(43 nodes) Negative regulation of extrinsic apoptotic signaling pathway network (Labrus bergylta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	LOC109992227	Fas apoptotic inhibitory molecule a. (198 aa)
	ENSLBEP00000033705	Galectin. (281 aa)
	ENSLBEP00000032852	UBIQUITIN_CONJUGAT_2 domain-containing protein. (192 aa)
	birc6	Baculoviral IAP repeat containing 6. (4000 aa)
	LOC109996231	Tyrosine-protein kinase. (439 aa)
	FGB	Fibrinogen beta chain. (451 aa)
	zc3hc1	Zinc finger, C3HC-type containing 1. (504 aa)
	eya3	Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (606 aa)
	sgk3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (486 aa)
	LOC109975130	Inositol 1,4,5-trisphosphate receptor interacting protein. (530 aa)
	LOC109981070	Uncharacterized protein. (662 aa)
	LOC110002470	Fibrinogen beta chain. (493 aa)
	LOC109981436	Uncharacterized protein. (790 aa)
	LOC109984085	Secretogranin II (chromogranin C), b. (578 aa)
	LOC109983356	Ring finger protein 34a. (363 aa)
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (867 aa)
	rb1cc1	RB1-inducible coiled-coil 1. (1620 aa)
	gclc	Glutamate-cysteine ligase, catalytic subunit. (630 aa)
	cflar	Uncharacterized protein; Belongs to the peptidase C14A family. (445 aa)
	pea15	Proliferation and apoptosis adaptor protein 15. (130 aa)
	SRC	Tyrosine-protein kinase. (549 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	ITPRIP	Inositol 1,4,5-trisphosphate receptor interacting protein. (490 aa)
	ENSLBEP00000005272	Uncharacterized protein. (339 aa)
	brca1	Uncharacterized protein. (1180 aa)
	LOC109976611	Unc-5 netrin receptor B. (734 aa)
	ENSLBEP00000026903	Ring finger protein 34b. (348 aa)
	LOC110003091	Galectin. (296 aa)
	map2k5	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (449 aa)
	LOC109983926	GATA binding protein 1a. (421 aa)
	ENSLBEP00000023548	Uncharacterized protein. (250 aa)
	scg2	Uncharacterized protein. (608 aa)
	LOC109975844	Uncharacterized protein. (449 aa)
	ENSLBEP00000016916	Galectin. (136 aa)
	il1b	Interleukin-1. (251 aa)
	LOC109994731	Uncharacterized protein. (181 aa)
	htt	Huntingtin. (3002 aa)
	psme3	Proteasome activator subunit 3. (267 aa)
	ENSLBEP00000013241	Mab-21 domain-containing protein. (482 aa)
	serpine1	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (391 aa)
	gclm	Glutamate-cysteine ligase, modifier subunit. (277 aa)
	ENSLBEP00000037371	FZ domain-containing protein. (284 aa)
	LOC110002049	Zinc finger, MYND-type containing 11. (526 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000005272	LOC109981070	ENSLBEP00000005272	ENSLBEP00000018998	Uncharacterized protein.	Uncharacterized protein.	0.852
ENSLBEP00000005272	LOC109996231	ENSLBEP00000005272	ENSLBEP00000031227	Uncharacterized protein.	Tyrosine-protein kinase.	0.412
ENSLBEP00000005272	SRC	ENSLBEP00000005272	ENSLBEP00000004031	Uncharacterized protein.	Tyrosine-protein kinase.	0.412
ENSLBEP00000005272	brca1	ENSLBEP00000005272	ENSLBEP00000007044	Uncharacterized protein.	Uncharacterized protein.	0.508
ENSLBEP00000005272	htt	ENSLBEP00000005272	ENSLBEP00000015092	Uncharacterized protein.	Huntingtin.	0.424
ENSLBEP00000032852	LOC109996231	ENSLBEP00000032852	ENSLBEP00000031227	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Tyrosine-protein kinase.	0.583
ENSLBEP00000032852	SRC	ENSLBEP00000032852	ENSLBEP00000004031	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Tyrosine-protein kinase.	0.583
ENSLBEP00000032852	birc6	ENSLBEP00000032852	ENSLBEP00000032814	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Baculoviral IAP repeat containing 6.	0.993
ENSLBEP00000032852	brca1	ENSLBEP00000032852	ENSLBEP00000007044	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.550
ENSLBEP00000032852	cflar	ENSLBEP00000032852	ENSLBEP00000002719	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.849
ENSLBEP00000032852	pea15	ENSLBEP00000032852	ENSLBEP00000002839	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Proliferation and apoptosis adaptor protein 15.	0.834
ENSLBEP00000032852	psme3	ENSLBEP00000032852	ENSLBEP00000014027	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Proteasome activator subunit 3.	0.676
ENSLBEP00000032852	tnfaip3	ENSLBEP00000032852	ENSLBEP00000029916	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Tumor necrosis factor, alpha-induced protein 3.	0.479
FGB	map2k5	ENSLBEP00000031017	ENSLBEP00000024901	Fibrinogen beta chain.	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.	0.571
FGB	serpine1	ENSLBEP00000031017	ENSLBEP00000012870	Fibrinogen beta chain.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.	0.547
LOC109976611	LOC109996231	ENSLBEP00000028693	ENSLBEP00000031227	Unc-5 netrin receptor B.	Tyrosine-protein kinase.	0.719
LOC109976611	SRC	ENSLBEP00000028693	ENSLBEP00000004031	Unc-5 netrin receptor B.	Tyrosine-protein kinase.	0.719
LOC109981070	ENSLBEP00000005272	ENSLBEP00000018998	ENSLBEP00000005272	Uncharacterized protein.	Uncharacterized protein.	0.852
LOC109981070	LOC109981436	ENSLBEP00000018998	ENSLBEP00000007964	Uncharacterized protein.	Uncharacterized protein.	0.835
LOC109981070	LOC109996231	ENSLBEP00000018998	ENSLBEP00000031227	Uncharacterized protein.	Tyrosine-protein kinase.	0.414