(11 nodes) Chromosome, telomeric repeat region network (Labrus bergylta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	LOC109988732	TERF1 (TRF1)-interacting nuclear factor 2. (557 aa)
	pot1	Protection of telomeres 1 homolog. (718 aa)
	ENSLBEP00000005132	Telo_bind domain-containing protein. (305 aa)
	ENSLBEP00000006855	HTH myb-type domain-containing protein. (181 aa)
	ENSLBEP00000006873	Uncharacterized protein. (125 aa)
	LOC109989819	Uncharacterized protein. (448 aa)
	stn1	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (365 aa)
	ten1	TEN1 subunit of CST complex. (134 aa)
	terf1	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (370 aa)
	rif1	Replication timing regulatory factor 1. (2650 aa)
	terf2ip	Uncharacterized protein. (736 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000005132	ENSLBEP00000006855	ENSLBEP00000005132	ENSLBEP00000006855	Telo_bind domain-containing protein.	HTH myb-type domain-containing protein.	0.936
ENSLBEP00000005132	ENSLBEP00000006873	ENSLBEP00000005132	ENSLBEP00000006873	Telo_bind domain-containing protein.	Uncharacterized protein.	0.972
ENSLBEP00000005132	LOC109988732	ENSLBEP00000005132	ENSLBEP00000001787	Telo_bind domain-containing protein.	TERF1 (TRF1)-interacting nuclear factor 2.	0.986
ENSLBEP00000005132	LOC109989819	ENSLBEP00000005132	ENSLBEP00000009703	Telo_bind domain-containing protein.	Uncharacterized protein.	0.986
ENSLBEP00000005132	stn1	ENSLBEP00000005132	ENSLBEP00000011975	Telo_bind domain-containing protein.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.799
ENSLBEP00000005132	ten1	ENSLBEP00000005132	ENSLBEP00000013432	Telo_bind domain-containing protein.	TEN1 subunit of CST complex.	0.730
ENSLBEP00000005132	terf1	ENSLBEP00000005132	ENSLBEP00000019249	Telo_bind domain-containing protein.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.970
ENSLBEP00000005132	terf2ip	ENSLBEP00000005132	ENSLBEP00000033300	Telo_bind domain-containing protein.	Uncharacterized protein.	0.969
ENSLBEP00000006855	ENSLBEP00000005132	ENSLBEP00000006855	ENSLBEP00000005132	HTH myb-type domain-containing protein.	Telo_bind domain-containing protein.	0.936
ENSLBEP00000006855	LOC109989819	ENSLBEP00000006855	ENSLBEP00000009703	HTH myb-type domain-containing protein.	Uncharacterized protein.	0.979
ENSLBEP00000006855	pot1	ENSLBEP00000006855	ENSLBEP00000004711	HTH myb-type domain-containing protein.	Protection of telomeres 1 homolog.	0.936
ENSLBEP00000006855	stn1	ENSLBEP00000006855	ENSLBEP00000011975	HTH myb-type domain-containing protein.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.628
ENSLBEP00000006855	ten1	ENSLBEP00000006855	ENSLBEP00000013432	HTH myb-type domain-containing protein.	TEN1 subunit of CST complex.	0.586
ENSLBEP00000006855	terf1	ENSLBEP00000006855	ENSLBEP00000019249	HTH myb-type domain-containing protein.	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.875
ENSLBEP00000006855	terf2ip	ENSLBEP00000006855	ENSLBEP00000033300	HTH myb-type domain-containing protein.	Uncharacterized protein.	0.986
ENSLBEP00000006873	ENSLBEP00000005132	ENSLBEP00000006873	ENSLBEP00000005132	Uncharacterized protein.	Telo_bind domain-containing protein.	0.972
ENSLBEP00000006873	LOC109988732	ENSLBEP00000006873	ENSLBEP00000001787	Uncharacterized protein.	TERF1 (TRF1)-interacting nuclear factor 2.	0.992
ENSLBEP00000006873	LOC109989819	ENSLBEP00000006873	ENSLBEP00000009703	Uncharacterized protein.	Uncharacterized protein.	0.986
ENSLBEP00000006873	pot1	ENSLBEP00000006873	ENSLBEP00000004711	Uncharacterized protein.	Protection of telomeres 1 homolog.	0.972
ENSLBEP00000006873	stn1	ENSLBEP00000006873	ENSLBEP00000011975	Uncharacterized protein.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.706