(65 nodes) Positive regulation of cell junction assembly network (Labrus bergylta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC110000815	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family. (188 aa)
	ENSLBEP00000033076	Uncharacterized protein. (334 aa)
	ENSLBEP00000033897	Uncharacterized protein. (99 aa)
	slitrk4	SLIT and NTRK-like family, member 4. (862 aa)
	LOC109993319	Eukaryotic elongation factor 2 kinase. (709 aa)
	LOC109988663	Protein S100; Belongs to the S-100 family. (100 aa)
	LOC110003590	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
	lrrtm2	Leucine rich repeat transmembrane neuronal 2. (638 aa)
	SYNDIG1	Synapse differentiation inducing 1. (258 aa)
	LOC110004179	Uncharacterized protein. (502 aa)
	cux2	Homeobox protein cut-like. (1350 aa)
	LOC109998532	Leucine rich repeat containing 24. (617 aa)
	ENSLBEP00000002295	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (137 aa)
	dlg5	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1858 aa)
	slitrk5	SLIT and NTRK-like family, member 5a. (875 aa)
	slitrk6	SLIT and NTRK-like family, member 6. (843 aa)
	SLITRK1	SLIT and NTRK like family member 1. (705 aa)
	LOC109988144	Leucine rich repeat neuronal 3b. (709 aa)
	vegfa	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (214 aa)
	cbln1	Cerebellin 1 precursor. (191 aa)
	ENSLBEP00000006763	SLIT and NTRK-like family, member 3a. (912 aa)
	LOC109983653	Fibronectin leucine rich transmembrane protein 2. (660 aa)
	LOC109981964	Neuropilin; Belongs to the neuropilin family. (874 aa)
	LOC109984809	Leucine rich repeat neuronal 3a. (664 aa)
	flrt3	Fibronectin leucine rich transmembrane 3. (651 aa)
	nphp1	Nephronophthisis 1. (675 aa)
	LOC109996245	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	LOC110000499	Interleukin 1 receptor accessory protein-like 1a. (709 aa)
	ENSLBEP00000010675	Uncharacterized protein. (243 aa)
	cldn19	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (222 aa)
	LOC109996624	Eph receptor B3a. (895 aa)
	ENSLBEP00000011962	Ig-like domain-containing protein. (569 aa)
	LRRTM4	Leucine rich repeat transmembrane neuronal 4. (531 aa)
	vstm5	I-set domain-containing protein. (192 aa)
	LOC109980911	Ig-like domain-containing protein. (485 aa)
	LOC109987139	Uncharacterized protein. (1070 aa)
	irx3	Iroquois homeobox 3a. (428 aa)
	LOC109990113	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	LOC110005018	Si:ch211-180f4.1. (718 aa)
	LOC109990139	Ig-like domain-containing protein. (513 aa)
	itgb1bp1	Integrin beta 1 binding protein 1. (200 aa)
	LOC109985580	Agrin. (1838 aa)
	LOC109984310	Uncharacterized protein. (730 aa)
	LOC109991988	Calsyntenin 2. (927 aa)
	lrtm2	Leucine-rich repeats and transmembrane domains 2a. (401 aa)
	LOC109992484	Uncharacterized protein. (674 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (888 aa)
	clstn2	Si:ch211-276c2.2. (947 aa)
	ephb3	Uncharacterized protein. (985 aa)
	ENSLBEP00000025255	Ig-like domain-containing protein. (527 aa)
	lrrn1	Leucine rich repeat neuronal 1. (717 aa)
	LOC109996630	Nephronophthisis 4. (246 aa)
	amigo1	Adhesion molecule with Ig-like domain 1. (512 aa)
	LOC109998312	Fibronectin leucine rich transmembrane protein 2. (642 aa)
	LOC109985666	TSC complex subunit 1b. (1297 aa)
	LOC109985114	Activity-dependent neuroprotector homeobox b. (1061 aa)
	lrrtm1	Leucine rich repeat transmembrane neuronal 1. (525 aa)
	clstn1	Calsyntenin 1. (981 aa)
	slitrk2	SLIT and NTRK-like family, member 2. (768 aa)
	LOC109993823	Ig-like domain-containing protein. (618 aa)
	LOC109981668	Si:dkey-28o19.1. (627 aa)
	LOC109990328	Ig-like domain-containing protein. (788 aa)
	agt	Angiotensinogen; Belongs to the serpin family. (426 aa)
	LOC109995591	Si:dkeyp-74b6.2. (207 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (389 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000002295	LOC109988663	ENSLBEP00000002295	ENSLBEP00000035522	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Protein S100; Belongs to the S-100 family.	0.491
ENSLBEP00000002295	LOC109990113	ENSLBEP00000002295	ENSLBEP00000015571	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.420
ENSLBEP00000002295	LOC109996245	ENSLBEP00000002295	ENSLBEP00000010408	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.875
ENSLBEP00000002295	LOC110003590	ENSLBEP00000002295	ENSLBEP00000036451	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.842
ENSLBEP00000002295	cldn19	ENSLBEP00000002295	ENSLBEP00000011504	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.842
ENSLBEP00000010675	LOC109990113	ENSLBEP00000010675	ENSLBEP00000015571	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.756
ENSLBEP00000010675	LOC109996624	ENSLBEP00000010675	ENSLBEP00000011845	Uncharacterized protein.	Eph receptor B3a.	0.410
ENSLBEP00000010675	ephb3	ENSLBEP00000010675	ENSLBEP00000024511	Uncharacterized protein.	Uncharacterized protein.	0.410
ENSLBEP00000010675	nphp1	ENSLBEP00000010675	ENSLBEP00000009594	Uncharacterized protein.	Nephronophthisis 1.	0.523
ENSLBEP00000033897	LOC109990113	ENSLBEP00000033897	ENSLBEP00000015571	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.420
ENSLBEP00000033897	LOC109996245	ENSLBEP00000033897	ENSLBEP00000010408	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.877
ENSLBEP00000033897	LOC110003590	ENSLBEP00000033897	ENSLBEP00000036451	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.842
ENSLBEP00000033897	cldn19	ENSLBEP00000033897	ENSLBEP00000011504	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.842
LOC109981964	LOC110000815	ENSLBEP00000007426	ENSLBEP00000031981	Neuropilin; Belongs to the neuropilin family.	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family.	0.642
LOC109981964	SEMA4D	ENSLBEP00000007426	ENSLBEP00000024073	Neuropilin; Belongs to the neuropilin family.	Semaphorin 4D; Belongs to the semaphorin family.	0.500
LOC109981964	vegfa	ENSLBEP00000007426	ENSLBEP00000004357	Neuropilin; Belongs to the neuropilin family.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.643
LOC109984310	SLITRK1	ENSLBEP00000019244	ENSLBEP00000004163	Uncharacterized protein.	SLIT and NTRK like family member 1.	0.427
LOC109984310	slitrk2	ENSLBEP00000019244	ENSLBEP00000028368	Uncharacterized protein.	SLIT and NTRK-like family, member 2.	0.407
LOC109985580	LOC110000815	ENSLBEP00000018720	ENSLBEP00000031981	Agrin.	Vascular endothelial growth factor Aa; Belongs to the PDGF/VEGF growth factor family.	0.845
LOC109985580	vegfa	ENSLBEP00000018720	ENSLBEP00000004357	Agrin.	Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.	0.873