(186 nodes) Serine-threonine/tyrosine-protein kinase, catalytic domain network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fgfr2	Fibroblast growth factor receptor. (836 aa)
	LOC109984951	Erb-b2 receptor tyrosine kinase 3b. (1458 aa)
	LOC110004968	Guanylate cyclase. (853 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1010 aa)
	igf1r	Tyrosine-protein kinase receptor. (1417 aa)
	fyn	Tyrosine-protein kinase. (482 aa)
	ENSLBEP00000014096	Eph receptor A6; Belongs to the protein kinase superfamily. Tyr protein kinase family. (375 aa)
	ddr1	Discoidin domain receptor tyrosine kinase 1. (1005 aa)
	LOC109997596	Tyrosine-protein kinase. (507 aa)
	frk	Tyrosine-protein kinase. (522 aa)
	LOC109986762	Mitogen-activated protein kinase kinase kinase. (830 aa)
	LOC109999952	Discoidin domain receptor family, member 2, like. (842 aa)
	ENSLBEP00000012879	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (294 aa)
	LOC109997574	Discoidin domain receptor tyrosine kinase 2b. (786 aa)
	ptk6	Tyrosine-protein kinase. (530 aa)
	epha7	Eph receptor A7. (992 aa)
	LOC109996624	Eph receptor B3a. (895 aa)
	epha8	Uncharacterized protein. (1021 aa)
	ksr2	Kinase suppressor of ras 2. (897 aa)
	LOC109989501	Protein kinase domain-containing protein. (505 aa)
	ENSLBEP00000010603	Si:ch211-167j9.5. (396 aa)
	LOC109985452	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1309 aa)
	LOC109999319	Uncharacterized protein. (923 aa)
	LOC109984174	Receptor protein-tyrosine kinase. (742 aa)
	LOC109982009	Fibroblast growth factor receptor. (835 aa)
	raf1	Raf-1 proto-oncogene, serine/threonine kinase a. (657 aa)
	LOC109975378	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (988 aa)
	tesk1	Si:dkeyp-75h12.2. (521 aa)
	LOC109981806	Guanylate cyclase. (1009 aa)
	ksr1	Kinase suppressor of ras 1a. (984 aa)
	insr	Tyrosine-protein kinase receptor. (1364 aa)
	jak1	Tyrosine-protein kinase. (1307 aa)
	LOC109990532	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
	LOC109995813	Fibroblast growth factor receptor 3. (306 aa)
	ephb2	Eph receptor B2b. (988 aa)
	LOC109987794	Tyrosine-protein kinase receptor. (1276 aa)
	ddr2	Discoidin domain receptor tyrosine kinase 2a. (854 aa)
	MLKL	Mixed lineage kinase domain like pseudokinase. (446 aa)
	abl2	Tyrosine-protein kinase. (1213 aa)
	acvr2a	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
	LOC109992329	Protein kinase domain-containing protein. (532 aa)
	LOC109982597	Tyrosine-protein kinase. (458 aa)
	LOC109997465	Testis associated actin remodelling kinase 2. (626 aa)
	LOC109976786	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (351 aa)
	btk	Tyrosine-protein kinase. (615 aa)
	ILK	Integrin linked kinase. (452 aa)
	LOC110005576	Tyrosine-protein kinase. (451 aa)
	LOC110002308	Guanylate cyclase. (1046 aa)
	ENSLBEP00000004327	Protein kinase domain-containing protein. (192 aa)
	ENSLBEP00000004314	Protein kinase domain-containing protein. (82 aa)
	map3k13	Mitogen-activated protein kinase kinase kinase. (1013 aa)
	SRC	Tyrosine-protein kinase. (549 aa)
	LOC109983557	Eph receptor B4a. (985 aa)
	met	MET proto-oncogene, receptor tyrosine kinase. (1423 aa)
	LOC109998569	C-mer proto-oncogene tyrosine kinase a. (901 aa)
	LOC109993468	Uncharacterized protein. (981 aa)
	LOC109984106	Protein kinase domain-containing protein. (670 aa)
	LOC110000365	Tyrosine-protein kinase. (1111 aa)
	LOC109985365	Receptor protein-tyrosine kinase. (1205 aa)
	LOC109982423	Tyrosine-protein kinase. (582 aa)
	LOC109984027	Eph receptor A4b. (985 aa)
	LOC109984039	Uncharacterized protein. (1208 aa)
	ntrk1	Tyrosine-protein kinase receptor. (801 aa)
	LOC109987710	Tyrosine-protein kinase. (537 aa)
	LOC109992272	Guanylate cyclase. (1077 aa)
	ENSLBEP00000002303	Tyrosine-protein kinase receptor. (588 aa)
	ptk2b	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (993 aa)
	LOC109989354	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (534 aa)
	LOC109994136	A-Raf proto-oncogene, serine/threonine kinase. (609 aa)
	LOC110002204	Tyrosine-protein kinase receptor. (798 aa)
	bmpr1a	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
	LOC109993671	Zgc:113162. (331 aa)
	ENSLBEP00000000381	Protein kinase domain-containing protein. (76 aa)
	LOC109992796	KIT proto-oncogene, receptor tyrosine kinase b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (944 aa)
	LOC109987579	Tyrosine-protein kinase. (537 aa)
	LOC109988057	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1382 aa)
	LOC109989372	EPH receptor A6. (986 aa)
	NEK3	NIMA related kinase 3; Belongs to the protein kinase superfamily. (285 aa)
	ENSLBEP00000037129	Protein kinase domain-containing protein. (218 aa)
	epha3	Eph receptor A3. (953 aa)
	LOC109992605	Colony stimulating factor 1 receptor, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (944 aa)
	pdgfrb	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1106 aa)
	LOC110001446	Apoptosis-associated tyrosine kinase b. (1580 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (555 aa)
	hck	HCK proto-oncogene, Src family tyrosine kinase. (315 aa)
	nek7	NIMA-related kinase 7; Belongs to the protein kinase superfamily. (303 aa)
	LOC110002022	Guanylate cyclase. (1102 aa)
	lmtk2	Lemur tyrosine kinase 2. (1541 aa)
	LOC109995062	Guanylate cyclase. (836 aa)
	ryk	Receptor like tyrosine kinase. (630 aa)
	LOC110001353	Tyrosine-protein kinase. (582 aa)
	LOC109999062	Guanylate cyclase. (1076 aa)
	map3k7	Mitogen-activated protein kinase kinase kinase 7. (602 aa)
	limk1	LIM domain kinase 1a. (670 aa)
	LOC109984498	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1005 aa)
	tnk1	Tyrosine kinase, non-receptor, 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (789 aa)
	LOC109993294	Guanylate cyclase. (1147 aa)
	LOC109991634	Tyrosine-protein kinase. (1116 aa)
	tec	Tyrosine-protein kinase. (646 aa)
	ENSLBEP00000033587	TXK tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (237 aa)
	syk	Non-specific protein-tyrosine kinase. (640 aa)
	npr1	Guanylate cyclase. (1060 aa)
	ror2	Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (936 aa)
	tyro3	TYRO3 protein tyrosine kinase. (652 aa)
	LOC109992167	B-Raf proto-oncogene, serine/threonine kinase. (765 aa)
	LOC109981196	Tyrosine-protein kinase. (1130 aa)
	ENSLBEP00000000362	Tyrosine-protein kinase. (265 aa)
	LOC109985151	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (714 aa)
	fes	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (828 aa)
	LOC109996231	Tyrosine-protein kinase. (439 aa)
	nek6	NIMA-related kinase 6; Belongs to the protein kinase superfamily. (310 aa)
	ENSLBEP00000030539	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (524 aa)
	ENSLBEP00000030498	SAM domain-containing protein. (165 aa)
	LOC110000232	Tyrosine-protein kinase receptor. (708 aa)
	ENSLBEP00000029904	Eph receptor A2 a. (922 aa)
	LOC109995558	EPH receptor B1. (1007 aa)
	erbb2	Receptor protein-tyrosine kinase. (1305 aa)
	LOC109994067	Apoptosis-associated tyrosine kinase a. (1633 aa)
	LOC109986311	Uncharacterized protein. (1013 aa)
	LOC109997179	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (682 aa)
	LOC109996168	Tyrosine-protein kinase receptor. (1531 aa)
	MUSK	Muscle associated receptor tyrosine kinase. (821 aa)
	LOC109980643	Macrophage stimulating 1 receptor a. (1394 aa)
	LOC110004756	Si:ch73-40a2.1. (833 aa)
	LOC109992267	Receptor protein-tyrosine kinase. (1184 aa)
	LOC109997830	Uncharacterized protein. (902 aa)
	map3k10	Mitogen-activated protein kinase kinase kinase. (957 aa)
	fer	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (816 aa)
	pdgfra	Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1463 aa)
	LOC109990866	Tyrosine-protein kinase receptor. (1779 aa)
	kit	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (983 aa)
	kdr	Kinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1346 aa)
	LOC109989158	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
	LOC109990836	Mitogen-activated protein kinase kinase kinase. (1035 aa)
	ENSLBEP00000025967	Mitogen-activated protein kinase kinase kinase. (891 aa)
	LOC109986872	Testis associated actin remodelling kinase 1. (731 aa)
	ENSLBEP00000025917	Tyrosine-protein kinase receptor. (558 aa)
	tnk2	Tyrosine kinase, non-receptor, 2b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1192 aa)
	ankk1	Ankyrin repeat and kinase domain containing 1. (756 aa)
	abl1	Tyrosine-protein kinase. (1132 aa)
	LOC109993736	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
	epha2	Eph receptor A2 b. (1039 aa)
	erbb3	Protein kinase domain-containing protein. (1408 aa)
	mst1r	Macrophage stimulating 1 receptor b. (1370 aa)
	ephb3	Uncharacterized protein. (985 aa)
	npr2	Guanylate cyclase. (1049 aa)
	LOC109992111	Guanylate cyclase. (1102 aa)
	epha4	Eph receptor A4, like. (989 aa)
	LOC110000123	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1033 aa)
	ENSLBEP00000023602	Protein kinase domain-containing protein. (170 aa)
	LOC109981135	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (534 aa)
	LOC109996073	TNNI3 interacting kinase. (771 aa)
	CSK	Tyrosine-protein kinase. (357 aa)
	LOC109993160	Si:ch73-206d17.1. (370 aa)
	AXL	AXL receptor tyrosine kinase. (936 aa)
	egfr	Receptor protein-tyrosine kinase. (1196 aa)
	flt3	Fms-related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1021 aa)
	flt1	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1285 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (683 aa)
	ENSLBEP00000021687	Kinase suppressor of ras 1b. (505 aa)
	YES1	Tyrosine-protein kinase. (534 aa)
	map3k20	Uncharacterized protein. (803 aa)
	LOC109997066	Fibroblast growth factor receptor 4. (945 aa)
	ENSLBEP00000020544	Tyrosine-protein kinase. (514 aa)
	LOC109985019	Tyrosine-protein kinase. (547 aa)
	MAP3K12	Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (944 aa)
	ENSLBEP00000019847	Protein kinase domain-containing protein. (396 aa)
	AMHR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (557 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (790 aa)
	LOC109977228	Protein kinase domain-containing protein. (257 aa)
	LOC109993698	Receptor protein-tyrosine kinase. (1088 aa)
	ENSLBEP00000019299	Receptor tyrosine kinase-like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (863 aa)
	ENSLBEP00000019154	Eph receptor A2 a. (926 aa)
	LOC109978357	Protein kinase domain-containing protein. (450 aa)
	LOC109993733	Serine/threonine/tyrosine kinase 1b. (423 aa)
	LOC109981573	Eph receptor B2a. (1003 aa)
	tie1	Tyrosine kinase with immunoglobulin-like and EGF-like domains 1. (1139 aa)
	itk	Tyrosine-protein kinase. (562 aa)
	lck	Tyrosine-protein kinase. (499 aa)
	ENSLBEP00000017530	Protein kinase domain-containing protein. (100 aa)
	LOC109983824	Uncharacterized protein. (1027 aa)
	LOC109988384	Uncharacterized protein. (452 aa)
	LOC109998157	Uncharacterized protein; Belongs to the protein kinase superfamily. (449 aa)
	nrbp2	Nuclear receptor binding protein 2b. (505 aa)
	ret	Ret proto-oncogene receptor tyrosine kinase. (422 aa)
	LOC109984938	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMHR2	LOC109981135	ENSLBEP00000019710	ENSLBEP00000023544	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.902
AMHR2	LOC109984938	ENSLBEP00000019710	ENSLBEP00000016104	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.917
AMHR2	LOC109989158	ENSLBEP00000019710	ENSLBEP00000026842	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.902
AMHR2	LOC109989354	ENSLBEP00000019710	ENSLBEP00000001646	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.741
AMHR2	LOC109990532	ENSLBEP00000019710	ENSLBEP00000007865	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.913
AMHR2	LOC109992796	ENSLBEP00000019710	ENSLBEP00000038647	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	KIT proto-oncogene, receptor tyrosine kinase b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.405
AMHR2	LOC109993736	ENSLBEP00000019710	ENSLBEP00000025250	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.813
AMHR2	LOC109997179	ENSLBEP00000019710	ENSLBEP00000028262	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.919
AMHR2	acvr2a	ENSLBEP00000019710	ENSLBEP00000006162	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.740
AMHR2	bmpr1a	ENSLBEP00000019710	ENSLBEP00000000624	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...]	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.913
AXL	BRAF	ENSLBEP00000022955	ENSLBEP00000019705	AXL receptor tyrosine kinase.	B-Raf proto-oncogene, serine/threonine kinase.	0.485
AXL	CSK	ENSLBEP00000022955	ENSLBEP00000023504	AXL receptor tyrosine kinase.	Tyrosine-protein kinase.	0.574
AXL	ENSLBEP00000000362	ENSLBEP00000022955	ENSLBEP00000000362	AXL receptor tyrosine kinase.	Tyrosine-protein kinase.	0.623
AXL	ENSLBEP00000000381	ENSLBEP00000022955	ENSLBEP00000000381	AXL receptor tyrosine kinase.	Protein kinase domain-containing protein.	0.623
AXL	ENSLBEP00000004314	ENSLBEP00000022955	ENSLBEP00000004314	AXL receptor tyrosine kinase.	Protein kinase domain-containing protein.	0.651
AXL	ENSLBEP00000004327	ENSLBEP00000022955	ENSLBEP00000004327	AXL receptor tyrosine kinase.	Protein kinase domain-containing protein.	0.651
AXL	ENSLBEP00000012879	ENSLBEP00000022955	ENSLBEP00000012879	AXL receptor tyrosine kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.578
AXL	ENSLBEP00000021687	ENSLBEP00000022955	ENSLBEP00000021687	AXL receptor tyrosine kinase.	Kinase suppressor of ras 1b.	0.485
AXL	LOC109981196	ENSLBEP00000022955	ENSLBEP00000031920	AXL receptor tyrosine kinase.	Tyrosine-protein kinase.	0.651
AXL	LOC109982423	ENSLBEP00000022955	ENSLBEP00000003105	AXL receptor tyrosine kinase.	Tyrosine-protein kinase.	0.578