(81 nodes) Alanine, aspartate and glutamate metabolism network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109993508	Glutamine-fructose-6-phosphate transaminase 2. (685 aa)
	ENSLBEP00000037773	EF-hand_14 domain-containing protein. (539 aa)
	LOC109989845	N-acetylated alpha-linked acidic dipeptidase 2. (800 aa)
	asnsd1	Asparagine synthetase domain containing 1. (612 aa)
	asns	Asparagine synthetase [glutamine-hydrolyzing]. (561 aa)
	LOC109982084	Serine--pyruvate aminotransferase. (391 aa)
	LOC109993316	Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (542 aa)
	ENSLBEP00000034868	N-acetyltransferase domain-containing protein. (278 aa)
	LOC109981280	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)
	LOC110000038	Aminotran_1_2 domain-containing protein. (475 aa)
	ACY3	Aminoacylase 3. (333 aa)
	asrgl1	Asparaginase like 1. (310 aa)
	LOC110001316	Aspartoacylase (aminocyclase) 3, tandem duplicate 2. (309 aa)
	nit2	Nitrilase family, member 2. (286 aa)
	got1	Aspartate aminotransferase. (427 aa)
	got2	Aspartate aminotransferase. (428 aa)
	LOC109982869	Ribosomal modification protein rimK-like family member A. (401 aa)
	aspa	Aspartoacylase. (313 aa)
	LOC109990831	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (473 aa)
	taf1b	TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B. (585 aa)
	slc22a16	Solute carrier family 22 member 16. (572 aa)
	ppat	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (504 aa)
	LOC109985642	Glutamine synthetase. (374 aa)
	LOC109991436	Glutamine synthetase. (371 aa)
	LOC109991423	Serine--pyruvate aminotransferase. (429 aa)
	ENSLBEP00000024898	Uncharacterized protein. (115 aa)
	gpr143	G protein-coupled receptor 143. (464 aa)
	LOC110003066	Uncharacterized protein. (229 aa)
	LOC109990800	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (482 aa)
	ASS1	Argininosuccinate synthase 1. (401 aa)
	LOC109990792	Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (485 aa)
	gad1	Glutamate decarboxylase 1a. (592 aa)
	LOC109989610	Amine oxidase. (557 aa)
	aldh4a1	Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (530 aa)
	LOC109984998	Glutamic pyruvate transaminase (alanine aminotransferase) 2, like. (574 aa)
	cad	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. (2128 aa)
	LOC109985917	Aminotran_1_2 domain-containing protein. (477 aa)
	GPT	Glutamic--pyruvic transaminase. (491 aa)
	LOC110005900	Glutaminase kidney isoform, mitochondrial-like. (90 aa)
	naaladl1	Si:ch211-214j8.1. (744 aa)
	LOC109978353	Aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase). (182 aa)
	GOT1	Aspartate aminotransferase. (420 aa)
	gpkow	G patch domain and KOW motifs. (516 aa)
	LOC109983207	Si:dkey-103j14.5. (310 aa)
	LOC109998161	Si:dkey-30c15.2. (351 aa)
	adsl	Adenylosuccinate lyase. (407 aa)
	LOC109985312	Glutaminase 2a (liver, mitochondrial). (608 aa)
	ENSLBEP00000013755	Si:ch211-256m1.8. (1583 aa)
	LOC109994750	Glutaminase a. (624 aa)
	gad2	Glutamate decarboxylase 2. (585 aa)
	ENSLBEP00000012694	Uncharacterized protein. (218 aa)
	LOC109982063	ATPase family AAA domain containing 1a; Belongs to the AAA ATPase family. (383 aa)
	LOC109999303	Uncharacterized protein. (298 aa)
	LOC109994678	Zgc:110319. (262 aa)
	ENSLBEP00000008971	Uncharacterized protein. (316 aa)
	ENSLBEP00000008344	Glutamine amidotransferase type-1 domain-containing protein. (270 aa)
	atad1	ATPase family AAA domain containing 1b; Belongs to the AAA ATPase family. (364 aa)
	LOC109995580	Glutamate decarboxylase 1b. (583 aa)
	LOC110005628	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (436 aa)
	ddo	Zgc:172341. (331 aa)
	LOC109980856	Glutaminase 2b (liver, mitochondrial). (599 aa)
	LOC110001974	Glutamine--fructose-6-phosphate transaminase 1. (682 aa)
	LOC109986547	Aminotran_1_2 domain-containing protein. (486 aa)
	LOC110001870	NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae). (255 aa)
	LOC110001533	Glutamic-oxaloacetic transaminase 1 like 1. (439 aa)
	LOC109995202	Glutaminase like. (539 aa)
	ENSLBEP00000004908	Uncharacterized protein. (867 aa)
	abat	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
	il4i1	Amine oxidase. (511 aa)
	LOC109991037	Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (557 aa)
	cps1	Carbamoyl-phosphate synthase 1, mitochondrial. (1506 aa)
	NAALADL2	N-acetylated alpha-linked acidic dipeptidase like 2. (691 aa)
	LOC110004240	FH2 domain-containing protein. (332 aa)
	LOC109982133	Glutamate-ammonia ligase (glutamine synthase) b; Belongs to the glutamine synthetase family. (341 aa)
	LOC109982142	Glutamine synthetase. (373 aa)
	asl	Argininosuccinate lyase. (465 aa)
	lgsn	Lengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (685 aa)
	LOC110000348	Taspase, threonine aspartase, 1. (370 aa)
	nat8l	N-acetyltransferase 8-like. (278 aa)
	ENSLBEP00000000315	ANK_REP_REGION domain-containing protein. (98 aa)
	LOC109976461	ELFV_dehydrog domain-containing protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (546 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACY3	ASS1	ENSLBEP00000034223	ENSLBEP00000023413	Aminoacylase 3.	Argininosuccinate synthase 1.	0.827
ACY3	ENSLBEP00000004908	ENSLBEP00000034223	ENSLBEP00000004908	Aminoacylase 3.	Uncharacterized protein.	0.668
ACY3	ENSLBEP00000008344	ENSLBEP00000034223	ENSLBEP00000008344	Aminoacylase 3.	Glutamine amidotransferase type-1 domain-containing protein.	0.640
ACY3	ENSLBEP00000008971	ENSLBEP00000034223	ENSLBEP00000008971	Aminoacylase 3.	Uncharacterized protein.	0.627
ACY3	ENSLBEP00000013755	ENSLBEP00000034223	ENSLBEP00000013755	Aminoacylase 3.	Si:ch211-256m1.8.	0.824
ACY3	ENSLBEP00000034868	ENSLBEP00000034223	ENSLBEP00000034868	Aminoacylase 3.	N-acetyltransferase domain-containing protein.	0.792
ACY3	LOC109983207	ENSLBEP00000034223	ENSLBEP00000016920	Aminoacylase 3.	Si:dkey-103j14.5.	0.627
ACY3	LOC109989610	ENSLBEP00000034223	ENSLBEP00000022762	Aminoacylase 3.	Amine oxidase.	0.736
ACY3	LOC109989845	ENSLBEP00000034223	ENSLBEP00000037523	Aminoacylase 3.	N-acetylated alpha-linked acidic dipeptidase 2.	0.726
ACY3	LOC109995580	ENSLBEP00000034223	ENSLBEP00000006516	Aminoacylase 3.	Glutamate decarboxylase 1b.	0.712
ACY3	LOC109998161	ENSLBEP00000034223	ENSLBEP00000015458	Aminoacylase 3.	Si:dkey-30c15.2.	0.489
ACY3	LOC109999303	ENSLBEP00000034223	ENSLBEP00000009322	Aminoacylase 3.	Uncharacterized protein.	0.627
ACY3	LOC110004240	ENSLBEP00000034223	ENSLBEP00000001101	Aminoacylase 3.	FH2 domain-containing protein.	0.720
ACY3	NAALADL2	ENSLBEP00000034223	ENSLBEP00000001994	Aminoacylase 3.	N-acetylated alpha-linked acidic dipeptidase like 2.	0.667
ACY3	asns	ENSLBEP00000034223	ENSLBEP00000037271	Aminoacylase 3.	Asparagine synthetase [glutamine-hydrolyzing].	0.825
ACY3	asrgl1	ENSLBEP00000034223	ENSLBEP00000032812	Aminoacylase 3.	Asparaginase like 1.	0.627
ACY3	cad	ENSLBEP00000034223	ENSLBEP00000021889	Aminoacylase 3.	Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase.	0.668
ACY3	cps1	ENSLBEP00000034223	ENSLBEP00000003003	Aminoacylase 3.	Carbamoyl-phosphate synthase 1, mitochondrial.	0.668
ACY3	gad1	ENSLBEP00000034223	ENSLBEP00000023206	Aminoacylase 3.	Glutamate decarboxylase 1a.	0.712
ACY3	gad2	ENSLBEP00000034223	ENSLBEP00000012992	Aminoacylase 3.	Glutamate decarboxylase 2.	0.826