(27 nodes) Stem cell proliferation network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ism1	Isthmin 1. (458 aa)
	ENSLBEP00000037371	FZ domain-containing protein. (284 aa)
	ETV6	ETS variant 6. (518 aa)
	LOC109996736	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)
	trim71	Tripartite motif containing 71, E3 ubiquitin protein ligase. (810 aa)
	LOC109985155	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
	mettl3	Methyltransferase like 3; Belongs to the MT-A70-like family. (592 aa)
	LOC109982371	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (229 aa)
	nf1	Neurofibromin 1b. (2672 aa)
	LOC109995483	Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
	LOC109982800	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (178 aa)
	lig4	DNA ligase. (827 aa)
	bysl	Uncharacterized protein. (439 aa)
	LOC109979124	Helicase ATP-binding domain-containing protein. (628 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	znrf3	Zinc and ring finger 3. (891 aa)
	arih2	RBR-type E3 ubiquitin transferase. (508 aa)
	kdf1	Keratinocyte differentiation factor 1a. (404 aa)
	cep120	Centrosomal protein 120. (934 aa)
	rnf43	RING-type domain-containing protein. (725 aa)
	mecom	MDS1 and EVI1 complex locus. (1262 aa)
	LOC109990537	YTH N(6)-methyladenosine RNA binding protein 2. (646 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	xrcc5	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (724 aa)
	LOC109984746	Tower domain-containing protein. (922 aa)
	ENSLBEP00000002749	Uncharacterized protein. (926 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000002749	LOC109979124	ENSLBEP00000002749	ENSLBEP00000014717	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.764
ENSLBEP00000002749	LOC109984746	ENSLBEP00000002749	ENSLBEP00000002832	Uncharacterized protein.	Tower domain-containing protein.	0.897
ENSLBEP00000002749	ercc2	ENSLBEP00000002749	ENSLBEP00000013761	Uncharacterized protein.	Excision repair cross-complementation group 2.	0.764
ENSLBEP00000002749	lig4	ENSLBEP00000002749	ENSLBEP00000018958	Uncharacterized protein.	DNA ligase.	0.518
ENSLBEP00000002749	nf1	ENSLBEP00000002749	ENSLBEP00000026060	Uncharacterized protein.	Neurofibromin 1b.	0.429
ENSLBEP00000002749	xrcc5	ENSLBEP00000002749	ENSLBEP00000004321	Uncharacterized protein.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.483
ENSLBEP00000037371	rnf43	ENSLBEP00000037371	ENSLBEP00000007791	FZ domain-containing protein.	RING-type domain-containing protein.	0.630
ENSLBEP00000037371	znrf3	ENSLBEP00000037371	ENSLBEP00000010658	FZ domain-containing protein.	Zinc and ring finger 3.	0.580
LOC109979124	ENSLBEP00000002749	ENSLBEP00000014717	ENSLBEP00000002749	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.764
LOC109979124	LOC109984746	ENSLBEP00000014717	ENSLBEP00000002832	Helicase ATP-binding domain-containing protein.	Tower domain-containing protein.	0.764
LOC109979124	lig4	ENSLBEP00000014717	ENSLBEP00000018958	Helicase ATP-binding domain-containing protein.	DNA ligase.	0.666
LOC109979124	xrcc5	ENSLBEP00000014717	ENSLBEP00000004321	Helicase ATP-binding domain-containing protein.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.440
LOC109982371	fgf2	ENSLBEP00000026874	ENSLBEP00000001977	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.432
LOC109984746	ENSLBEP00000002749	ENSLBEP00000002832	ENSLBEP00000002749	Tower domain-containing protein.	Uncharacterized protein.	0.897
LOC109984746	LOC109979124	ENSLBEP00000002832	ENSLBEP00000014717	Tower domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.764
LOC109984746	ercc2	ENSLBEP00000002832	ENSLBEP00000013761	Tower domain-containing protein.	Excision repair cross-complementation group 2.	0.764
LOC109984746	lig4	ENSLBEP00000002832	ENSLBEP00000018958	Tower domain-containing protein.	DNA ligase.	0.518
LOC109984746	nf1	ENSLBEP00000002832	ENSLBEP00000026060	Tower domain-containing protein.	Neurofibromin 1b.	0.429
LOC109984746	xrcc5	ENSLBEP00000002832	ENSLBEP00000004321	Tower domain-containing protein.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.483
LOC109985155	fgf2	ENSLBEP00000028869	ENSLBEP00000001977	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.416