(27 nodes) Sema3A PAK dependent Axon repulsion network (Labrus bergylta)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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protein homology

Your Input:
	limk2	LIM domain kinase 2. (676 aa)
	LOC109987579	Tyrosine-protein kinase. (537 aa)
	PAK2	Non-specific serine/threonine protein kinase. (510 aa)
	limk1	LIM domain kinase 1a. (670 aa)
	LOC109982928	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2. (736 aa)
	LOC109982952	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (722 aa)
	LOC109997833	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (803 aa)
	LOC109985090	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family. (813 aa)
	ENSLBEP00000026291	Sema domain-containing protein. (398 aa)
	LOC109998839	Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family. (166 aa)
	plxna4	Plexin A4. (1899 aa)
	LOC109993157	Plexin A2. (1841 aa)
	LOC109978465	Serine/threonine-protein kinase PAK 2. (530 aa)
	LOC109998214	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (865 aa)
	fyn	Tyrosine-protein kinase. (482 aa)
	hsp90ab1	Heat shock protein 90, alpha (cytosolic), class B member 1. (725 aa)
	pak2	Non-specific serine/threonine protein kinase. (530 aa)
	pak1	Non-specific serine/threonine protein kinase. (576 aa)
	LOC109981507	Plexin A1a. (1894 aa)
	cfl1	Cofilin 1; Belongs to the actin-binding proteins ADF family. (184 aa)
	PLXNA2	Sema domain-containing protein. (1866 aa)
	LOC109981964	Neuropilin; Belongs to the neuropilin family. (874 aa)
	LOC109997954	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (169 aa)
	PAK3	Non-specific serine/threonine protein kinase. (574 aa)
	LOC109994546	Plexin A1. (1157 aa)
	LOC109993671	Zgc:113162. (331 aa)
	LOC109985229	Uncharacterized protein. (813 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000026291	LOC109978465	ENSLBEP00000026291	ENSLBEP00000021345	Sema domain-containing protein.	Serine/threonine-protein kinase PAK 2.	0.416
ENSLBEP00000026291	LOC109981964	ENSLBEP00000026291	ENSLBEP00000007426	Sema domain-containing protein.	Neuropilin; Belongs to the neuropilin family.	0.892
ENSLBEP00000026291	LOC109982928	ENSLBEP00000026291	ENSLBEP00000031902	Sema domain-containing protein.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.	0.443
ENSLBEP00000026291	LOC109982952	ENSLBEP00000026291	ENSLBEP00000031834	Sema domain-containing protein.	Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.	0.443
ENSLBEP00000026291	LOC109985090	ENSLBEP00000026291	ENSLBEP00000028097	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; Belongs to the semaphorin family.	0.679
ENSLBEP00000026291	LOC109985229	ENSLBEP00000026291	ENSLBEP00000000189	Sema domain-containing protein.	Uncharacterized protein.	0.488
ENSLBEP00000026291	LOC109987579	ENSLBEP00000026291	ENSLBEP00000038378	Sema domain-containing protein.	Tyrosine-protein kinase.	0.574
ENSLBEP00000026291	LOC109993671	ENSLBEP00000026291	ENSLBEP00000000444	Sema domain-containing protein.	Zgc:113162.	0.476
ENSLBEP00000026291	LOC109994546	ENSLBEP00000026291	ENSLBEP00000001061	Sema domain-containing protein.	Plexin A1.	0.926
ENSLBEP00000026291	LOC109997833	ENSLBEP00000026291	ENSLBEP00000029317	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family.	0.679
ENSLBEP00000026291	LOC109998214	ENSLBEP00000026291	ENSLBEP00000019366	Sema domain-containing protein.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	0.679
ENSLBEP00000026291	PAK2	ENSLBEP00000026291	ENSLBEP00000037898	Sema domain-containing protein.	Non-specific serine/threonine protein kinase.	0.416
ENSLBEP00000026291	PAK3	ENSLBEP00000026291	ENSLBEP00000003730	Sema domain-containing protein.	Non-specific serine/threonine protein kinase.	0.452
ENSLBEP00000026291	fyn	ENSLBEP00000026291	ENSLBEP00000014893	Sema domain-containing protein.	Tyrosine-protein kinase.	0.574
ENSLBEP00000026291	hsp90ab1	ENSLBEP00000026291	ENSLBEP00000013706	Sema domain-containing protein.	Heat shock protein 90, alpha (cytosolic), class B member 1.	0.443
ENSLBEP00000026291	limk1	ENSLBEP00000026291	ENSLBEP00000035489	Sema domain-containing protein.	LIM domain kinase 1a.	0.514
ENSLBEP00000026291	limk2	ENSLBEP00000026291	ENSLBEP00000030294	Sema domain-containing protein.	LIM domain kinase 2.	0.514
ENSLBEP00000026291	pak1	ENSLBEP00000026291	ENSLBEP00000012945	Sema domain-containing protein.	Non-specific serine/threonine protein kinase.	0.452
ENSLBEP00000026291	pak2	ENSLBEP00000026291	ENSLBEP00000013620	Sema domain-containing protein.	Non-specific serine/threonine protein kinase.	0.416
LOC109978465	ENSLBEP00000026291	ENSLBEP00000021345	ENSLBEP00000026291	Serine/threonine-protein kinase PAK 2.	Sema domain-containing protein.	0.416