(78 nodes) Regulation of response to wounding network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109986051	Uncharacterized protein. (308 aa)
	stil	SERPIN domain-containing protein; Belongs to the serpin family. (1381 aa)
	ENSLBEP00000006879	Calcium/calmodulin-dependent serine protein kinase b. (505 aa)
	ENSLBEP00000006581	Uncharacterized protein. (63 aa)
	LOC109991736	Reticulon 4 receptor-like 1a. (455 aa)
	ENSLBEP00000002728	SERPIN domain-containing protein; Belongs to the serpin family. (185 aa)
	LOC109984039	Uncharacterized protein. (1208 aa)
	ENSLBEP00000017540	Thymosin beta 2. (44 aa)
	ENSLBEP00000031657	Elastin microfibril interfacer 2b. (957 aa)
	FGB	Fibrinogen beta chain. (451 aa)
	c1qtnf1	C1q and TNF related 1. (271 aa)
	cunh5orf30	Zgc:194281. (213 aa)
	CD9	Tetraspanin. (212 aa)
	ENSLBEP00000029050	Thromboxane A2 receptor. (340 aa)
	LOC109999978	Reticulon 4 receptor-like 1b. (452 aa)
	proc	Protein C (inactivator of coagulation factors Va and VIIIa), a. (437 aa)
	LOC109999151	Si:ch211-237i5.4. (345 aa)
	LOC109995105	Uncharacterized protein; Belongs to the MAGUK family. (884 aa)
	ENSLBEP00000037504	LRRCT domain-containing protein. (361 aa)
	serping1	Uncharacterized protein; Belongs to the serpin family. (601 aa)
	LOC109988080	Heparin-binding EGF-like growth factor a. (239 aa)
	LOC110003590	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
	LOC109985865	Parvalbumin 8; Belongs to the parvalbumin family. (128 aa)
	pdgfa	Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family. (227 aa)
	scarf1	Scavenger receptor class F, member 1. (867 aa)
	ptn	Pleiotrophin. (149 aa)
	fermt1	Fermitin family member 1. (665 aa)
	enpp4	Ectonucleotide pyrophosphatase/phosphodiesterase 4. (447 aa)
	LOC110002727	Uncharacterized protein. (668 aa)
	plg	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (812 aa)
	ENSLBEP00000022814	Thymosin beta 4 X-linked. (41 aa)
	sh2b3	SH2B adaptor protein 3. (735 aa)
	LOC109993150	Uncharacterized protein. (286 aa)
	LOC109990231	Uncharacterized protein. (251 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (644 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2492 aa)
	LOC110002470	Fibrinogen beta chain. (493 aa)
	rreb1	Ras responsive element binding protein 1a. (1593 aa)
	LOC109987207	Uncharacterized protein. (227 aa)
	il10	Interleukin 10. (187 aa)
	APOH-2	Uncharacterized protein. (367 aa)
	pros1	Protein S. (679 aa)
	APOH	Uncharacterized protein. (352 aa)
	CASK	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (885 aa)
	wfdc1	WAP four-disulfide core domain 1. (209 aa)
	LOC109990113	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	LOC109991287	Tetraspanin. (228 aa)
	f2	Coagulation factor II (thrombin); Belongs to the peptidase S1 family. (614 aa)
	c1qtnf6	C1q and TNF related 6b. (242 aa)
	ajap1	Adherens junctions associated protein 1. (397 aa)
	LOC109992014	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (556 aa)
	LOC109996964	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (513 aa)
	LOC109991565	Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family. (199 aa)
	LOC109977003	Uncharacterized protein. (351 aa)
	serpine1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (391 aa)
	st3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (339 aa)
	rtn4r	Reticulon 4 receptor. (466 aa)
	cldn19	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (222 aa)
	xbp1	X-box binding protein 1. (264 aa)
	kremen1	Kringle containing transmembrane protein 1. (462 aa)
	LOC109996245	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
	cd34	Si:ch211-286o17.1. (354 aa)
	vegfb	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (297 aa)
	ENSLBEP00000038814	Kringle domain-containing protein. (142 aa)
	ENSLBEP00000038813	Gla domain-containing protein. (95 aa)
	ano6	Anoctamin. (920 aa)
	serpine2	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family. (397 aa)
	LOC110005152	Uncharacterized protein. (228 aa)
	LOC109975219	Uncharacterized protein. (251 aa)
	epha4	Eph receptor A4, like. (989 aa)
	LOC109992143	C-type lectin domain-containing protein. (372 aa)
	myoz1	Uncharacterized protein. (354 aa)
	ENSLBEP00000026961	Uncharacterized protein. (53 aa)
	LOC109998878	SERPIN domain-containing protein; Belongs to the serpin family. (470 aa)
	LOC110004756	Si:ch73-40a2.1. (833 aa)
	ENSLBEP00000028310	EGF-like domain-containing protein. (364 aa)
	ENSLBEP00000028341	Uncharacterized protein. (362 aa)
	serpinf2	SERPIN domain-containing protein; Belongs to the serpin family. (372 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOH	ENSLBEP00000002728	ENSLBEP00000015900	ENSLBEP00000002728	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.821
APOH	ENSLBEP00000038813	ENSLBEP00000015900	ENSLBEP00000038813	Uncharacterized protein.	Gla domain-containing protein.	0.814
APOH	ENSLBEP00000038814	ENSLBEP00000015900	ENSLBEP00000038814	Uncharacterized protein.	Kringle domain-containing protein.	0.814
APOH	FGB	ENSLBEP00000015900	ENSLBEP00000031017	Uncharacterized protein.	Fibrinogen beta chain.	0.620
APOH	LOC109998878	ENSLBEP00000015900	ENSLBEP00000027312	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.569
APOH	LOC110002470	ENSLBEP00000015900	ENSLBEP00000018204	Uncharacterized protein.	Fibrinogen beta chain.	0.620
APOH	f2	ENSLBEP00000015900	ENSLBEP00000015302	Uncharacterized protein.	Coagulation factor II (thrombin); Belongs to the peptidase S1 family.	0.814
APOH	plg	ENSLBEP00000015900	ENSLBEP00000031916	Uncharacterized protein.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.871
APOH	proc	ENSLBEP00000015900	ENSLBEP00000038122	Uncharacterized protein.	Protein C (inactivator of coagulation factors Va and VIIIa), a.	0.610
APOH	serpinf2	ENSLBEP00000015900	ENSLBEP00000028479	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.569
APOH	stil	ENSLBEP00000015900	ENSLBEP00000008011	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.821
APOH-2	ENSLBEP00000002728	ENSLBEP00000015933	ENSLBEP00000002728	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.821
APOH-2	ENSLBEP00000038813	ENSLBEP00000015933	ENSLBEP00000038813	Uncharacterized protein.	Gla domain-containing protein.	0.814
APOH-2	ENSLBEP00000038814	ENSLBEP00000015933	ENSLBEP00000038814	Uncharacterized protein.	Kringle domain-containing protein.	0.814
APOH-2	FGB	ENSLBEP00000015933	ENSLBEP00000031017	Uncharacterized protein.	Fibrinogen beta chain.	0.620
APOH-2	LOC109998878	ENSLBEP00000015933	ENSLBEP00000027312	Uncharacterized protein.	SERPIN domain-containing protein; Belongs to the serpin family.	0.569
APOH-2	LOC110002470	ENSLBEP00000015933	ENSLBEP00000018204	Uncharacterized protein.	Fibrinogen beta chain.	0.620
APOH-2	f2	ENSLBEP00000015933	ENSLBEP00000015302	Uncharacterized protein.	Coagulation factor II (thrombin); Belongs to the peptidase S1 family.	0.814
APOH-2	plg	ENSLBEP00000015933	ENSLBEP00000031916	Uncharacterized protein.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.871
APOH-2	proc	ENSLBEP00000015933	ENSLBEP00000038122	Uncharacterized protein.	Protein C (inactivator of coagulation factors Va and VIIIa), a.	0.610