(12 nodes) Signal transduction by L1 network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAK3	Non-specific serine/threonine protein kinase. (574 aa)
	LOC109984063	Mitogen-activated protein kinase kinase 2b. (394 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (371 aa)
	MCMDC2	Minichromosome maintenance domain containing 2. (630 aa)
	map2k1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (352 aa)
	hmcn1	Hemicentin 1. (4930 aa)
	LOC109998393	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (391 aa)
	ENSLBEP00000031482	Uncharacterized protein. (1392 aa)
	pak1	Non-specific serine/threonine protein kinase. (576 aa)
	ENSLBEP00000031378	Uncharacterized protein. (239 aa)
	ENSLBEP00000031329	Uncharacterized protein. (792 aa)
	LOC109982751	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000031329	ENSLBEP00000031378	ENSLBEP00000031329	ENSLBEP00000031378	Uncharacterized protein.	Uncharacterized protein.	0.921
ENSLBEP00000031329	ENSLBEP00000031482	ENSLBEP00000031329	ENSLBEP00000031482	Uncharacterized protein.	Uncharacterized protein.	0.917
ENSLBEP00000031378	ENSLBEP00000031329	ENSLBEP00000031378	ENSLBEP00000031329	Uncharacterized protein.	Uncharacterized protein.	0.921
ENSLBEP00000031378	ENSLBEP00000031482	ENSLBEP00000031378	ENSLBEP00000031482	Uncharacterized protein.	Uncharacterized protein.	0.905
ENSLBEP00000031482	ENSLBEP00000031329	ENSLBEP00000031482	ENSLBEP00000031329	Uncharacterized protein.	Uncharacterized protein.	0.917
ENSLBEP00000031482	ENSLBEP00000031378	ENSLBEP00000031482	ENSLBEP00000031378	Uncharacterized protein.	Uncharacterized protein.	0.905
LOC109982751	LOC109998393	ENSLBEP00000023713	ENSLBEP00000032896	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.919
LOC109982751	PAK3	ENSLBEP00000023713	ENSLBEP00000003730	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.798
LOC109982751	mapk1	ENSLBEP00000023713	ENSLBEP00000023541	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.919
LOC109982751	pak1	ENSLBEP00000023713	ENSLBEP00000012945	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.797
LOC109984063	LOC109998393	ENSLBEP00000001006	ENSLBEP00000032896	Mitogen-activated protein kinase kinase 2b.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.919
LOC109984063	PAK3	ENSLBEP00000001006	ENSLBEP00000003730	Mitogen-activated protein kinase kinase 2b.	Non-specific serine/threonine protein kinase.	0.798
LOC109984063	mapk1	ENSLBEP00000001006	ENSLBEP00000023541	Mitogen-activated protein kinase kinase 2b.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.919
LOC109984063	pak1	ENSLBEP00000001006	ENSLBEP00000012945	Mitogen-activated protein kinase kinase 2b.	Non-specific serine/threonine protein kinase.	0.797
LOC109998393	LOC109982751	ENSLBEP00000032896	ENSLBEP00000023713	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	0.919
LOC109998393	LOC109984063	ENSLBEP00000032896	ENSLBEP00000001006	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase kinase 2b.	0.919
LOC109998393	PAK3	ENSLBEP00000032896	ENSLBEP00000003730	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Non-specific serine/threonine protein kinase.	0.553
LOC109998393	map2k1	ENSLBEP00000032896	ENSLBEP00000020302	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.	0.919
LOC109998393	pak1	ENSLBEP00000032896	ENSLBEP00000012945	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Non-specific serine/threonine protein kinase.	0.553
PAK3	LOC109982751	ENSLBEP00000003730	ENSLBEP00000023713	Non-specific serine/threonine protein kinase.	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.	0.798