(35 nodes) AAA ATPase, AAA+ lid domain network (Labrus bergylta)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	katnal2	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (516 aa)
	psmc5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
	LOC109997788	YME1-like 1b; Belongs to the AAA ATPase family. (698 aa)
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (438 aa)
	LOC110000677	Zgc:136908; Belongs to the AAA ATPase family. (802 aa)
	SPAST	Spastin; Belongs to the AAA ATPase family. (462 aa)
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	nvl	Nuclear VCP like. (897 aa)
	SPATA5	Spermatogenesis associated 5. (811 aa)
	katna1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (488 aa)
	LOC109992394	N-ethylmaleimide-sensitive factor b. (746 aa)
	LOC110004984	Uncharacterized protein; Belongs to the AAA ATPase family. (611 aa)
	LOC109982539	Uncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
	yme1l1	YME1-like 1a. (721 aa)
	NSF	N-ethylmaleimide-sensitive factor a. (750 aa)
	LOC109983741	AAA domain-containing protein. (789 aa)
	LOC109982063	ATPase family AAA domain containing 1a; Belongs to the AAA ATPase family. (383 aa)
	atad2	ATPase family AAA domain containing 2. (1497 aa)
	atad1	ATPase family AAA domain containing 1b; Belongs to the AAA ATPase family. (364 aa)
	vps4a	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (436 aa)
	psmc1	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
	LOC109984823	Si:ch1073-174d20.2. (705 aa)
	spata5l1	Spermatogenesis associated 5-like 1. (747 aa)
	spg7	SPG7 matrix AAA peptidase subunit, paraplegin. (723 aa)
	psmc3	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
	ENSLBEP00000002046	Uncharacterized protein. (582 aa)
	pex1	Peroxisomal biogenesis factor 1. (1250 aa)
	psmc4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (404 aa)
	atad2b	ATPase family AAA domain containing 2B. (1290 aa)
	LOC109997926	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (496 aa)
	LOC109995669	Bromo domain-containing protein. (1225 aa)
	psmc2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
	fignl1	Fidgetin-like 1; Belongs to the AAA ATPase family. (647 aa)
	psmc6	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
	LOC110000785	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (553 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000002046	LOC109982539	ENSLBEP00000002046	ENSLBEP00000013880	Uncharacterized protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.452
ENSLBEP00000002046	LOC109995669	ENSLBEP00000002046	ENSLBEP00000035271	Uncharacterized protein.	Bromo domain-containing protein.	0.634
ENSLBEP00000002046	LOC109997926	ENSLBEP00000002046	ENSLBEP00000034261	Uncharacterized protein.	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	0.526
ENSLBEP00000002046	VPS4B	ENSLBEP00000002046	ENSLBEP00000024832	Uncharacterized protein.	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.	0.447
ENSLBEP00000002046	atad2	ENSLBEP00000002046	ENSLBEP00000007680	Uncharacterized protein.	ATPase family AAA domain containing 2.	0.634
ENSLBEP00000002046	atad2b	ENSLBEP00000002046	ENSLBEP00000032586	Uncharacterized protein.	ATPase family AAA domain containing 2B.	0.634
ENSLBEP00000002046	katna1	ENSLBEP00000002046	ENSLBEP00000015826	Uncharacterized protein.	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	0.538
ENSLBEP00000002046	katnal2	ENSLBEP00000002046	ENSLBEP00000028274	Uncharacterized protein.	Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.	0.544
ENSLBEP00000002046	nvl	ENSLBEP00000002046	ENSLBEP00000019302	Uncharacterized protein.	Nuclear VCP like.	0.648
ENSLBEP00000002046	psmc1	ENSLBEP00000002046	ENSLBEP00000007152	Uncharacterized protein.	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	0.850
ENSLBEP00000002046	psmc2	ENSLBEP00000002046	ENSLBEP00000035690	Uncharacterized protein.	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	0.749
ENSLBEP00000002046	psmc3	ENSLBEP00000002046	ENSLBEP00000003894	Uncharacterized protein.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.807
ENSLBEP00000002046	psmc4	ENSLBEP00000002046	ENSLBEP00000032143	Uncharacterized protein.	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family.	0.718
ENSLBEP00000002046	psmc5	ENSLBEP00000002046	ENSLBEP00000026848	Uncharacterized protein.	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.	0.796
ENSLBEP00000002046	psmc6	ENSLBEP00000002046	ENSLBEP00000028956	Uncharacterized protein.	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.760
ENSLBEP00000002046	vps4a	ENSLBEP00000002046	ENSLBEP00000007253	Uncharacterized protein.	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family.	0.447
LOC109982063	LOC109982539	ENSLBEP00000010225	ENSLBEP00000013880	ATPase family AAA domain containing 1a; Belongs to the AAA ATPase family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.440
LOC109982063	LOC109995669	ENSLBEP00000010225	ENSLBEP00000035271	ATPase family AAA domain containing 1a; Belongs to the AAA ATPase family.	Bromo domain-containing protein.	0.454
LOC109982063	LOC109997926	ENSLBEP00000010225	ENSLBEP00000034261	ATPase family AAA domain containing 1a; Belongs to the AAA ATPase family.	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	0.506
LOC109982063	VPS4B	ENSLBEP00000010225	ENSLBEP00000024832	ATPase family AAA domain containing 1a; Belongs to the AAA ATPase family.	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.	0.439