSLBEP00000016659	Zgc:136908; Belongs to the AAA ATPase family.	RING-type domain-containing protein.	0.654
LOC110000677	ufd1	ENSLBEP00000023113	ENSLBEP00000033551	Zgc:136908; Belongs to the AAA ATPase family.	Ubiquitin recognition factor in ER associated degradation 1.	0.986
RNF5	LOC110000677	ENSLBEP00000010133	ENSLBEP00000023113	Ring finger protein 5.	Zgc:136908; Belongs to the AAA ATPase family.	0.654
RNF5	derl1	ENSLBEP00000010133	ENSLBEP00000007466	Ring finger protein 5.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.831
RNF5	vcp	ENSLBEP00000010133	ENSLBEP00000019661	Ring finger protein 5.	Valosin containing protein; Belongs to the AAA ATPase family.	0.654
aup1	LOC110000677	ENSLBEP00000018226	ENSLBEP00000023113	AUP1 lipid droplet regulating VLDL assembly factor.	Zgc:136908; Belongs to the AAA ATPase family.	0.604
aup1	vcp	ENSLBEP00000018226	ENSLBEP00000019661	AUP1 lipid droplet regulating VLDL assembly factor.	Valosin containing protein; Belongs to the AAA ATPase family.	0.604
bag6	LOC110000677	ENSLBEP00000016524	ENSLBEP00000023113	BCL2 associated athanogene 6, like.	Zgc:136908; Belongs to the AAA ATPase family.	0.409
bag6	vcp	ENSLBEP00000016524	ENSLBEP00000019661	BCL2 associated athanogene 6, like.	Valosin containing protein; Belongs to the AAA ATPase family.	0.409