(35 nodes) RNA Polymerase I Transcription Termination network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (454 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (162 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (343 aa)
	LOC109996949	Caveolae associated protein 1b. (466 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	ercc3	Excision repair cross-complementation group 3. (782 aa)
	polr2l	Polymerase (RNA) II (DNA directed) polypeptide L. (67 aa)
	ENSLBEP00000001627	Wu:fj64h06. (809 aa)
	tbp	TATA box binding protein. (301 aa)
	polr1e	RNA polymerase I subunit E. (414 aa)
	LOC110003613	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1130 aa)
	polr2k	Polymerase (RNA) II (DNA directed) polypeptide K. (58 aa)
	POLR2E	RNA polymerase II subunit E. (210 aa)
	ENSLBEP00000032598	TATA box binding protein like 2. (727 aa)
	TWISTNB	TWIST neighbor. (378 aa)
	cd3eap	CD3e molecule, epsilon associated protein. (326 aa)
	polr2f	Polymerase (RNA) II (DNA directed) polypeptide F. (118 aa)
	polr1c	RNA polymerase I and III subunit C. (351 aa)
	ubtf	Upstream binding transcription factor. (709 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (324 aa)
	GTF2H5	General transcription factor IIH, polypeptide 5. (71 aa)
	cavin1	Caveolae associated protein 1a. (421 aa)
	LOC109989392	General transcription factor IIH subunit. (418 aa)
	ENSLBEP00000020390	Myb-like domain-containing protein. (514 aa)
	LOC109978489	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (126 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	polr1a	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1604 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (535 aa)
	taf1b	TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B. (585 aa)
	LOC110003092	Uncharacterized protein. (296 aa)
	ENSLBEP00000013103	TATA box binding protein (TBP)-associated factor, RNA polymerase I, A. (394 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	gtf2h5	General transcription factor IIH subunit 5. (71 aa)
	LOC109979124	Helicase ATP-binding domain-containing protein. (628 aa)
	znrd1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (118 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000001627	ENSLBEP00000020390	ENSLBEP00000001627	ENSLBEP00000020390	Wu:fj64h06.	Myb-like domain-containing protein.	0.640
ENSLBEP00000001627	ENSLBEP00000032598	ENSLBEP00000001627	ENSLBEP00000032598	Wu:fj64h06.	TATA box binding protein like 2.	0.768
ENSLBEP00000001627	GTF2H5	ENSLBEP00000001627	ENSLBEP00000007997	Wu:fj64h06.	General transcription factor IIH, polypeptide 5.	0.628
ENSLBEP00000001627	LOC109978489	ENSLBEP00000001627	ENSLBEP00000022447	Wu:fj64h06.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.516
ENSLBEP00000001627	LOC109979124	ENSLBEP00000001627	ENSLBEP00000014717	Wu:fj64h06.	Helicase ATP-binding domain-containing protein.	0.514
ENSLBEP00000001627	LOC110003092	ENSLBEP00000001627	ENSLBEP00000025764	Wu:fj64h06.	Uncharacterized protein.	0.768
ENSLBEP00000001627	LOC110003613	ENSLBEP00000001627	ENSLBEP00000036624	Wu:fj64h06.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.665
ENSLBEP00000001627	POLR2E	ENSLBEP00000001627	ENSLBEP00000032923	Wu:fj64h06.	RNA polymerase II subunit E.	0.635
ENSLBEP00000001627	TWISTNB	ENSLBEP00000001627	ENSLBEP00000032121	Wu:fj64h06.	TWIST neighbor.	0.660
ENSLBEP00000001627	ccnh	ENSLBEP00000001627	ENSLBEP00000008219	Wu:fj64h06.	Cyclin H; Belongs to the cyclin family.	0.664
ENSLBEP00000001627	cd3eap	ENSLBEP00000001627	ENSLBEP00000010628	Wu:fj64h06.	CD3e molecule, epsilon associated protein.	0.589
ENSLBEP00000001627	cdk7	ENSLBEP00000001627	ENSLBEP00000019226	Wu:fj64h06.	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily.	0.603
ENSLBEP00000001627	ercc2	ENSLBEP00000001627	ENSLBEP00000013761	Wu:fj64h06.	Excision repair cross-complementation group 2.	0.514
ENSLBEP00000001627	ercc3	ENSLBEP00000001627	ENSLBEP00000000642	Wu:fj64h06.	Excision repair cross-complementation group 3.	0.670
ENSLBEP00000001627	gtf2h1	ENSLBEP00000001627	ENSLBEP00000024749	Wu:fj64h06.	General transcription factor IIH, polypeptide 1.	0.628
ENSLBEP00000001627	gtf2h5	ENSLBEP00000001627	ENSLBEP00000019603	Wu:fj64h06.	General transcription factor IIH subunit 5.	0.628
ENSLBEP00000001627	mnat1	ENSLBEP00000001627	ENSLBEP00000030654	Wu:fj64h06.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.734
ENSLBEP00000001627	polr1a	ENSLBEP00000001627	ENSLBEP00000020161	Wu:fj64h06.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.694
ENSLBEP00000001627	polr1c	ENSLBEP00000001627	ENSLBEP00000019446	Wu:fj64h06.	RNA polymerase I and III subunit C.	0.628
ENSLBEP00000001627	polr1e	ENSLBEP00000001627	ENSLBEP00000004016	Wu:fj64h06.	RNA polymerase I subunit E.	0.662