(10 nodes) MAPK1 (ERK2) activation network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109991634	Tyrosine-protein kinase. (1116 aa)
	ENSLBEP00000004299	FERM domain-containing protein. (124 aa)
	ENSLBEP00000004327	Protein kinase domain-containing protein. (192 aa)
	ENSLBEP00000004314	Protein kinase domain-containing protein. (82 aa)
	LOC109981196	Tyrosine-protein kinase. (1130 aa)
	ENSLBEP00000031393	Fibronectin type-III domain-containing protein. (294 aa)
	LOC114921168	Uncharacterized protein. (191 aa)
	LOC109980451	Fibronectin type-III domain-containing protein. (694 aa)
	il6r	Interleukin 6 receptor. (592 aa)
	jak1	Tyrosine-protein kinase. (1307 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000004299	ENSLBEP00000031393	ENSLBEP00000004299	ENSLBEP00000031393	FERM domain-containing protein.	Fibronectin type-III domain-containing protein.	0.679
ENSLBEP00000004299	LOC109980451	ENSLBEP00000004299	ENSLBEP00000018709	FERM domain-containing protein.	Fibronectin type-III domain-containing protein.	0.679
ENSLBEP00000004299	il6r	ENSLBEP00000004299	ENSLBEP00000007297	FERM domain-containing protein.	Interleukin 6 receptor.	0.755
ENSLBEP00000004314	ENSLBEP00000031393	ENSLBEP00000004314	ENSLBEP00000031393	Protein kinase domain-containing protein.	Fibronectin type-III domain-containing protein.	0.679
ENSLBEP00000004314	LOC109980451	ENSLBEP00000004314	ENSLBEP00000018709	Protein kinase domain-containing protein.	Fibronectin type-III domain-containing protein.	0.679
ENSLBEP00000004314	il6r	ENSLBEP00000004314	ENSLBEP00000007297	Protein kinase domain-containing protein.	Interleukin 6 receptor.	0.755
ENSLBEP00000004327	ENSLBEP00000031393	ENSLBEP00000004327	ENSLBEP00000031393	Protein kinase domain-containing protein.	Fibronectin type-III domain-containing protein.	0.679
ENSLBEP00000004327	LOC109980451	ENSLBEP00000004327	ENSLBEP00000018709	Protein kinase domain-containing protein.	Fibronectin type-III domain-containing protein.	0.679
ENSLBEP00000004327	il6r	ENSLBEP00000004327	ENSLBEP00000007297	Protein kinase domain-containing protein.	Interleukin 6 receptor.	0.755
ENSLBEP00000004327	jak1	ENSLBEP00000004327	ENSLBEP00000008428	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.980
ENSLBEP00000031393	ENSLBEP00000004299	ENSLBEP00000031393	ENSLBEP00000004299	Fibronectin type-III domain-containing protein.	FERM domain-containing protein.	0.679
ENSLBEP00000031393	ENSLBEP00000004314	ENSLBEP00000031393	ENSLBEP00000004314	Fibronectin type-III domain-containing protein.	Protein kinase domain-containing protein.	0.679
ENSLBEP00000031393	ENSLBEP00000004327	ENSLBEP00000031393	ENSLBEP00000004327	Fibronectin type-III domain-containing protein.	Protein kinase domain-containing protein.	0.679
ENSLBEP00000031393	LOC109981196	ENSLBEP00000031393	ENSLBEP00000031920	Fibronectin type-III domain-containing protein.	Tyrosine-protein kinase.	0.679
ENSLBEP00000031393	LOC109991634	ENSLBEP00000031393	ENSLBEP00000034325	Fibronectin type-III domain-containing protein.	Tyrosine-protein kinase.	0.679
ENSLBEP00000031393	il6r	ENSLBEP00000031393	ENSLBEP00000007297	Fibronectin type-III domain-containing protein.	Interleukin 6 receptor.	0.929
ENSLBEP00000031393	jak1	ENSLBEP00000031393	ENSLBEP00000008428	Fibronectin type-III domain-containing protein.	Tyrosine-protein kinase.	0.767
LOC109980451	ENSLBEP00000004299	ENSLBEP00000018709	ENSLBEP00000004299	Fibronectin type-III domain-containing protein.	FERM domain-containing protein.	0.679
LOC109980451	ENSLBEP00000004314	ENSLBEP00000018709	ENSLBEP00000004314	Fibronectin type-III domain-containing protein.	Protein kinase domain-containing protein.	0.679
LOC109980451	ENSLBEP00000004327	ENSLBEP00000018709	ENSLBEP00000004327	Fibronectin type-III domain-containing protein.	Protein kinase domain-containing protein.	0.679