(45 nodes) Presynaptic active zone network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nptn	Neuroplastin b. (394 aa)
	LOC109984025	Unc-13 homolog A. (1562 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1648 aa)
	rims3	Regulating synaptic membrane exocytosis 3. (324 aa)
	LOC109977797	Syntaxin 11a; Belongs to the syntaxin family. (293 aa)
	LOC109978224	t-SNARE coiled-coil homology domain-containing protein. (294 aa)
	zzef1	Zinc finger, ZZ-type with EF hand domain 1. (2851 aa)
	ENSLBEP00000010244	C2 domain-containing protein. (226 aa)
	erc1	ELKS/RAB6-interacting/CAST family member 1a. (1133 aa)
	stx3	Syntaxin 3A; Belongs to the syntaxin family. (294 aa)
	LOC109995936	Syntaxin 4; Belongs to the syntaxin family. (297 aa)
	UNC13C	Unc-13 homolog C. (2098 aa)
	LOC110000539	Si:cabz01090165.1. (604 aa)
	LOC109994200	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
	LOC109998683	Piccolo presynaptic cytomatrix protein a. (2621 aa)
	ENSLBEP00000019157	Uncharacterized protein. (83 aa)
	ENSLBEP00000019755	Uncharacterized protein. (274 aa)
	LOC109998029	ELKS/RAB6-interacting/CAST family member 1. (1188 aa)
	ENSLBEP00000021028	SynN domain-containing protein. (193 aa)
	LOC109989139	Uncharacterized protein. (1460 aa)
	RIMS1	Regulating synaptic membrane exocytosis 1. (1422 aa)
	LOC109982784	Uncharacterized protein. (1584 aa)
	cplx3	Complexin 3b. (156 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (910 aa)
	LOC109988478	Zgc:172282. (693 aa)
	erc2	ELKS/RAB6-interacting/CAST family member 2. (1152 aa)
	LOC109990294	Bassoon (presynaptic cytomatrix protein) b. (3089 aa)
	LOC110003064	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (257 aa)
	LOC109996638	Uncharacterized protein. (3694 aa)
	STX11	Syntaxin 11; Belongs to the syntaxin family. (300 aa)
	LOC109996130	Uncharacterized protein. (1147 aa)
	LOC109998863	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1107 aa)
	LOC110002613	Syntaxin 1B; Belongs to the syntaxin family. (302 aa)
	unc13b	Uncharacterized protein. (1546 aa)
	LOC109985770	Syntaxin 1A (brain); Belongs to the syntaxin family. (323 aa)
	PCLO	Piccolo presynaptic cytomatrix protein. (4666 aa)
	ENSLBEP00000031587	C2 domain-containing protein. (276 aa)
	LOC109993917	Uncharacterized protein. (1240 aa)
	LOC109983340	Syntaxin 2b; Belongs to the syntaxin family. (293 aa)
	LOC109981697	Fer-1 like family member 4. (1897 aa)
	ENSLBEP00000035528	Uncharacterized protein. (314 aa)
	STX19	Syntaxin 19. (302 aa)
	CDH2-2	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (915 aa)
	nectin1	Nectin cell adhesion molecule 1b. (499 aa)
	LOC110002092	Si:ch211-132f19.7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1154 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	CDH2-2	ENSLBEP00000023804	ENSLBEP00000037704	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.840
CDH2-2	CDH2	ENSLBEP00000037704	ENSLBEP00000023804	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.840
ENSLBEP00000010244	ENSLBEP00000019755	ENSLBEP00000010244	ENSLBEP00000019755	C2 domain-containing protein.	Uncharacterized protein.	0.491
ENSLBEP00000010244	ENSLBEP00000031587	ENSLBEP00000010244	ENSLBEP00000031587	C2 domain-containing protein.	C2 domain-containing protein.	0.495
ENSLBEP00000010244	ENSLBEP00000035528	ENSLBEP00000010244	ENSLBEP00000035528	C2 domain-containing protein.	Uncharacterized protein.	0.733
ENSLBEP00000010244	LOC109982784	ENSLBEP00000010244	ENSLBEP00000023407	C2 domain-containing protein.	Uncharacterized protein.	0.733
ENSLBEP00000010244	LOC109984025	ENSLBEP00000010244	ENSLBEP00000001422	C2 domain-containing protein.	Unc-13 homolog A.	0.733
ENSLBEP00000010244	LOC109989139	ENSLBEP00000010244	ENSLBEP00000022248	C2 domain-containing protein.	Uncharacterized protein.	0.733
ENSLBEP00000010244	LOC109996130	ENSLBEP00000010244	ENSLBEP00000025527	C2 domain-containing protein.	Uncharacterized protein.	0.491
ENSLBEP00000010244	LOC109998029	ENSLBEP00000010244	ENSLBEP00000019797	C2 domain-containing protein.	ELKS/RAB6-interacting/CAST family member 1.	0.491
ENSLBEP00000010244	RIMS2	ENSLBEP00000010244	ENSLBEP00000002860	C2 domain-containing protein.	Regulating synaptic membrane exocytosis 2.	0.469
ENSLBEP00000010244	UNC13C	ENSLBEP00000010244	ENSLBEP00000012431	C2 domain-containing protein.	Unc-13 homolog C.	0.733
ENSLBEP00000010244	erc1	ENSLBEP00000010244	ENSLBEP00000011401	C2 domain-containing protein.	ELKS/RAB6-interacting/CAST family member 1a.	0.491
ENSLBEP00000010244	erc2	ENSLBEP00000010244	ENSLBEP00000024291	C2 domain-containing protein.	ELKS/RAB6-interacting/CAST family member 2.	0.491
ENSLBEP00000010244	unc13b	ENSLBEP00000010244	ENSLBEP00000028541	C2 domain-containing protein.	Uncharacterized protein.	0.733
ENSLBEP00000019157	ENSLBEP00000031587	ENSLBEP00000019157	ENSLBEP00000031587	Uncharacterized protein.	C2 domain-containing protein.	0.716
ENSLBEP00000019157	ENSLBEP00000035528	ENSLBEP00000019157	ENSLBEP00000035528	Uncharacterized protein.	Uncharacterized protein.	0.558
ENSLBEP00000019157	LOC109982784	ENSLBEP00000019157	ENSLBEP00000023407	Uncharacterized protein.	Uncharacterized protein.	0.624
ENSLBEP00000019157	LOC109984025	ENSLBEP00000019157	ENSLBEP00000001422	Uncharacterized protein.	Unc-13 homolog A.	0.624
ENSLBEP00000019157	LOC109989139	ENSLBEP00000019157	ENSLBEP00000022248	Uncharacterized protein.	Uncharacterized protein.	0.624