(50 nodes) Unblocking of NMDA receptors, glutamate binding and activation network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSLBEP00000023398	Uncharacterized protein. (831 aa)
	ENSLBEP00000020718	PBPe domain-containing protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (245 aa)
	ENSLBEP00000020342	Protein kinase domain-containing protein. (79 aa)
	ENSLBEP00000019420	ANF_receptor domain-containing protein. (297 aa)
	nefh	IF rod domain-containing protein; Belongs to the intermediate filament family. (756 aa)
	gria2	Glutamate receptor, ionotropic, AMPA 2b. (897 aa)
	ENSLBEP00000018519	CaMKII_AD domain-containing protein. (211 aa)
	dlg3	Discs, large homolog 3 (Drosophila); Belongs to the MAGUK family. (880 aa)
	NEFL	Neurofilament light; Belongs to the intermediate filament family. (629 aa)
	LOC109988253	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1342 aa)
	ENSLBEP00000010218	Protein kinase domain-containing protein. (138 aa)
	LOC109995864	Glutamate receptor, ionotropic, N-methyl D-aspartate 1b. (869 aa)
	ENSLBEP00000010391	CaMKII_AD domain-containing protein. (179 aa)
	ENSLBEP00000010572	IF rod domain-containing protein; Belongs to the intermediate filament family. (174 aa)
	LOC110002890	Uncharacterized protein. (867 aa)
	lrrc7	Leucine rich repeat containing 7. (1382 aa)
	ENSLBEP00000016587	Uncharacterized protein. (82 aa)
	LOC109991316	Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1; Belongs to the protein kinase superfamily. (462 aa)
	LOC109981031	Glutamate receptor, ionotropic, AMPA 1a. (920 aa)
	ENSLBEP00000011424	L27_1 domain-containing protein. (71 aa)
	LOC109982041	Neurofilament, light polypeptide b; Belongs to the intermediate filament family. (651 aa)
	ENSLBEP00000038424	SH3 domain-containing protein. (98 aa)
	ENSLBEP00000038423	PDZ domain-containing protein. (138 aa)
	LOC109997357	Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2. (554 aa)
	LOC109981873	Uncharacterized protein. (1391 aa)
	LOC109993330	Protein kinase domain-containing protein. (614 aa)
	LOC110003520	Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (180 aa)
	LOC109998953	Uncharacterized protein. (905 aa)
	ENSLBEP00000030479	Uncharacterized protein. (234 aa)
	LOC110005370	Uncharacterized protein. (659 aa)
	ENSLBEP00000028554	L27_1 domain-containing protein. (58 aa)
	ENSLBEP00000028543	Uncharacterized protein. (54 aa)
	LOC109993199	Discs, large homolog 2 (Drosophila). (935 aa)
	ENSLBEP00000027101	Uncharacterized protein. (510 aa)
	LOC109985652	Glutamate receptor, ionotropic, N-methyl D-aspartate 1a. (951 aa)
	ENSLBEP00000026089	ANF_receptor domain-containing protein. (320 aa)
	ENSLBEP00000025365	PBPe domain-containing protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (253 aa)
	LOC109993686	Glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b. (1831 aa)
	ina	Internexin neuronal intermediate filament protein, alpha b; Belongs to the intermediate filament family. (513 aa)
	ENSLBEP00000001908	Protein kinase domain-containing protein. (112 aa)
	LOC109983533	Calcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (477 aa)
	grin2a	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a. (1433 aa)
	LOC109989970	Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2. (519 aa)
	LOC109981486	Glutamate receptor, ionotropic, AMPA 3a. (886 aa)
	LOC109983543	Discs, large homolog 4a (Drosophila); Belongs to the MAGUK family. (809 aa)
	LOC109994116	Glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca. (1391 aa)
	LOC109996473	Uncharacterized protein. (882 aa)
	LOC109977533	CaMKII_AD domain-containing protein. (153 aa)
	LOC109997502	IF rod domain-containing protein; Belongs to the intermediate filament family. (456 aa)
	nefm	Neurofilament, medium polypeptide a; Belongs to the intermediate filament family. (910 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000001908	ENSLBEP00000011424	ENSLBEP00000001908	ENSLBEP00000011424	Protein kinase domain-containing protein.	L27_1 domain-containing protein.	0.525
ENSLBEP00000001908	ENSLBEP00000016587	ENSLBEP00000001908	ENSLBEP00000016587	Protein kinase domain-containing protein.	Uncharacterized protein.	0.630
ENSLBEP00000001908	ENSLBEP00000019420	ENSLBEP00000001908	ENSLBEP00000019420	Protein kinase domain-containing protein.	ANF_receptor domain-containing protein.	0.654
ENSLBEP00000001908	ENSLBEP00000020718	ENSLBEP00000001908	ENSLBEP00000020718	Protein kinase domain-containing protein.	PBPe domain-containing protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.667
ENSLBEP00000001908	ENSLBEP00000023398	ENSLBEP00000001908	ENSLBEP00000023398	Protein kinase domain-containing protein.	Uncharacterized protein.	0.667
ENSLBEP00000001908	ENSLBEP00000025365	ENSLBEP00000001908	ENSLBEP00000025365	Protein kinase domain-containing protein.	PBPe domain-containing protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.641
ENSLBEP00000001908	ENSLBEP00000026089	ENSLBEP00000001908	ENSLBEP00000026089	Protein kinase domain-containing protein.	ANF_receptor domain-containing protein.	0.657
ENSLBEP00000001908	ENSLBEP00000027101	ENSLBEP00000001908	ENSLBEP00000027101	Protein kinase domain-containing protein.	Uncharacterized protein.	0.525
ENSLBEP00000001908	ENSLBEP00000028543	ENSLBEP00000001908	ENSLBEP00000028543	Protein kinase domain-containing protein.	Uncharacterized protein.	0.525
ENSLBEP00000001908	ENSLBEP00000028554	ENSLBEP00000001908	ENSLBEP00000028554	Protein kinase domain-containing protein.	L27_1 domain-containing protein.	0.525
ENSLBEP00000001908	ENSLBEP00000030479	ENSLBEP00000001908	ENSLBEP00000030479	Protein kinase domain-containing protein.	Uncharacterized protein.	0.525
ENSLBEP00000001908	ENSLBEP00000038423	ENSLBEP00000001908	ENSLBEP00000038423	Protein kinase domain-containing protein.	PDZ domain-containing protein.	0.525
ENSLBEP00000001908	ENSLBEP00000038424	ENSLBEP00000001908	ENSLBEP00000038424	Protein kinase domain-containing protein.	SH3 domain-containing protein.	0.525
ENSLBEP00000001908	LOC109981031	ENSLBEP00000001908	ENSLBEP00000017674	Protein kinase domain-containing protein.	Glutamate receptor, ionotropic, AMPA 1a.	0.641
ENSLBEP00000001908	LOC109981486	ENSLBEP00000001908	ENSLBEP00000003755	Protein kinase domain-containing protein.	Glutamate receptor, ionotropic, AMPA 3a.	0.641
ENSLBEP00000001908	LOC109981873	ENSLBEP00000001908	ENSLBEP00000036956	Protein kinase domain-containing protein.	Uncharacterized protein.	0.639
ENSLBEP00000001908	LOC109983543	ENSLBEP00000001908	ENSLBEP00000004232	Protein kinase domain-containing protein.	Discs, large homolog 4a (Drosophila); Belongs to the MAGUK family.	0.525
ENSLBEP00000001908	LOC109985652	ENSLBEP00000001908	ENSLBEP00000026124	Protein kinase domain-containing protein.	Glutamate receptor, ionotropic, N-methyl D-aspartate 1a.	0.654
ENSLBEP00000001908	LOC109988253	ENSLBEP00000001908	ENSLBEP00000008940	Protein kinase domain-containing protein.	Glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	0.639
ENSLBEP00000001908	LOC109993199	ENSLBEP00000001908	ENSLBEP00000028288	Protein kinase domain-containing protein.	Discs, large homolog 2 (Drosophila).	0.525