(19 nodes) Rough endoplasmic reticulum membrane network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	srpra	SRP receptor subunit alpha. (651 aa)
	sec63	SEC63 homolog, protein translocation regulator. (754 aa)
	tmem97	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins. (170 aa)
	maco1	Macoilin 1b. (687 aa)
	ssr4	Signal sequence receptor, delta. (168 aa)
	LOC109983902	Plug_translocon domain-containing protein. (476 aa)
	SEC61A1	Plug_translocon domain-containing protein. (476 aa)
	rps26	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (115 aa)
	sec61b	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (94 aa)
	ccdc47	Coiled-coil domain containing 47. (341 aa)
	ENSLBEP00000018114	Macoilin 1a. (646 aa)
	rps28	Ribosomal protein S28. (53 aa)
	sec62	SEC62 homolog, preprotein translocation factor. (438 aa)
	epm2a	EPM2A glucan phosphatase, laforin. (316 aa)
	LOC109989687	Si:dkey-12h9.6. (645 aa)
	LOC109979846	SRP receptor subunit beta. (275 aa)
	arl6ip1	ADP-ribosylation factor-like 6 interacting protein 1. (282 aa)
	RPS29	Ribosomal protein S29. (74 aa)
	rps15a	Ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family. (130 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109979846	LOC109983902	ENSLBEP00000028354	ENSLBEP00000020572	SRP receptor subunit beta.	Plug_translocon domain-containing protein.	0.724
LOC109979846	SEC61A1	ENSLBEP00000028354	ENSLBEP00000022861	SRP receptor subunit beta.	Plug_translocon domain-containing protein.	0.724
LOC109979846	sec61b	ENSLBEP00000028354	ENSLBEP00000003078	SRP receptor subunit beta.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.622
LOC109979846	sec62	ENSLBEP00000028354	ENSLBEP00000017491	SRP receptor subunit beta.	SEC62 homolog, preprotein translocation factor.	0.549
LOC109979846	sec63	ENSLBEP00000028354	ENSLBEP00000012040	SRP receptor subunit beta.	SEC63 homolog, protein translocation regulator.	0.678
LOC109979846	srpra	ENSLBEP00000028354	ENSLBEP00000012506	SRP receptor subunit beta.	SRP receptor subunit alpha.	0.998
LOC109979846	ssr4	ENSLBEP00000028354	ENSLBEP00000019348	SRP receptor subunit beta.	Signal sequence receptor, delta.	0.444
LOC109983902	LOC109979846	ENSLBEP00000020572	ENSLBEP00000028354	Plug_translocon domain-containing protein.	SRP receptor subunit beta.	0.724
LOC109983902	RPS29	ENSLBEP00000020572	ENSLBEP00000032528	Plug_translocon domain-containing protein.	Ribosomal protein S29.	0.975
LOC109983902	arl6ip1	ENSLBEP00000020572	ENSLBEP00000030404	Plug_translocon domain-containing protein.	ADP-ribosylation factor-like 6 interacting protein 1.	0.988
LOC109983902	ccdc47	ENSLBEP00000020572	ENSLBEP00000005782	Plug_translocon domain-containing protein.	Coiled-coil domain containing 47.	0.905
LOC109983902	rps15a	ENSLBEP00000020572	ENSLBEP00000036454	Plug_translocon domain-containing protein.	Ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family.	0.988
LOC109983902	rps26	ENSLBEP00000020572	ENSLBEP00000024990	Plug_translocon domain-containing protein.	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.733
LOC109983902	rps28	ENSLBEP00000020572	ENSLBEP00000017564	Plug_translocon domain-containing protein.	Ribosomal protein S28.	0.798
LOC109983902	sec61b	ENSLBEP00000020572	ENSLBEP00000003078	Plug_translocon domain-containing protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.994
LOC109983902	sec62	ENSLBEP00000020572	ENSLBEP00000017491	Plug_translocon domain-containing protein.	SEC62 homolog, preprotein translocation factor.	0.962
LOC109983902	sec63	ENSLBEP00000020572	ENSLBEP00000012040	Plug_translocon domain-containing protein.	SEC63 homolog, protein translocation regulator.	0.999
LOC109983902	srpra	ENSLBEP00000020572	ENSLBEP00000012506	Plug_translocon domain-containing protein.	SRP receptor subunit alpha.	0.986
LOC109983902	ssr4	ENSLBEP00000020572	ENSLBEP00000019348	Plug_translocon domain-containing protein.	Signal sequence receptor, delta.	0.882
RPS29	LOC109983902	ENSLBEP00000032528	ENSLBEP00000020572	Ribosomal protein S29.	Plug_translocon domain-containing protein.	0.975