(8 nodes) Signal attenuation network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109995271	Preproinsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (121 aa)
	LOC110006110	Insulin-like. (121 aa)
	insr	Tyrosine-protein kinase receptor. (1364 aa)
	LOC109981109	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (109 aa)
	LOC109976595	Uncharacterized protein. (221 aa)
	LOC109990889	Growth factor receptor-bound protein 10a. (592 aa)
	grb10	Growth factor receptor-bound protein 10b. (563 aa)
	LOC109987794	Tyrosine-protein kinase receptor. (1276 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109976595	LOC109981109	ENSLBEP00000028315	ENSLBEP00000018238	Uncharacterized protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.572
LOC109976595	LOC109987794	ENSLBEP00000028315	ENSLBEP00000007125	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.792
LOC109976595	LOC109990889	ENSLBEP00000028315	ENSLBEP00000033082	Uncharacterized protein.	Growth factor receptor-bound protein 10a.	0.666
LOC109976595	LOC109995271	ENSLBEP00000028315	ENSLBEP00000007224	Uncharacterized protein.	Preproinsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.572
LOC109976595	LOC110006110	ENSLBEP00000028315	ENSLBEP00000011075	Uncharacterized protein.	Insulin-like.	0.572
LOC109976595	grb10	ENSLBEP00000028315	ENSLBEP00000037298	Uncharacterized protein.	Growth factor receptor-bound protein 10b.	0.666
LOC109976595	insr	ENSLBEP00000028315	ENSLBEP00000008641	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.792
LOC109981109	LOC109976595	ENSLBEP00000018238	ENSLBEP00000028315	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.572
LOC109981109	LOC109987794	ENSLBEP00000018238	ENSLBEP00000007125	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.950
LOC109981109	LOC109990889	ENSLBEP00000018238	ENSLBEP00000033082	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Growth factor receptor-bound protein 10a.	0.557
LOC109981109	LOC109995271	ENSLBEP00000018238	ENSLBEP00000007224	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Preproinsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.725
LOC109981109	LOC110006110	ENSLBEP00000018238	ENSLBEP00000011075	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin-like.	0.725
LOC109981109	grb10	ENSLBEP00000018238	ENSLBEP00000037298	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Growth factor receptor-bound protein 10b.	0.557
LOC109981109	insr	ENSLBEP00000018238	ENSLBEP00000008641	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.950
LOC109987794	LOC109976595	ENSLBEP00000007125	ENSLBEP00000028315	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.792
LOC109987794	LOC109981109	ENSLBEP00000007125	ENSLBEP00000018238	Tyrosine-protein kinase receptor.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.950
LOC109987794	LOC109990889	ENSLBEP00000007125	ENSLBEP00000033082	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 10a.	0.934
LOC109987794	LOC109995271	ENSLBEP00000007125	ENSLBEP00000007224	Tyrosine-protein kinase receptor.	Preproinsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.889
LOC109987794	LOC110006110	ENSLBEP00000007125	ENSLBEP00000011075	Tyrosine-protein kinase receptor.	Insulin-like.	0.889
LOC109987794	grb10	ENSLBEP00000007125	ENSLBEP00000037298	Tyrosine-protein kinase receptor.	Growth factor receptor-bound protein 10b.	0.934