(36 nodes) Regulation of beta-cell development network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hes4	Hairy-related 9. (288 aa)
	hnf1b	HNF1 homeobox Ba. (576 aa)
	onecut2	One cut domain family member. (488 aa)
	nkx6-1	NK6 homeobox 1. (335 aa)
	LOC109999880	One cut domain family member. (447 aa)
	LOC110006056	Insulinoma-associated 1a. (440 aa)
	LOC109996217	Uncharacterized protein. (238 aa)
	hnf1a	HNF1 homeobox a. (555 aa)
	LOC109996929	Uncharacterized protein. (442 aa)
	nkx6-2	NK6 homeobox 2. (303 aa)
	onecut1	One cut domain family member. (378 aa)
	LOC109991952	Hairy-related 8.2. (197 aa)
	RFX4	Regulatory factor X4. (302 aa)
	nkx2-2	NK2 homeobox 2a. (254 aa)
	LOC109992429	Insulinoma-associated 1b. (384 aa)
	LOC109997775	Uncharacterized protein. (411 aa)
	ptf1a	Pancreas associated transcription factor 1a. (273 aa)
	pdx1	Pancreatic and duodenal homeobox 1. (257 aa)
	LOC109987339	Neurogenin 1. (203 aa)
	LOC109982798	One cut domain family member. (459 aa)
	LOC109992084	Non-specific serine/threonine protein kinase. (506 aa)
	LOC109984099	One cut domain family member. (477 aa)
	LOC109988232	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (455 aa)
	pax6	Paired box 6b. (457 aa)
	LOC109975600	Homeobox domain-containing protein. (232 aa)
	LOC109976849	Forkhead box O1 a. (451 aa)
	LOC109993367	Forkhead box O1 a. (678 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (411 aa)
	rfx4	Regulatory factor X, 4. (737 aa)
	hes1	Hairy-related 6. (277 aa)
	LOC109986393	Regulatory factor X, 6. (990 aa)
	ENSLBEP00000031387	Neurogenin 3. (195 aa)
	LOC109975600-2	NK2 homeobox 2b. (258 aa)
	LOC109996204	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (410 aa)
	LOC109993202	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	INSM2	INSM transcriptional repressor 2. (622 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000031387	INSM2	ENSLBEP00000031387	ENSLBEP00000028985	Neurogenin 3.	INSM transcriptional repressor 2.	0.642
ENSLBEP00000031387	LOC109975600	ENSLBEP00000031387	ENSLBEP00000006591	Neurogenin 3.	Homeobox domain-containing protein.	0.602
ENSLBEP00000031387	LOC109975600-2	ENSLBEP00000031387	ENSLBEP00000030891	Neurogenin 3.	NK2 homeobox 2b.	0.602
ENSLBEP00000031387	LOC109982798	ENSLBEP00000031387	ENSLBEP00000023784	Neurogenin 3.	One cut domain family member.	0.411
ENSLBEP00000031387	LOC109986393	ENSLBEP00000031387	ENSLBEP00000032044	Neurogenin 3.	Regulatory factor X, 6.	0.518
ENSLBEP00000031387	LOC109991952	ENSLBEP00000031387	ENSLBEP00000014349	Neurogenin 3.	Hairy-related 8.2.	0.725
ENSLBEP00000031387	LOC109992429	ENSLBEP00000031387	ENSLBEP00000017347	Neurogenin 3.	Insulinoma-associated 1b.	0.642
ENSLBEP00000031387	LOC109996217	ENSLBEP00000031387	ENSLBEP00000010349	Neurogenin 3.	Uncharacterized protein.	0.725
ENSLBEP00000031387	LOC109996929	ENSLBEP00000031387	ENSLBEP00000011478	Neurogenin 3.	Uncharacterized protein.	0.514
ENSLBEP00000031387	LOC109997775	ENSLBEP00000031387	ENSLBEP00000018064	Neurogenin 3.	Uncharacterized protein.	0.514
ENSLBEP00000031387	LOC109999880	ENSLBEP00000031387	ENSLBEP00000007620	Neurogenin 3.	One cut domain family member.	0.455
ENSLBEP00000031387	LOC110006056	ENSLBEP00000031387	ENSLBEP00000008224	Neurogenin 3.	Insulinoma-associated 1a.	0.642
ENSLBEP00000031387	hes1	ENSLBEP00000031387	ENSLBEP00000032754	Neurogenin 3.	Hairy-related 6.	0.854
ENSLBEP00000031387	hes4	ENSLBEP00000031387	ENSLBEP00000027789	Neurogenin 3.	Hairy-related 9.	0.854
ENSLBEP00000031387	nkx2-2	ENSLBEP00000031387	ENSLBEP00000016558	Neurogenin 3.	NK2 homeobox 2a.	0.602
ENSLBEP00000031387	nkx6-1	ENSLBEP00000031387	ENSLBEP00000025191	Neurogenin 3.	NK6 homeobox 1.	0.557
ENSLBEP00000031387	onecut1	ENSLBEP00000031387	ENSLBEP00000012257	Neurogenin 3.	One cut domain family member.	0.641
ENSLBEP00000031387	onecut2	ENSLBEP00000031387	ENSLBEP00000026881	Neurogenin 3.	One cut domain family member.	0.411
ENSLBEP00000031387	pax6	ENSLBEP00000031387	ENSLBEP00000002519	Neurogenin 3.	Paired box 6b.	0.514
ENSLBEP00000031387	pdx1	ENSLBEP00000031387	ENSLBEP00000022752	Neurogenin 3.	Pancreatic and duodenal homeobox 1.	0.522