STRINGSTRING
msh2 msh2 n6amt1 n6amt1 top2b top2b hells hells zranb3 zranb3 LOC109989370 LOC109989370 pms1 pms1 twnk twnk hltf hltf LOC110002098 LOC110002098 LOC109980699 LOC109980699 ENSLBEP00000038445 ENSLBEP00000038445 ENSLBEP00000038538 ENSLBEP00000038538 LOC109979646 LOC109979646 ENSLBEP00000038685 ENSLBEP00000038685 LOC109989976 LOC109989976 blm blm LOC109990300 LOC109990300 tdp2 tdp2 LOC109986347 LOC109986347 dkc1 dkc1 recql5 recql5 mcm8 mcm8 LOC110001857 LOC110001857 LOC109983927 LOC109983927 ENSLBEP00000025729 ENSLBEP00000025729 dffb dffb ddx11 ddx11 LOC109976496 LOC109976496 LOC110005319 LOC110005319 dnase1l3 dnase1l3 LOC109993082 LOC109993082 LOC109983279 LOC109983279 LOC109994357 LOC109994357 dnmt1 dnmt1 chd7 chd7 rps3 rps3 APTX APTX ENSLBEP00000028573 ENSLBEP00000028573 polk polk mettl4 mettl4 pgbd5 pgbd5 LOC110004773 LOC110004773 polm polm mcm3 mcm3 dclre1c dclre1c ankle1 ankle1 ENSLBEP00000030170 ENSLBEP00000030170 LOC109980655 LOC109980655 LOC109975320 LOC109975320 LOC109975370 LOC109975370 pold1 pold1 dhx36 dhx36 recql recql mcm5 mcm5 fbh1 fbh1 tert tert rad54l rad54l ENSLBEP00000019134 ENSLBEP00000019134 ENSLBEP00000019263 ENSLBEP00000019263 ttf2 ttf2 neil3 neil3 rtel1 rtel1 fan1 fan1 LOC109978422 LOC109978422 ENSLBEP00000020198 ENSLBEP00000020198 dclre1b dclre1b endog endog ENSLBEP00000020343 ENSLBEP00000020343 top2a top2a ENSLBEP00000020439 ENSLBEP00000020439 ENSLBEP00000020673 ENSLBEP00000020673 mus81 mus81 knl1 knl1 msh6 msh6 LOC110003012 LOC110003012 ENSLBEP00000021724 ENSLBEP00000021724 LOC109976362 LOC109976362 wrnip1 wrnip1 LOC110002533 LOC110002533 ENSLBEP00000022376 ENSLBEP00000022376 pola1 pola1 smug1 smug1 smarca4 smarca4 ENSLBEP00000023018 ENSLBEP00000023018 MUTYH MUTYH LOC109983919 LOC109983919 ENSLBEP00000023366 ENSLBEP00000023366 ruvbl1 ruvbl1 rad1 rad1 smarca5 smarca5 top3a top3a rev1 rev1 ENSLBEP00000024278 ENSLBEP00000024278 ENSLBEP00000019089 ENSLBEP00000019089 LOC109982170 LOC109982170 ercc6 ercc6 lig4 lig4 LOC109985460 LOC109985460 msh3 msh3 ENSLBEP00000018564 ENSLBEP00000018564 ENSLBEP00000018189 ENSLBEP00000018189 ENSLBEP00000018112 ENSLBEP00000018112 SMARCA1 SMARCA1 mlh1 mlh1 ENDOV ENDOV ENSLBEP00000016945 ENSLBEP00000016945 ENSLBEP00000016887 ENSLBEP00000016887 mpg mpg ENSLBEP00000016728 ENSLBEP00000016728 LOC109979207 LOC109979207 ENSLBEP00000016121 ENSLBEP00000016121 CHD4 CHD4 LOC110004989 LOC110004989 LOC109987876 LOC109987876 pole pole apex2 apex2 chd9 chd9 ENSLBEP00000015384 ENSLBEP00000015384 fto fto rev3l rev3l ENSLBEP00000014993 ENSLBEP00000014993 ENSLBEP00000014904 ENSLBEP00000014904 ENSLBEP00000014884 ENSLBEP00000014884 ENSLBEP00000014847 ENSLBEP00000014847 LOC109979124 LOC109979124 ENSLBEP00000014692 ENSLBEP00000014692 ENSLBEP00000014572 ENSLBEP00000014572 chd2 chd2 ENSLBEP00000014313 ENSLBEP00000014313 LOC110001111 LOC110001111 ercc2 ercc2 ENSLBEP00000013750 ENSLBEP00000013750 ENSLBEP00000013608 ENSLBEP00000013608 rad17 rad17 ENSLBEP00000013531 ENSLBEP00000013531 apex1 apex1 cry1 cry1 LOC109975730 LOC109975730 ENSLBEP00000012752 ENSLBEP00000012752 pms2 pms2 LOC110001643 LOC110001643 poll poll ENSLBEP00000012365 ENSLBEP00000012365 ENSLBEP00000012292 ENSLBEP00000012292 rad9a rad9a LOC109988331 LOC109988331 ENSLBEP00000011994 ENSLBEP00000011994 ENSLBEP00000011963 ENSLBEP00000011963 LOC109996705 LOC109996705 ENSLBEP00000011876 ENSLBEP00000011876 supv3l1 supv3l1 ENSLBEP00000011761 ENSLBEP00000011761 dicer1 dicer1 alkbh4 alkbh4 dna2 dna2 ddx1 ddx1 LOC109993547 LOC109993547 ENSLBEP00000010800 ENSLBEP00000010800 LOC109991260 LOC109991260 ogg1 ogg1 smarcad1 smarcad1 brip1 brip1 MPHOSPH9 MPHOSPH9 spo11 spo11 LOC109996043 LOC109996043 alkbh1 alkbh1 ENSLBEP00000009621 ENSLBEP00000009621 ENSLBEP00000009224 ENSLBEP00000009224 dnase1 dnase1 ENSLBEP00000009084 ENSLBEP00000009084 ENSLBEP00000008927 ENSLBEP00000008927 ENSLBEP00000008890 ENSLBEP00000008890 LOC109992333 LOC109992333 ENSLBEP00000008723 ENSLBEP00000008723 ENSLBEP00000008611 ENSLBEP00000008611 ENSLBEP00000008555 ENSLBEP00000008555 LOC109977506 LOC109977506 ENSLBEP00000008159 ENSLBEP00000008159 lig1 lig1 LOC110001024 LOC110001024 rexo2 rexo2 LOC110004379 LOC110004379 pif1 pif1 mbd4 mbd4 dntt dntt nthl1 nthl1 ENSLBEP00000006652 ENSLBEP00000006652 shprh shprh fancm fancm ruvbl2 ruvbl2 LOC109977420 LOC109977420 ENSLBEP00000005965 ENSLBEP00000005965 ENSLBEP00000005964 ENSLBEP00000005964 dclre1a dclre1a mcm6 mcm6 ENSLBEP00000005682 ENSLBEP00000005682 alkbh3 alkbh3 ENSLBEP00000005381 ENSLBEP00000005381 rfc1 rfc1 LOC109986017 LOC109986017 tdg tdg ENSLBEP00000004864 ENSLBEP00000004864 ENSLBEP00000004858 ENSLBEP00000004858 mgme1 mgme1 ENSLBEP00000004590 ENSLBEP00000004590 smarcal1 smarcal1 rfc3 rfc3 xrcc5 xrcc5 ENSLBEP00000004278 ENSLBEP00000004278 ENSLBEP00000004256 ENSLBEP00000004256 rad54b rad54b top3b top3b ENSLBEP00000003898 ENSLBEP00000003898 ercc6l2 ercc6l2 ENSLBEP00000003862 ENSLBEP00000003862 ENSLBEP00000003852 ENSLBEP00000003852 ENSLBEP00000003714 ENSLBEP00000003714 polh polh xrcc6 xrcc6 ENSLBEP00000003472 ENSLBEP00000003472 LOC109988845 LOC109988845 msh4 msh4 mcm9 mcm9 ENSLBEP00000002562 ENSLBEP00000002562 LOC109993446 LOC109993446 ENSLBEP00000002444 ENSLBEP00000002444 ENSLBEP00000001874 ENSLBEP00000001874 LOC109992266 LOC109992266 dmc1 dmc1 UNG UNG alkbh2 alkbh2 LOC109990949 LOC109990949 ENSLBEP00000000953 ENSLBEP00000000953 ENSLBEP00000000934 ENSLBEP00000000934 mlh3 mlh3 ercc3 ercc3 haus3 haus3 LOC109991226 LOC109991226 gtf2f2 gtf2f2 ENSLBEP00000000442 ENSLBEP00000000442 polg polg ENSLBEP00000000333 ENSLBEP00000000333 MSH2 MSH2 ENSLBEP00000000113 ENSLBEP00000000113 chd1l chd1l xrcc2 xrcc2 LOC110003388 LOC110003388 ino80 ino80 exo1 exo1 LOC110003393 LOC110003393 meiob meiob primpol primpol tatdn1 tatdn1 chd1 chd1 fen1 fen1 ENSLBEP00000033032 ENSLBEP00000033032 ep400 ep400 LOC109991604 LOC109991604 rad50 rad50 RBM20 RBM20 smc3 smc3 bivm bivm ercc4 ercc4 rsf1 rsf1 mre11 mre11 rad51 rad51 LOC110005464 LOC110005464 PLD4 PLD4 btaf1 btaf1 lig3 lig3 rad51d rad51d poli poli atrx atrx LOC109983388 LOC109983388 dnase2b dnase2b
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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msh2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (935 aa)
n6amt1N-6 adenine-specific DNA methyltransferase 1. (215 aa)
top2bDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1491 aa)
hellsHelicase, lymphoid specific. (854 aa)
zranb3Zinc finger, RAN-binding domain containing 3. (1192 aa)
LOC109989370General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (254 aa)
pms1PMS1 homolog 1, mismatch repair system component. (1093 aa)
twnkTwinkle mtDNA helicase. (706 aa)
hltfHelicase-like transcription factor. (938 aa)
LOC110002098Exonuclease 3'-5' domain containing 2. (633 aa)
LOC109980699Chromodomain helicase DNA binding protein 3. (1861 aa)
ENSLBEP00000038445Uncharacterized protein. (434 aa)
ENSLBEP00000038538Uncharacterized protein. (486 aa)
LOC109979646Uncharacterized protein. (342 aa)
ENSLBEP00000038685Uncharacterized protein. (246 aa)
LOC109989976Cryptochrome circadian regulator 1b. (618 aa)
blmATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (846 aa)
LOC109990300RAD54 like 2. (1515 aa)
tdp2Tyrosyl-DNA phosphodiesterase 2b. (360 aa)
LOC109986347Helicase, POLQ like. (964 aa)
dkc1Dyskeratosis congenita 1, dyskerin. (487 aa)
recql5RecQ helicase-like 5. (430 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (899 aa)
LOC110001857ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (954 aa)
LOC109983927SET domain and mariner transposase fusion gene. (299 aa)
ENSLBEP00000025729Reverse transcriptase domain-containing protein. (96 aa)
dffbDNA fragmentation factor, beta polypeptide (caspase-activated DNase). (346 aa)
ddx11DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (910 aa)
LOC109976496Uncharacterized protein. (470 aa)
LOC110005319Deoxyribonuclease-1-like 2. (341 aa)
dnase1l3Deoxyribonuclease; Belongs to the DNase I family. (295 aa)
LOC109993082Cryptochrome DASH. (521 aa)
LOC109983279Si:dkey-119f1.1. (1050 aa)
LOC109994357Uncharacterized protein. (1425 aa)
dnmt1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1416 aa)
chd7Chromodomain helicase DNA binding protein 7. (3294 aa)
rps3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (245 aa)
APTXAprataxin. (340 aa)
ENSLBEP00000028573Zgc:165656. (175 aa)
polkPolymerase (DNA directed) kappa. (395 aa)
mettl4Methyltransferase like 4; Belongs to the MT-A70-like family. (435 aa)
pgbd5PiggyBac transposable element derived 5. (532 aa)
LOC110004773Helicase, POLQ like. (989 aa)
polmDNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (533 aa)
mcm3DNA helicase; Belongs to the MCM family. (813 aa)
dclre1cDNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (671 aa)
ankle1Zgc:85936. (1185 aa)
ENSLBEP00000030170Reverse transcriptase domain-containing protein. (202 aa)
LOC109980655Uncharacterized protein. (112 aa)
LOC109975320SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (766 aa)
LOC109975370Uncharacterized protein. (330 aa)
pold1DNA polymerase. (1126 aa)
dhx36DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1065 aa)
recqlATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (842 aa)
mcm5DNA helicase; Belongs to the MCM family. (738 aa)
fbh1F-box DNA helicase 1. (1069 aa)
tertTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1108 aa)
rad54lRAD54 like. (744 aa)
ENSLBEP00000019134Chromo_2 domain-containing protein. (634 aa)
ENSLBEP00000019263annotation not available (149 aa)
ttf2Transcription termination factor, RNA polymerase II. (1095 aa)
neil3Nei-like DNA glycosylase 3. (558 aa)
rtel1Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1179 aa)
fan1Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (993 aa)
LOC109978422Aprataxin. (345 aa)
ENSLBEP00000020198Helicase C-terminal domain-containing protein. (229 aa)
dclre1bDNA cross-link repair 1B. (612 aa)
endogEndonuclease. (298 aa)
ENSLBEP00000020343MCM_N domain-containing protein. (134 aa)
top2aDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1440 aa)
ENSLBEP00000020439annotation not available (149 aa)
ENSLBEP00000020673RecQ helicase-like 4. (781 aa)
mus81MUS81 structure-specific endonuclease subunit. (496 aa)
knl1Knl1_RWD_C domain-containing protein. (1870 aa)
msh6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1382 aa)
LOC110003012Endo/exonuclease/phosphatase domain-containing protein. (320 aa)
ENSLBEP00000021724Neil1-DNA_bind domain-containing protein. (206 aa)
LOC109976362RAD51 paralog C. (342 aa)
wrnip1WRN helicase interacting protein 1. (496 aa)
LOC110002533RECA_2 domain-containing protein. (354 aa)
ENSLBEP00000022376Helicase ATP-binding domain-containing protein. (181 aa)
pola1DNA polymerase. (1476 aa)
smug1Single-strand-selective monofunctional uracil-DNA glycosylase 1. (276 aa)
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a. (1551 aa)
ENSLBEP00000023018DNA (cytosine-5-)-methyltransferase 3 alpha a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (777 aa)
MUTYHAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (536 aa)
LOC109983919DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (745 aa)
ENSLBEP00000023366Uncharacterized protein. (224 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
rad1RAD1 homolog (S. pombe). (279 aa)
smarca5SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (1034 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1018 aa)
rev1REV1 DNA directed polymerase. (1385 aa)
ENSLBEP00000024278Bromo domain-containing protein. (226 aa)
ENSLBEP00000019089Uncharacterized protein. (202 aa)
LOC109982170Immunoglobulin mu DNA binding protein 2. (973 aa)
ercc6Excision repair cross-complementation group 6. (1440 aa)
lig4DNA ligase. (827 aa)
LOC109985460DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1467 aa)
msh3MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). (1024 aa)
ENSLBEP00000018564Uncharacterized protein. (542 aa)
ENSLBEP00000018189Endo/exonuclease/phosphatase domain-containing protein. (230 aa)
ENSLBEP00000018112Reverse transcriptase domain-containing protein. (208 aa)
SMARCA1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (985 aa)
mlh1MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (648 aa)
ENDOVEndonuclease V. (252 aa)
ENSLBEP00000016945XPGN domain-containing protein. (334 aa)
ENSLBEP00000016887XPGI domain-containing protein. (411 aa)
mpgN-methylpurine DNA glycosylase. (259 aa)
ENSLBEP00000016728Uncharacterized protein. (52 aa)
LOC109979207DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1148 aa)
ENSLBEP00000016121QLQ domain-containing protein. (276 aa)
CHD4Uncharacterized protein. (1996 aa)
LOC110004989HGTP_anticodon domain-containing protein. (458 aa)
LOC109987876DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (747 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2259 aa)
apex2DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (569 aa)
chd9Chromodomain helicase DNA binding protein 9. (2810 aa)
ENSLBEP00000015384Uncharacterized protein. (105 aa)
ftoFTO alpha-ketoglutarate dependent dioxygenase. (654 aa)
rev3lREV3 like, DNA directed polymerase zeta catalytic subunit. (2789 aa)
ENSLBEP00000014993Uncharacterized protein. (99 aa)
ENSLBEP00000014904Uncharacterized protein. (106 aa)
ENSLBEP00000014884annotation not available (155 aa)
ENSLBEP00000014847Uncharacterized protein. (248 aa)
LOC109979124Helicase ATP-binding domain-containing protein. (628 aa)
ENSLBEP00000014692Uncharacterized protein. (200 aa)
ENSLBEP00000014572Endo/exonuclease/phosphatase domain-containing protein. (332 aa)
chd2Chromodomain helicase DNA binding protein 2. (1732 aa)
ENSLBEP00000014313annotation not available (150 aa)
LOC110001111Polymerase (DNA directed), gamma 2, accessory subunit. (454 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
ENSLBEP00000013750Uncharacterized protein. (107 aa)
ENSLBEP00000013608PHD-type domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (615 aa)
rad17RAD17 checkpoint clamp loader component. (618 aa)
ENSLBEP00000013531annotation not available (150 aa)
apex1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (311 aa)
cry1Cryptochrome circadian regulator 1a. (625 aa)
LOC109975730RECA_2 domain-containing protein. (340 aa)
ENSLBEP00000012752Helicase ATP-binding domain-containing protein. (251 aa)
pms2PMS1 homolog 2, mismatch repair system component. (852 aa)
LOC110001643Activating signal cointegrator 1 complex subunit 3. (1848 aa)
pollPolymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (568 aa)
ENSLBEP00000012365Uncharacterized protein. (152 aa)
ENSLBEP00000012292Uncharacterized protein. (619 aa)
rad9aRAD9 checkpoint clamp component A. (372 aa)
LOC109988331CECR2 histone acetyl-lysine reader. (1625 aa)
ENSLBEP00000011994Uncharacterized protein. (147 aa)
ENSLBEP00000011963Uncharacterized protein. (156 aa)
LOC109996705Zgc:66475. (510 aa)
ENSLBEP00000011876Uncharacterized protein. (726 aa)
supv3l1SUV3-like helicase. (786 aa)
ENSLBEP00000011761annotation not available (149 aa)
dicer1Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1910 aa)
alkbh4AlkB homolog 4, lysine demthylase. (273 aa)
dna2DNA replication helicase/nuclease 2. (1384 aa)
ddx1DEAD (Asp-Glu-Ala-Asp) box helicase 1. (648 aa)
LOC109993547Uncharacterized protein. (1255 aa)
ENSLBEP00000010800PHD-type domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (585 aa)
LOC109991260Phospholipase D family, member 3. (484 aa)
ogg18-oxoguanine DNA glycosylase. (385 aa)
smarcad1Uncharacterized protein. (1058 aa)
brip1BRCA1 interacting protein C-terminal helicase 1. (1553 aa)
MPHOSPH9M-phase phosphoprotein 9. (959 aa)
spo11SPO11 initiator of meiotic double stranded breaks. (390 aa)
LOC109996043Zgc:110269. (347 aa)
alkbh1AlkB homolog 1, histone H2A dioxygenase. (370 aa)
ENSLBEP00000009621Uncharacterized protein. (539 aa)
ENSLBEP00000009224MutS homolog 5. (518 aa)
dnase1Deoxyribonuclease I. (322 aa)
ENSLBEP00000009084Uncharacterized protein. (88 aa)
ENSLBEP00000008927Uncharacterized protein. (150 aa)
ENSLBEP00000008890Helicase for meiosis 1. (1073 aa)
LOC109992333DNA topoisomerase I. (594 aa)
ENSLBEP00000008723Reverse transcriptase domain-containing protein. (801 aa)
ENSLBEP00000008611Uncharacterized protein. (151 aa)
ENSLBEP00000008555Uncharacterized protein. (144 aa)
LOC109977506DNA (cytosine-5-)-methyltransferase 3 alpha b; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (997 aa)
ENSLBEP00000008159Uncharacterized protein. (82 aa)
lig1DNA ligase. (767 aa)
LOC110001024DNA helicase; Belongs to the MCM family. (833 aa)
rexo2Small fragment nuclease. (189 aa)
LOC110004379Uncharacterized protein. (341 aa)
pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (614 aa)
mbd4Methyl-CpG binding domain protein 4. (520 aa)
dnttDNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (497 aa)
nthl1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family. (335 aa)
ENSLBEP00000006652TROVE domain-containing protein. (969 aa)
shprhSNF2 histone linker PHD RING helicase. (1523 aa)
fancmUncharacterized protein. (1810 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (492 aa)
LOC109977420Structural maintenance of chromosomes 6. (825 aa)
ENSLBEP00000005965RFC1 domain-containing protein. (117 aa)
ENSLBEP00000005964Reverse transcriptase domain-containing protein. (814 aa)
dclre1aDNA cross-link repair 1A (PSO2 homolog, S. cerevisiae). (871 aa)
mcm6DNA helicase; Belongs to the MCM family. (855 aa)
ENSLBEP00000005682Uncharacterized protein. (1420 aa)
alkbh3AlkB homolog 3, alpha-ketoglutarate-dependent dioxygenase. (294 aa)
ENSLBEP00000005381Uncharacterized protein. (295 aa)
rfc1Replication factor C subunit 1. (1024 aa)
LOC109986017Thymine DNA glycosylase, tandem duplicate 2. (398 aa)
tdgThymine DNA glycosylase, tandem duplicate 1. (454 aa)
ENSLBEP00000004864Reverse transcriptase domain-containing protein. (814 aa)
ENSLBEP00000004858Uncharacterized protein. (481 aa)
mgme1Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family. (328 aa)
ENSLBEP00000004590Uncharacterized protein. (150 aa)
smarcal1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (869 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (724 aa)
ENSLBEP00000004278DEAD domain-containing protein. (155 aa)
ENSLBEP00000004256Uncharacterized protein. (115 aa)
rad54bRAD54 homolog B. (875 aa)
top3bDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (854 aa)
ENSLBEP00000003898DNA_pol_B_thumb domain-containing protein. (54 aa)
ercc6l2Excision repair cross-complementation group 6-like 2. (1581 aa)
ENSLBEP00000003862DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (154 aa)
ENSLBEP00000003852Reverse transcriptase domain-containing protein. (318 aa)
ENSLBEP00000003714Uncharacterized protein. (173 aa)
polhPolymerase (DNA directed), eta. (723 aa)
xrcc6X-ray repair complementing defective repair in Chinese hamster cells 6. (619 aa)
ENSLBEP00000003472Chromo domain-containing protein. (511 aa)
LOC109988845Deoxyribonuclease II, lysosomal. (360 aa)
msh4MutS homolog 4. (821 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1131 aa)
ENSLBEP00000002562Uncharacterized protein. (99 aa)
LOC109993446AAA domain-containing protein. (835 aa)
ENSLBEP00000002444Uncharacterized protein. (289 aa)
ENSLBEP00000001874RAD9 checkpoint clamp component B. (188 aa)
LOC109992266Si:ch211-141o9.10. (328 aa)
dmc1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (332 aa)
UNGUracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (279 aa)
alkbh2AlkB homolog 2, alpha-ketoglutarate-dependent dioxygenase. (234 aa)
LOC109990949Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (335 aa)
ENSLBEP00000000953Uncharacterized protein. (149 aa)
ENSLBEP00000000934Uncharacterized protein. (822 aa)
mlh3MutL_C domain-containing protein. (382 aa)
ercc3Excision repair cross-complementation group 3. (782 aa)
haus3HAUS augmin-like complex, subunit 3. (660 aa)
LOC109991226PHD-type domain-containing protein. (1409 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (292 aa)
ENSLBEP00000000442Polymerase (DNA directed) nu. (772 aa)
polgPolymerase (DNA directed), gamma. (1194 aa)
ENSLBEP00000000333Uncharacterized protein. (270 aa)
MSH2MutS homolog 2. (600 aa)
ENSLBEP00000000113Excision repair cross-complementation group 6-like. (1000 aa)
chd1lChromodomain helicase DNA binding protein 1-like. (1028 aa)
xrcc2RECA_2 domain-containing protein. (304 aa)
LOC110003388Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (265 aa)
ino80INO80 complex ATPase subunit. (1497 aa)
exo1Exonuclease 1. (793 aa)
LOC110003393DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (334 aa)
meiobMethionine sulfoxide reductase B1b. (438 aa)
primpolPrimase and polymerase (DNA-directed). (539 aa)
tatdn1TatD DNase domain containing 1. (314 aa)
chd1Chromodomain helicase DNA binding protein 1. (1741 aa)
fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa)
ENSLBEP00000033032Endo/exonuclease/phosphatase domain-containing protein. (369 aa)
ep400E1A binding protein p400. (2973 aa)
LOC109991604DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (336 aa)
rad50RAD50 homolog, double strand break repair protein. (1284 aa)
RBM20RNA binding motif protein 20. (889 aa)
smc3Structural maintenance of chromosomes protein. (1217 aa)
bivmBasic, immunoglobulin-like variable motif containing. (497 aa)
ercc4Excision repair cross-complementation group 4. (895 aa)
rsf1Remodeling and spacing factor 1b, tandem duplicate 1. (1707 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (641 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
LOC110005464DNA helicase; Belongs to the MCM family. (890 aa)
PLD4Phospholipase D family member 4. (460 aa)
btaf1BTAF1 RNA polymerase II, B-TFIID transcription factor-associated. (1854 aa)
lig3DNA ligase. (1039 aa)
rad51dRAD51 paralog D. (334 aa)
poliPolymerase (DNA directed) iota. (684 aa)
atrxATRX chromatin remodeler. (2243 aa)
LOC109983388Uncharacterized protein. (1499 aa)
dnase2bDeoxyribonuclease II beta. (353 aa)
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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