(48 nodes) Ciliary membrane network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	evc	Uncharacterized protein. (966 aa)
	LOC109981901	Cadherin-related family member 1a. (851 aa)
	EVC2	EvC ciliary complex subunit 2. (1341 aa)
	ENSLBEP00000000242	Septin 4a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (367 aa)
	PDE6C	Phosphodiesterase. (885 aa)
	ENSLBEP00000015105	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (291 aa)
	LOC110004187	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (439 aa)
	LOC109989346	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (204 aa)
	tmem231	Transmembrane protein 231. (307 aa)
	dhrs3	Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
	LOC109988036	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (361 aa)
	LOC110002784	Uncharacterized protein. (75 aa)
	LOC110002783	Phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a. (73 aa)
	septin5	Septin 5a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (376 aa)
	LOC109996756	Uncharacterized protein. (93 aa)
	LOC109985874	Uncharacterized protein. (167 aa)
	LOC109991545	Synaptosome associated protein 29. (260 aa)
	pde6g	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b. (87 aa)
	LOC109981176	Phosphodiesterase. (845 aa)
	LOC109995104	Phosphodiesterase 6H. (133 aa)
	bicc1	BicC family RNA binding protein 1a. (976 aa)
	gpr157	G protein-coupled receptor 157. (335 aa)
	bbs4	Bardet-Biedl syndrome 4. (533 aa)
	LOC110003021	Sulfotransferase; Belongs to the sulfotransferase 1 family. (398 aa)
	bbs5	Bardet-Biedl syndrome 5 protein homolog; Required for ciliogenesis; Belongs to the BBS5 family. (342 aa)
	pkd2	Polycystic kidney disease 2. (903 aa)
	efcab7	EF-hand calcium binding domain 7. (630 aa)
	arl13b	ADP-ribosylation factor-like 13b. (410 aa)
	LOC109999425	Polycystic kidney disease 2-like 1. (783 aa)
	pde6b	Phosphodiesterase. (864 aa)
	ARL6	ADP-ribosylation factor-like 6; Belongs to the small GTPase superfamily. Arf family. (198 aa)
	LOC109986056	Transmembrane protein 17A-like. (204 aa)
	CDHR1	Cadherin related family member 1. (844 aa)
	LOC110000507	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
	ENSLBEP00000010156	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b. (84 aa)
	pde6c	Phosphodiesterase. (841 aa)
	LOC110006045	Uncharacterized protein. (86 aa)
	LOC109975624	Uncharacterized protein. (222 aa)
	LOC109995270	NIPA like domain containing 4. (389 aa)
	LOC109976837	Uncharacterized protein. (278 aa)
	bbs2	Bardet-Biedl syndrome 2 protein homolog. (708 aa)
	LOC109985428	EH-domain containing 1a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (532 aa)
	tmem17	Transmembrane protein 17. (186 aa)
	LOC109988863	Zgc:101583. (358 aa)
	LOC109978860	Synaptosome associated protein 29. (250 aa)
	LOC109987702	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
	LOC109990494	Bicaudal C homolog 2. (779 aa)
	LOC110001508	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma-like. (86 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL6	LOC109999425	ENSLBEP00000014025	ENSLBEP00000016825	ADP-ribosylation factor-like 6; Belongs to the small GTPase superfamily. Arf family.	Polycystic kidney disease 2-like 1.	0.446
ARL6	arl13b	ENSLBEP00000014025	ENSLBEP00000018991	ADP-ribosylation factor-like 6; Belongs to the small GTPase superfamily. Arf family.	ADP-ribosylation factor-like 13b.	0.586
ARL6	bbs2	ENSLBEP00000014025	ENSLBEP00000006487	ADP-ribosylation factor-like 6; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 2 protein homolog.	0.785
ARL6	bbs4	ENSLBEP00000014025	ENSLBEP00000023312	ADP-ribosylation factor-like 6; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 4.	0.780
ARL6	bbs5	ENSLBEP00000014025	ENSLBEP00000022190	ADP-ribosylation factor-like 6; Belongs to the small GTPase superfamily. Arf family.	Bardet-Biedl syndrome 5 protein homolog; Required for ciliogenesis; Belongs to the BBS5 family.	0.539
ARL6	pkd2	ENSLBEP00000014025	ENSLBEP00000021618	ADP-ribosylation factor-like 6; Belongs to the small GTPase superfamily. Arf family.	Polycystic kidney disease 2.	0.446
ENSLBEP00000000242	LOC109988036	ENSLBEP00000000242	ENSLBEP00000035553	Septin 4a; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.841
ENSLBEP00000010156	ENSLBEP00000015105	ENSLBEP00000010156	ENSLBEP00000015105	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.734
ENSLBEP00000010156	LOC109981176	ENSLBEP00000010156	ENSLBEP00000031458	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Phosphodiesterase.	0.953
ENSLBEP00000010156	LOC109987702	ENSLBEP00000010156	ENSLBEP00000004288	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.734
ENSLBEP00000010156	LOC109995104	ENSLBEP00000010156	ENSLBEP00000029513	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Phosphodiesterase 6H.	0.849
ENSLBEP00000010156	LOC109996756	ENSLBEP00000010156	ENSLBEP00000033627	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Uncharacterized protein.	0.682
ENSLBEP00000010156	LOC110000507	ENSLBEP00000010156	ENSLBEP00000011087	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.734
ENSLBEP00000010156	LOC110001508	ENSLBEP00000010156	ENSLBEP00000037975	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma-like.	0.708
ENSLBEP00000010156	LOC110002783	ENSLBEP00000010156	ENSLBEP00000034818	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a.	0.835
ENSLBEP00000010156	LOC110002784	ENSLBEP00000010156	ENSLBEP00000034837	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Uncharacterized protein.	0.835
ENSLBEP00000010156	LOC110006045	ENSLBEP00000010156	ENSLBEP00000007975	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Uncharacterized protein.	0.708
ENSLBEP00000010156	PDE6C	ENSLBEP00000010156	ENSLBEP00000000063	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Phosphodiesterase.	0.900
ENSLBEP00000010156	pde6b	ENSLBEP00000010156	ENSLBEP00000015953	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Phosphodiesterase.	0.958
ENSLBEP00000010156	pde6c	ENSLBEP00000010156	ENSLBEP00000008342	Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.	Phosphodiesterase.	0.900