(12 nodes) Negative regulation of CD4-positive, alpha-beta T cell activation network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109987107	Ring finger and CCCH-type domains 2. (866 aa)
	hlx	H2.0-like homeo box 1 (Drosophila). (358 aa)
	tbx21	T-box transcription factor 21. (616 aa)
	vsir	V-set immunoregulatory receptor. (289 aa)
	LOC109986247	Galectin. (359 aa)
	LOC109985574	E3 ubiquitin-protein ligase. (880 aa)
	LOC109981198	Uncharacterized protein. (506 aa)
	LOC109995561	Ring finger and CCCH-type domains 1b. (1115 aa)
	zc3h12a	Si:dkey-206d17.12. (590 aa)
	LOC109999113	Zinc finger CCCH-type containing 12A. (627 aa)
	LOC109980837	E3 ubiquitin-protein ligase. (867 aa)
	cbfb	Core-binding factor subunit beta. (188 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109980837	cbfb	ENSLBEP00000005882	ENSLBEP00000006631	E3 ubiquitin-protein ligase.	Core-binding factor subunit beta.	0.533
LOC109981198	LOC109986247	ENSLBEP00000031789	ENSLBEP00000021707	Uncharacterized protein.	Galectin.	0.530
LOC109985574	cbfb	ENSLBEP00000021857	ENSLBEP00000006631	E3 ubiquitin-protein ligase.	Core-binding factor subunit beta.	0.533
LOC109986247	LOC109981198	ENSLBEP00000021707	ENSLBEP00000031789	Galectin.	Uncharacterized protein.	0.530
LOC109987107	LOC109995561	ENSLBEP00000006700	ENSLBEP00000028578	Ring finger and CCCH-type domains 2.	Ring finger and CCCH-type domains 1b.	0.860
LOC109995561	LOC109987107	ENSLBEP00000028578	ENSLBEP00000006700	Ring finger and CCCH-type domains 1b.	Ring finger and CCCH-type domains 2.	0.860
LOC109995561	LOC109999113	ENSLBEP00000028578	ENSLBEP00000036669	Ring finger and CCCH-type domains 1b.	Zinc finger CCCH-type containing 12A.	0.420
LOC109995561	zc3h12a	ENSLBEP00000028578	ENSLBEP00000022972	Ring finger and CCCH-type domains 1b.	Si:dkey-206d17.12.	0.420
LOC109999113	LOC109995561	ENSLBEP00000036669	ENSLBEP00000028578	Zinc finger CCCH-type containing 12A.	Ring finger and CCCH-type domains 1b.	0.420
cbfb	LOC109980837	ENSLBEP00000006631	ENSLBEP00000005882	Core-binding factor subunit beta.	E3 ubiquitin-protein ligase.	0.533
cbfb	LOC109985574	ENSLBEP00000006631	ENSLBEP00000021857	Core-binding factor subunit beta.	E3 ubiquitin-protein ligase.	0.533
hlx	tbx21	ENSLBEP00000013002	ENSLBEP00000013757	H2.0-like homeo box 1 (Drosophila).	T-box transcription factor 21.	0.590
tbx21	hlx	ENSLBEP00000013757	ENSLBEP00000013002	T-box transcription factor 21.	H2.0-like homeo box 1 (Drosophila).	0.590
zc3h12a	LOC109995561	ENSLBEP00000022972	ENSLBEP00000028578	Si:dkey-206d17.12.	Ring finger and CCCH-type domains 1b.	0.420