(127 nodes) Synaptic vesicle cycle network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLBEP00000030805	DENN/MADD domain containing 1A. (421 aa)
	LOC109996076	SH3-domain GRB2-like 1b. (351 aa)
	LOC109981137	G protein-coupled receptor kinase interacting ArfGAP 2b. (663 aa)
	ENSLBEP00000022834	COesterase domain-containing protein. (255 aa)
	cplx4	Complexin 4a. (159 aa)
	LOC109997741	Neuroligin 4 X-linked a. (874 aa)
	RIMS1	Regulating synaptic membrane exocytosis 1. (1422 aa)
	slc17a6	Solute carrier family 17 member 6. (581 aa)
	LOC109989139	Uncharacterized protein. (1460 aa)
	LOC109986742	MFS domain-containing protein. (585 aa)
	LOC109989118	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (818 aa)
	ENSLBEP00000021028	SynN domain-containing protein. (193 aa)
	sh3gl2	SH3 domain containing GRB2 like 2a, endophilin A1. (368 aa)
	synj1	Synaptojanin 1. (1449 aa)
	LOC109998029	ELKS/RAB6-interacting/CAST family member 1. (1188 aa)
	ENSLBEP00000019755	Uncharacterized protein. (274 aa)
	ENSLBEP00000019157	Uncharacterized protein. (83 aa)
	LOC109998683	Piccolo presynaptic cytomatrix protein a. (2621 aa)
	LOC109983245	Otoferlin a. (2032 aa)
	LOC109998728	Neuroligin 1. (622 aa)
	ENSLBEP00000016589	Uncharacterized protein. (184 aa)
	LOC109986243	Solute carrier family 32 member 1. (526 aa)
	ENSLBEP00000016420	Aa_trans domain-containing protein. (547 aa)
	LOC109989547	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (837 aa)
	ENSLBEP00000015692	Synaptotagmin Ib. (365 aa)
	LOC109982784	Uncharacterized protein. (1584 aa)
	cplx3	Complexin 3b. (156 aa)
	dnm1	Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (851 aa)
	erc2	ELKS/RAB6-interacting/CAST family member 2. (1152 aa)
	LOC109990773	Uncharacterized protein; Belongs to the synuclein family. (123 aa)
	LOC110003064	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (257 aa)
	STX11	Syntaxin 11; Belongs to the syntaxin family. (300 aa)
	git1	G protein-coupled receptor kinase interacting ArfGAP 1. (787 aa)
	LOC109996130	Uncharacterized protein. (1147 aa)
	ENSLBEP00000025650	Uncharacterized protein. (203 aa)
	LOC109994898	Ca2+-dependent activator protein for secretion a. (1222 aa)
	AP3B2	AP-3 complex subunit beta. (988 aa)
	LOC110002613	Syntaxin 1B; Belongs to the syntaxin family. (302 aa)
	kiaa1109	Si:ch211-233a24.2. (4980 aa)
	syt12	Synaptotagmin XII. (429 aa)
	fcho2	FCH domain only 2. (1034 aa)
	fer1l6	Fer-1 like family member 6. (1740 aa)
	unc13b	Uncharacterized protein. (1546 aa)
	LOC109993212	Phosphatidylinositol binding clathrin assembly protein a. (623 aa)
	syt1	Synaptotagmin Ia. (417 aa)
	LOC109985770	Syntaxin 1A (brain); Belongs to the syntaxin family. (323 aa)
	PCLO	Piccolo presynaptic cytomatrix protein. (4666 aa)
	snap25	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (205 aa)
	LOC109995586	Si:ch211-200p22.4. (617 aa)
	ENSLBEP00000030320	Proline-rich transmembrane protein 2. (189 aa)
	LOC109987944	Intersectin 1 (SH3 domain protein). (1614 aa)
	LOC109983327	Synapsin I. (577 aa)
	SLC17A7	Solute carrier family 17 member 7. (636 aa)
	LOC109999181	Phosphatidylinositol binding clathrin assembly protein b. (736 aa)
	LOC109989222	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (878 aa)
	ENSLBEP00000031587	C2 domain-containing protein. (276 aa)
	SYT2	Synaptotagmin 2. (433 aa)
	snapin	SNAP associated protein. (152 aa)
	LOC109991545	Synaptosome associated protein 29. (260 aa)
	LOC109993917	Uncharacterized protein. (1240 aa)
	LOC109983340	Syntaxin 2b; Belongs to the syntaxin family. (293 aa)
	LOC109988704	Synaptotagmin Vb. (423 aa)
	syn2	Synapsin IIb. (821 aa)
	LOC110002760	Uncharacterized protein. (347 aa)
	LOC109985265	Neuroligin 3b. (820 aa)
	LOC109993317	Synuclein, gamma b (breast cancer-specific protein 1); Belongs to the synuclein family. (113 aa)
	ENSLBEP00000035741	MFS domain-containing protein. (450 aa)
	LOC109976661	Gamma-synuclein; Belongs to the synuclein family. (123 aa)
	ENSLBEP00000000603	Uncharacterized protein. (367 aa)
	LOC109983014	Synaptotagmin VIIb. (568 aa)
	LOC109984025	Unc-13 homolog A. (1562 aa)
	LOC109975404	C2 domain-containing protein. (309 aa)
	LOC109996820	ENTH domain-containing protein. (575 aa)
	LOC109984031	SH3-domain GRB2-like 1a. (368 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	LOC109991031	Neuroligin 2b. (659 aa)
	SLC17A6	Solute carrier family 17 member 6b. (581 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2422 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1648 aa)
	rims3	Regulating synaptic membrane exocytosis 3. (324 aa)
	LOC110001653	Synaptotagmin IXa. (563 aa)
	ENSLBEP00000003521	COesterase domain-containing protein. (228 aa)
	snap91	Synaptosome associated protein 91a. (946 aa)
	LOC110002303	Ca2+-dependent activator protein for secretion b. (748 aa)
	LOC109978860	Synaptosome associated protein 29. (250 aa)
	ENSLBEP00000004788	Uncharacterized protein. (63 aa)
	LOC109985352	COesterase domain-containing protein. (865 aa)
	cadps2	Ca++-dependent secretion activator 2. (1186 aa)
	nostrin	Nitric oxide synthase trafficking. (574 aa)
	LOC109977797	Syntaxin 11a; Belongs to the syntaxin family. (293 aa)
	LOC109978224	t-SNARE coiled-coil homology domain-containing protein. (294 aa)
	ENSLBEP00000007269	ENTH domain-containing protein. (56 aa)
	ap3d1	Adaptor related protein complex 3 subunit delta 1. (1261 aa)
	LOC110002836	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (204 aa)
	cplx2	Complexin 2. (134 aa)
	LOC109987127	Aa_trans domain-containing protein. (522 aa)
	git2	G protein-coupled receptor kinase interacting ArfGAP 2a. (760 aa)
	LOC109980995	Synapsin IIa. (467 aa)
	LOC110002853	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (574 aa)
	ENSLBEP00000009747	Synaptosome associated protein 91b. (593 aa)
	LOC110004443	COesterase domain-containing protein. (826 aa)
	LOC109985771	Synaptotagmin IIa. (433 aa)
	LOC109990056	Intersectin 2a. (1567 aa)
	ENSLBEP00000011262	Neuroligin 2a. (532 aa)
	erc1	ELKS/RAB6-interacting/CAST family member 1a. (1133 aa)
	dnm3	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (828 aa)
	snap23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (235 aa)
	snap47	Synaptosome associated protein 47. (407 aa)
	stx3	Syntaxin 3A; Belongs to the syntaxin family. (294 aa)
	LOC109995936	Syntaxin 4; Belongs to the syntaxin family. (297 aa)
	UNC13C	Unc-13 homolog C. (2098 aa)
	LOC110004917	Synaptotagmin VIIb. (345 aa)
	LOC110001663	SH3-domain GRB2-like 3a. (384 aa)
	nlgn3	Neuroligin 3a. (858 aa)
	ENSLBEP00000035904	Adaptin_N domain-containing protein. (179 aa)
	LOC109988105	Beta-synuclein; Belongs to the synuclein family. (118 aa)
	SYN3	Synapsin III. (534 aa)
	LOC110002040	Solute carrier family 17 member 8. (581 aa)
	LOC109981723	Si:ch73-389b16.2. (1558 aa)
	STX19	Syntaxin 19. (302 aa)
	slc18a2	Solute carrier family 18 member 2. (516 aa)
	SYNDIG1	Synapse differentiation inducing 1. (258 aa)
	LOC109992751	Synaptotagmin IXb. (495 aa)
	ENSLBEP00000038784	MFS domain-containing protein. (381 aa)
	ENSLBEP00000014949	Uncharacterized protein. (181 aa)
	CPLX1	Complexin 1. (133 aa)
	LOC109996390	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (833 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP3B2	ENSLBEP00000007269	ENSLBEP00000026537	ENSLBEP00000007269	AP-3 complex subunit beta.	ENTH domain-containing protein.	0.528
AP3B2	ENSLBEP00000009747	ENSLBEP00000026537	ENSLBEP00000009747	AP-3 complex subunit beta.	Synaptosome associated protein 91b.	0.528
AP3B2	ENSLBEP00000035904	ENSLBEP00000026537	ENSLBEP00000035904	AP-3 complex subunit beta.	Adaptin_N domain-containing protein.	0.840
AP3B2	LOC109984031	ENSLBEP00000026537	ENSLBEP00000001826	AP-3 complex subunit beta.	SH3-domain GRB2-like 1a.	0.537
AP3B2	LOC109989118	ENSLBEP00000026537	ENSLBEP00000021448	AP-3 complex subunit beta.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.519
AP3B2	LOC109989222	ENSLBEP00000026537	ENSLBEP00000031494	AP-3 complex subunit beta.	Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.519
AP3B2	LOC109989547	ENSLBEP00000026537	ENSLBEP00000016159	AP-3 complex subunit beta.	Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.519
AP3B2	LOC109993212	ENSLBEP00000026537	ENSLBEP00000028633	AP-3 complex subunit beta.	Phosphatidylinositol binding clathrin assembly protein a.	0.528
AP3B2	LOC109995586	ENSLBEP00000026537	ENSLBEP00000030106	AP-3 complex subunit beta.	Si:ch211-200p22.4.	0.528
AP3B2	LOC109996076	ENSLBEP00000026537	ENSLBEP00000022978	AP-3 complex subunit beta.	SH3-domain GRB2-like 1b.	0.544
AP3B2	LOC109996390	ENSLBEP00000026537	ENSLBEP00000015415	AP-3 complex subunit beta.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.519
AP3B2	LOC109996820	ENSLBEP00000026537	ENSLBEP00000001624	AP-3 complex subunit beta.	ENTH domain-containing protein.	0.528
AP3B2	LOC109999181	ENSLBEP00000026537	ENSLBEP00000031418	AP-3 complex subunit beta.	Phosphatidylinositol binding clathrin assembly protein b.	0.528
AP3B2	LOC110001663	ENSLBEP00000026537	ENSLBEP00000014079	AP-3 complex subunit beta.	SH3-domain GRB2-like 3a.	0.544
AP3B2	LOC110002760	ENSLBEP00000026537	ENSLBEP00000034065	AP-3 complex subunit beta.	Uncharacterized protein.	0.544
AP3B2	ap3d1	ENSLBEP00000026537	ENSLBEP00000007393	AP-3 complex subunit beta.	Adaptor related protein complex 3 subunit delta 1.	0.995
AP3B2	dnm1	ENSLBEP00000026537	ENSLBEP00000023902	AP-3 complex subunit beta.	Dynamin 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.519
AP3B2	dnm3	ENSLBEP00000026537	ENSLBEP00000011877	AP-3 complex subunit beta.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.519
AP3B2	sh3gl2	ENSLBEP00000026537	ENSLBEP00000020923	AP-3 complex subunit beta.	SH3 domain containing GRB2 like 2a, endophilin A1.	0.544
AP3B2	snap91	ENSLBEP00000026537	ENSLBEP00000004047	AP-3 complex subunit beta.	Synaptosome associated protein 91a.	0.528