(26 nodes) Energy homeostasis network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109987528	Nuclear receptor subfamily 1, group D, member 2b. (586 aa)
	LOC109987072	Endothelin 2. (219 aa)
	CRTC1	CREB regulated transcription coactivator 1b. (603 aa)
	LOC109988834	Nuclear receptor subfamily 1, group D, member 2a. (658 aa)
	lepr	Leptin receptor. (1144 aa)
	ENSLBEP00000008522	Melanocortin 4 receptor. (318 aa)
	oma1	OMA1 zinc metallopeptidase. (510 aa)
	prkaa2	Non-specific serine/threonine protein kinase. (557 aa)
	LOC109984954	Nuclear receptor subfamily 1, group D, member 4a. (575 aa)
	irx3	Iroquois homeobox 3a. (428 aa)
	sirt1	Sirtuin 1. (681 aa)
	ENSLBEP00000018282	CREB regulated transcription coactivator 1a. (380 aa)
	flcn	Folliculin. (559 aa)
	SLC35D3	Solute carrier family 35 member D3. (367 aa)
	LOC109992496	Nuclear receptor subfamily 1, group D, member 4b. (572 aa)
	tsku	Tsukushi small leucine rich proteoglycan homolog (Xenopus laevis). (348 aa)
	mrap2	Melanocortin 2 receptor accessory protein 2b. (229 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (989 aa)
	pm20d1	Peptidase M20 domain containing 1, tandem duplicate 2. (522 aa)
	rrp8	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (384 aa)
	nmu	NMU domain-containing protein. (139 aa)
	metrnl	Meteorin like, glial cell differentiation regulator a. (286 aa)
	ENSLBEP00000030841	Protein kinase domain-containing protein. (574 aa)
	sqstm1	Sequestosome 1. (272 aa)
	ENSLBEP00000032673	PB1 domain-containing protein. (108 aa)
	prkaa1	Non-specific serine/threonine protein kinase. (573 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRTC1	ppargc1a	ENSLBEP00000002928	ENSLBEP00000025662	CREB regulated transcription coactivator 1b.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.532
ENSLBEP00000008522	lepr	ENSLBEP00000008522	ENSLBEP00000007993	Melanocortin 4 receptor.	Leptin receptor.	0.559
ENSLBEP00000008522	mrap2	ENSLBEP00000008522	ENSLBEP00000025574	Melanocortin 4 receptor.	Melanocortin 2 receptor accessory protein 2b.	0.639
ENSLBEP00000008522	nmu	ENSLBEP00000008522	ENSLBEP00000026773	Melanocortin 4 receptor.	NMU domain-containing protein.	0.466
ENSLBEP00000018282	ppargc1a	ENSLBEP00000018282	ENSLBEP00000025662	CREB regulated transcription coactivator 1a.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.532
ENSLBEP00000030841	lepr	ENSLBEP00000030841	ENSLBEP00000007993	Protein kinase domain-containing protein.	Leptin receptor.	0.456
ENSLBEP00000032673	sqstm1	ENSLBEP00000032673	ENSLBEP00000032661	PB1 domain-containing protein.	Sequestosome 1.	0.444
LOC109984954	ppargc1a	ENSLBEP00000013615	ENSLBEP00000025662	Nuclear receptor subfamily 1, group D, member 4a.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.599
LOC109984954	sirt1	ENSLBEP00000013615	ENSLBEP00000017123	Nuclear receptor subfamily 1, group D, member 4a.	Sirtuin 1.	0.489
LOC109987528	ppargc1a	ENSLBEP00000036659	ENSLBEP00000025662	Nuclear receptor subfamily 1, group D, member 2b.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.599
LOC109987528	sirt1	ENSLBEP00000036659	ENSLBEP00000017123	Nuclear receptor subfamily 1, group D, member 2b.	Sirtuin 1.	0.489
LOC109988834	ppargc1a	ENSLBEP00000004168	ENSLBEP00000025662	Nuclear receptor subfamily 1, group D, member 2a.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.599
LOC109988834	sirt1	ENSLBEP00000004168	ENSLBEP00000017123	Nuclear receptor subfamily 1, group D, member 2a.	Sirtuin 1.	0.489
LOC109992496	ppargc1a	ENSLBEP00000022999	ENSLBEP00000025662	Nuclear receptor subfamily 1, group D, member 4b.	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.	0.599
LOC109992496	sirt1	ENSLBEP00000022999	ENSLBEP00000017123	Nuclear receptor subfamily 1, group D, member 4b.	Sirtuin 1.	0.480
flcn	prkaa1	ENSLBEP00000022070	ENSLBEP00000033114	Folliculin.	Non-specific serine/threonine protein kinase.	0.433
flcn	prkaa2	ENSLBEP00000022070	ENSLBEP00000012772	Folliculin.	Non-specific serine/threonine protein kinase.	0.433
lepr	ENSLBEP00000008522	ENSLBEP00000007993	ENSLBEP00000008522	Leptin receptor.	Melanocortin 4 receptor.	0.559
lepr	ENSLBEP00000030841	ENSLBEP00000007993	ENSLBEP00000030841	Leptin receptor.	Protein kinase domain-containing protein.	0.456
metrnl	sirt1	ENSLBEP00000027539	ENSLBEP00000017123	Meteorin like, glial cell differentiation regulator a.	Sirtuin 1.	0.593