STRINGSTRING
ENSLBEP00000012144 ENSLBEP00000012144 LOC110002204 LOC110002204 LOC109984063 LOC109984063 furin furin LOC109990602 LOC109990602 ENSLBEP00000002303 ENSLBEP00000002303 LOC109995950 LOC109995950 hras hras LOC109998547 LOC109998547 LOC110000387 LOC110000387 ntrk1 ntrk1 bdnf bdnf SGK1 SGK1 dusp6 dusp6 LOC109991032 LOC109991032 ap2a1 ap2a1 mapk15 mapk15 SRC SRC ppp4r1 ppp4r1 LOC109982474 LOC109982474 fnbp4 fnbp4 id3 id3 LOC109990528 LOC109990528 LOC109993517 LOC109993517 ENSLBEP00000006245 ENSLBEP00000006245 LOC109998014 LOC109998014 egr1 egr1 egr3 egr3 plcg1 plcg1 relch relch fosl1 fosl1 LOC109980953 LOC109980953 LOC109977551 LOC109977551 ENSLBEP00000009978 ENSLBEP00000009978 LOC110006097 LOC110006097 ENSLBEP00000010350 ENSLBEP00000010350 clta clta LOC109988911 LOC109988911 LOC109984909 LOC109984909 LOC109997530 LOC109997530 ENSLBEP00000011562 ENSLBEP00000011562 ENSLBEP00000011847 ENSLBEP00000011847 ENSLBEP00000027770 ENSLBEP00000027770 LOC109987376 LOC109987376 fndc3b fndc3b LOC109976595 LOC109976595 ENSLBEP00000028365 ENSLBEP00000028365 ENSLBEP00000028622 ENSLBEP00000028622 ENSLBEP00000028630 ENSLBEP00000028630 nab2 nab2 LOC110000232 LOC110000232 crk crk LOC110003306 LOC110003306 bax bax LOC109998395 LOC109998395 LOC109996231 LOC109996231 LOC109975720 LOC109975720 rapgef1 rapgef1 LOC109987449 LOC109987449 ntf3 ntf3 LOC109987681 LOC109987681 vrk3 vrk3 ppp4r4 ppp4r4 LOC109998954 LOC109998954 LOC109998393 LOC109998393 LOC109981803 LOC109981803 LOC110002760 LOC110002760 ap2s1 ap2s1 ppp2cb ppp2cb LOC110002814 LOC110002814 ppp2ca ppp2ca mapk11 mapk11 LOC109993356 LOC109993356 JUND JUND LOC109988720 LOC109988720 kras kras LOC109987579 LOC109987579 LOC109979698 LOC109979698 LOC109975716 LOC109975716 LOC109981499 LOC109981499 LOC109980997 LOC109980997 SRF SRF crkl crkl nab1 nab1 LOC109984231 LOC109984231 pik3cb pik3cb LOC109983747 LOC109983747 dnal4 dnal4 dusp3 dusp3 dock3 dock3 LOC109989568 LOC109989568 fyn fyn srf srf LOC109985531 LOC109985531 CHD4 CHD4 MAPKAPK2 MAPKAPK2 LOC109994747 LOC109994747 ENSLBEP00000016760 ENSLBEP00000016760 ENSLBEP00000016801 ENSLBEP00000016801 ENSLBEP00000016845 ENSLBEP00000016845 ap2m1 ap2m1 FRS2 FRS2 kidins220 kidins220 CREB1 CREB1 LOC109999440 LOC109999440 id2 id2 LOC109975086 LOC109975086 LOC109996569 LOC109996569 LOC109991973 LOC109991973 CSDE1 CSDE1 LOC110003767 LOC110003767 LOC109994795 LOC109994795 map2k1 map2k1 LOC109991982 LOC109991982 LOC109983920 LOC109983920 sh3gl2 sh3gl2 LOC109986219 LOC109986219 LOC109989116 LOC109989116 LOC109977293 LOC109977293 ENSLBEP00000021967 ENSLBEP00000021967 MAPKAPK3 MAPKAPK3 mapk1 mapk1 LOC109982751 LOC109982751 ENSLBEP00000023929 ENSLBEP00000023929 LOC109990780 LOC109990780 LOC110003847 LOC110003847 map2k5 map2k5 LOC109992527 LOC109992527 LOC109999342 LOC109999342 ENSLBEP00000025917 ENSLBEP00000025917 LOC109997143 LOC109997143 creb1 creb1 LOC109994386 LOC109994386
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSLBEP00000012144Uncharacterized protein. (547 aa)
LOC110002204Tyrosine-protein kinase receptor. (798 aa)
LOC109984063Mitogen-activated protein kinase kinase 2b. (394 aa)
furinFurin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (839 aa)
LOC109990602Achaete-scute family bHLH transcription factor 1b. (204 aa)
ENSLBEP00000002303Tyrosine-protein kinase receptor. (588 aa)
LOC109995950Ribosomal protein S6 kinase. (753 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC109998547Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC110000387JunB proto-oncogene, AP-1 transcription factor subunit b. (327 aa)
ntrk1Tyrosine-protein kinase receptor. (801 aa)
bdnfBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (278 aa)
SGK1Serum/glucocorticoid regulated kinase 1. (647 aa)
dusp6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (383 aa)
LOC109991032Ribosomal protein S6 kinase. (792 aa)
ap2a1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (936 aa)
mapk15Mitogen-activated protein kinase. (607 aa)
SRCTyrosine-protein kinase. (549 aa)
ppp4r1WRNPLPNID domain-containing protein. (989 aa)
LOC109982474Tribbles pseudokinase 1. (358 aa)
fnbp4Formin binding protein 4. (858 aa)
id3Inhibitor of DNA binding 3. (122 aa)
LOC109990528Ribosomal protein S6 kinase. (790 aa)
LOC109993517Serine/threonine-protein phosphatase. (309 aa)
ENSLBEP00000006245BZIP domain-containing protein. (78 aa)
LOC109998014NGF domain-containing protein; Belongs to the NGF-beta family. (467 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (510 aa)
egr3Early growth response 3. (410 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1314 aa)
relchRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1190 aa)
fosl1FOS-like antigen 1a. (344 aa)
LOC109980953Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (369 aa)
LOC109977551Ribosomal protein S6 kinase. (811 aa)
ENSLBEP00000009978ETS domain-containing protein. (165 aa)
LOC110006097Fibroblast growth factor receptor substrate 2b. (509 aa)
ENSLBEP00000010350Uncharacterized protein. (71 aa)
cltaClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (227 aa)
LOC109988911AP complex subunit beta. (957 aa)
LOC109984909Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (295 aa)
LOC109997530Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (206 aa)
ENSLBEP00000011562PI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (128 aa)
ENSLBEP00000011847Achaete-scute family bHLH transcription factor 1a. (210 aa)
ENSLBEP00000027770Proprotein convertase subtilisin/kexin type 5b. (489 aa)
LOC109987376V-ral simian leukemia viral oncogene homolog Ba (ras related). (221 aa)
fndc3bFibronectin type III domain containing 3Ba. (933 aa)
LOC109976595Uncharacterized protein. (221 aa)
ENSLBEP00000028365Uncharacterized protein. (78 aa)
ENSLBEP00000028622AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (927 aa)
ENSLBEP00000028630Adaptin_N domain-containing protein. (322 aa)
nab2NGFI-A binding protein 2 (EGR1 binding protein 2). (493 aa)
LOC110000232Tyrosine-protein kinase receptor. (708 aa)
crkCRK proto-oncogene, adaptor protein. (315 aa)
LOC110003306Uncharacterized protein. (310 aa)
baxBCL2 associated X, apoptosis regulator a. (192 aa)
LOC109998395Zgc:55558. (187 aa)
LOC109996231Tyrosine-protein kinase. (439 aa)
LOC109975720Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (814 aa)
rapgef1Rap guanine nucleotide exchange factor (GEF) 1b. (1133 aa)
LOC109987449Inhibitor of DNA binding 4. (141 aa)
ntf3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (318 aa)
LOC109987681Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1167 aa)
vrk3VRK serine/threonine kinase 3. (484 aa)
ppp4r4Protein phosphatase 4, regulatory subunit 4. (652 aa)
LOC109998954Uncharacterized protein. (322 aa)
LOC109998393Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (391 aa)
LOC109981803Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (201 aa)
LOC110002760Uncharacterized protein. (347 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (163 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
LOC110002814Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
mapk11Mitogen-activated protein kinase. (361 aa)
LOC109993356Fibronectin type III domain containing 3A. (1235 aa)
JUNDBZIP domain-containing protein. (292 aa)
LOC109988720Early growth response 2b. (406 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
LOC109987579Tyrosine-protein kinase. (537 aa)
LOC109979698Clat_adaptor_s domain-containing protein. (120 aa)
LOC109975716BZIP domain-containing protein. (311 aa)
LOC109981499Mitogen-activated protein kinase. (364 aa)
LOC109980997MAPK activated protein kinase 2b; Belongs to the protein kinase superfamily. (389 aa)
SRFSerum response factor. (278 aa)
crklV-crk avian sarcoma virus CT10 oncogene homolog-like. (318 aa)
nab1NGFI-A binding protein 1a (EGR1 binding protein 1). (500 aa)
LOC109984231Mitogen-activated protein kinase. (361 aa)
pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1060 aa)
LOC109983747V-ral simian leukemia viral oncogene homolog Aa (ras related). (206 aa)
dnal4Dynein light chain. (106 aa)
dusp3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (200 aa)
dock3Dedicator of cytokinesis 3; Belongs to the DOCK family. (1919 aa)
LOC109989568JunB proto-oncogene, AP-1 transcription factor subunit a. (331 aa)
fynTyrosine-protein kinase. (482 aa)
srfSerum response factor b. (526 aa)
LOC109985531NTPase, KAP family P-loop domain containing 1. (730 aa)
CHD4Uncharacterized protein. (1996 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (384 aa)
LOC109994747Uncharacterized protein. (201 aa)
ENSLBEP00000016760Uncharacterized protein. (107 aa)
ENSLBEP00000016801N-terminal Ras-GEF domain-containing protein. (153 aa)
ENSLBEP00000016845Ras-GEF domain-containing protein. (357 aa)
ap2m1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (442 aa)
FRS2Fibroblast growth factor receptor substrate 2. (488 aa)
kidins220ANK_REP_REGION domain-containing protein. (1702 aa)
CREB1cAMP responsive element binding protein 1. (318 aa)
LOC109999440Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (904 aa)
id2Inhibitor of DNA binding 2a. (161 aa)
LOC109975086Alpha_adaptin_C domain-containing protein. (165 aa)
LOC109996569Insulin receptor substrate 2a. (1029 aa)
LOC109991973JunD proto-oncogene, AP-1 transcription factor subunit. (310 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (869 aa)
LOC110003767KAP NTPase domain-containing protein. (1140 aa)
LOC109994795Mitogen-activated protein kinase. (360 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (352 aa)
LOC109991982Clat_adaptor_s domain-containing protein. (146 aa)
LOC109983920MAPK activated protein kinase 3. (401 aa)
sh3gl2SH3 domain containing GRB2 like 2a, endophilin A1. (368 aa)
LOC109986219Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
LOC109989116Uncharacterized protein. (952 aa)
LOC109977293PID domain-containing protein. (403 aa)
ENSLBEP00000021967SH2 domain-containing protein. (102 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (420 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (371 aa)
LOC109982751Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
ENSLBEP00000023929SH2 domain-containing protein. (80 aa)
LOC109990780SHC adaptor protein 3. (359 aa)
LOC110003847Insulin receptor substrate 2b. (1059 aa)
map2k5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (449 aa)
LOC109992527Activating transcription factor 1. (271 aa)
LOC109999342Protein phosphatase 2, regulatory subunit A, beta b. (685 aa)
ENSLBEP00000025917Tyrosine-protein kinase receptor. (558 aa)
LOC109997143Proprotein convertase subtilisin/kexin type 5a. (1051 aa)
creb1Uncharacterized protein. (329 aa)
LOC109994386BHLH domain-containing protein. (449 aa)
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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