(42 nodes) Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109987693	Si:dkey-71h2.2. (284 aa)
	LOC110002623	Amyloid beta (A4) precursor protein-binding, family A, member 2a. (892 aa)
	ENSLBEP00000019516	PID domain-containing protein. (359 aa)
	LOC109989957	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1. (1265 aa)
	apbb1	Amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65). (684 aa)
	rabgap1	RAB GTPase activating protein 1. (1092 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (457 aa)
	LOC110001417	Amyloid beta precursor protein binding family A member 3. (721 aa)
	ENSLBEP00000001394	PID domain-containing protein. (234 aa)
	LOC109982996	Amyloid beta (A4) precursor protein-binding, family A, member 2b. (996 aa)
	mapk8ip2	Mitogen-activated protein kinase 8 interacting protein 2. (1218 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (313 aa)
	ENSLBEP00000018544	Tensin 1. (1111 aa)
	LOC109997059	DAB adaptor protein 1b. (580 aa)
	LOC109991919	NUMB like endocytic adaptor protein. (753 aa)
	APBA1	Amyloid beta precursor protein binding family A member 1. (936 aa)
	LOC109995368	Nitric oxide synthase 1 (neuronal) adaptor protein b. (519 aa)
	ANKS1A	Ankyrin repeat and sterile alpha motif domain containing 1A. (1089 aa)
	dab1	DAB adaptor protein 1a. (568 aa)
	LOC109996927	Uncharacterized protein. (322 aa)
	LOC110001050	Epidermal growth factor receptor pathway substrate 8a. (801 aa)
	gulp1	GULP PTB domain containing engulfment adaptor 1a. (413 aa)
	ENSLBEP00000002878	Amyloid beta (A4) precursor protein-binding, family B, member 3. (336 aa)
	LOC109986049	Tensin 1b. (1768 aa)
	tbc1d4	TBC1 domain family, member 4. (1250 aa)
	TNS3-2	Tensin 3. (1236 aa)
	LOC109984439	Si:dkey-34e4.1. (657 aa)
	LOC109981729	Ankyrin repeat and sterile alpha motif domain containing 1Ab. (497 aa)
	numb	NUMB endocytic adaptor protein. (666 aa)
	ENSLBEP00000027191	Uncharacterized protein. (564 aa)
	MAPK8IP1	Mitogen-activated protein kinase 8 interacting protein 1. (803 aa)
	LOC109985111	PID domain-containing protein. (175 aa)
	LOC109985082	Tensin 2a. (1720 aa)
	shc2	SHC (Src homology 2 domain containing) transforming protein 2. (532 aa)
	fam43b	Family with sequence similarity 43 member B. (325 aa)
	LOC109990780	SHC adaptor protein 3. (359 aa)
	LOC109985669	Amyloid beta (A4) precursor protein-binding, family A, member 1b. (1138 aa)
	TNS3	Tensin 3. (1386 aa)
	LOC109977293	PID domain-containing protein. (403 aa)
	dab2	DAB adaptor protein 2. (764 aa)
	EPS8	Epidermal growth factor receptor pathway substrate 8. (809 aa)
	ENSLBEP00000020771	PID domain-containing protein. (284 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000019516	LOC109984439	ENSLBEP00000019516	ENSLBEP00000032959	PID domain-containing protein.	Si:dkey-34e4.1.	0.851
ENSLBEP00000019516	LOC109995368	ENSLBEP00000019516	ENSLBEP00000012778	PID domain-containing protein.	Nitric oxide synthase 1 (neuronal) adaptor protein b.	0.853
LOC109977293	shc1	ENSLBEP00000021938	ENSLBEP00000006767	PID domain-containing protein.	SHC (Src homology 2 domain containing) transforming protein 1.	0.836
LOC109977293	shc2	ENSLBEP00000021938	ENSLBEP00000025124	PID domain-containing protein.	SHC (Src homology 2 domain containing) transforming protein 2.	0.829
LOC109984439	ENSLBEP00000019516	ENSLBEP00000032959	ENSLBEP00000019516	Si:dkey-34e4.1.	PID domain-containing protein.	0.851
LOC109984439	LOC109995368	ENSLBEP00000032959	ENSLBEP00000012778	Si:dkey-34e4.1.	Nitric oxide synthase 1 (neuronal) adaptor protein b.	0.853
LOC109985111	LOC109997059	ENSLBEP00000025459	ENSLBEP00000015805	PID domain-containing protein.	DAB adaptor protein 1b.	0.477
LOC109985111	dab1	ENSLBEP00000025459	ENSLBEP00000012540	PID domain-containing protein.	DAB adaptor protein 1a.	0.477
LOC109985111	dab2	ENSLBEP00000025459	ENSLBEP00000021878	PID domain-containing protein.	DAB adaptor protein 2.	0.477
LOC109987693	LOC109997059	ENSLBEP00000002424	ENSLBEP00000015805	Si:dkey-71h2.2.	DAB adaptor protein 1b.	0.477
LOC109987693	dab1	ENSLBEP00000002424	ENSLBEP00000012540	Si:dkey-71h2.2.	DAB adaptor protein 1a.	0.477
LOC109987693	dab2	ENSLBEP00000002424	ENSLBEP00000021878	Si:dkey-71h2.2.	DAB adaptor protein 2.	0.839
LOC109987693	ldlrap1	ENSLBEP00000002424	ENSLBEP00000019092	Si:dkey-71h2.2.	Low density lipoprotein receptor adaptor protein 1b.	0.841
LOC109990780	shc1	ENSLBEP00000023992	ENSLBEP00000006767	SHC adaptor protein 3.	SHC (Src homology 2 domain containing) transforming protein 1.	0.834
LOC109990780	shc2	ENSLBEP00000023992	ENSLBEP00000025124	SHC adaptor protein 3.	SHC (Src homology 2 domain containing) transforming protein 2.	0.827
LOC109991919	numb	ENSLBEP00000015096	ENSLBEP00000030242	NUMB like endocytic adaptor protein.	NUMB endocytic adaptor protein.	0.845
LOC109995368	ENSLBEP00000019516	ENSLBEP00000012778	ENSLBEP00000019516	Nitric oxide synthase 1 (neuronal) adaptor protein b.	PID domain-containing protein.	0.853
LOC109995368	LOC109984439	ENSLBEP00000012778	ENSLBEP00000032959	Nitric oxide synthase 1 (neuronal) adaptor protein b.	Si:dkey-34e4.1.	0.853
LOC109996927	MAPK8IP1	ENSLBEP00000010489	ENSLBEP00000025837	Uncharacterized protein.	Mitogen-activated protein kinase 8 interacting protein 1.	0.841
LOC109997059	LOC109985111	ENSLBEP00000015805	ENSLBEP00000025459	DAB adaptor protein 1b.	PID domain-containing protein.	0.477