(48 nodes) Glycosaminoglycan degradation network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109995359	Beta-galactosidase. (648 aa)
	rabggtb	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (370 aa)
	get4	Guided entry of tail-anchored proteins factor 4. (323 aa)
	LOC109985242	Uncharacterized protein. (416 aa)
	LOC109989887	Sulfatase domain-containing protein. (767 aa)
	SPAM1	Hyaluronidase. (483 aa)
	SPAM1-2	Hyaluronidase. (479 aa)
	SPAM1-3	Hyaluronidase. (445 aa)
	LOC109984800	Hyaluronidase. (515 aa)
	LOC109984816	Hyaluronidase. (488 aa)
	ENSLBEP00000008410	Sulfatase domain-containing protein. (154 aa)
	LOC109993544	Hyaluronidase. (440 aa)
	LOC109993545	Uncharacterized protein. (280 aa)
	idua	Iduronidase alpha-L-. (634 aa)
	LOC109993542	Hyaluronidase. (536 aa)
	LOC109996946	N-acetylglucosaminidase, alpha. (749 aa)
	LOC109995362	Si:dkey-224e22.2; Belongs to the glycosyl hydrolase 35 family. (521 aa)
	sgsh	N-sulfoglucosamine sulfohydrolase (sulfamidase). (522 aa)
	ENSLBEP00000014723	Uncharacterized protein. (161 aa)
	galns	Galactosamine (N-acetyl)-6-sulfatase. (475 aa)
	LOC109982115	Beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b; Belongs to the glycosyl hydrolase 35 family. (597 aa)
	arsj	Arylsulfatase family, member J. (609 aa)
	ids	Iduronate 2-sulfatase. (527 aa)
	LOC110005888	Uncharacterized protein. (754 aa)
	sulf1	Sulfatase 1. (1157 aa)
	hexa	Beta-hexosaminidase. (502 aa)
	gusb	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (647 aa)
	LOC109983933	Extracellular sulfatase. (886 aa)
	HYAL2	Hyaluronidase. (476 aa)
	LOC109986366	Heparanase. (535 aa)
	arsk	Arylsulfatase family, member K. (567 aa)
	fam149b1	Family with sequence similarity 149 member B1. (618 aa)
	hexb	Beta-hexosaminidase. (555 aa)
	ARSB	Arylsulfatase B. (518 aa)
	LOC110000768	Glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b. (605 aa)
	ENSLBEP00000028967	Uncharacterized protein. (172 aa)
	ENSLBEP00000029547	Si:dkey-224e22.2; Belongs to the glycosyl hydrolase 35 family. (524 aa)
	LOC109997223	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (524 aa)
	LOC110003970	Galactosidase, beta 1-like. (589 aa)
	LOC109980615	Hyaluronidase. (440 aa)
	HYAL2-2	Hyaluronidase. (515 aa)
	LOC109993233	Si:dkey-192p21.6. (656 aa)
	hpse2	Heparanase 2. (575 aa)
	glb1	Beta-galactosidase. (647 aa)
	bod1l1	Uncharacterized protein. (1598 aa)
	arsi	Arylsulfatase family, member Ia. (576 aa)
	LOC109997365	Si:dkey-174i8.1. (559 aa)
	hgsnat	Heparan-alpha-glucosaminide N-acetyltransferase. (647 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARSB	ENSLBEP00000014723	ENSLBEP00000028751	ENSLBEP00000014723	Arylsulfatase B.	Uncharacterized protein.	0.561
ARSB	ENSLBEP00000029547	ENSLBEP00000028751	ENSLBEP00000029547	Arylsulfatase B.	Si:dkey-224e22.2; Belongs to the glycosyl hydrolase 35 family.	0.535
ARSB	HYAL2	ENSLBEP00000028751	ENSLBEP00000024748	Arylsulfatase B.	Hyaluronidase.	0.843
ARSB	HYAL2-2	ENSLBEP00000028751	ENSLBEP00000030751	Arylsulfatase B.	Hyaluronidase.	0.843
ARSB	LOC109980615	ENSLBEP00000028751	ENSLBEP00000030711	Arylsulfatase B.	Hyaluronidase.	0.840
ARSB	LOC109982115	ENSLBEP00000028751	ENSLBEP00000016458	Arylsulfatase B.	Beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b; Belongs to the glycosyl hydrolase 35 family.	0.535
ARSB	LOC109983933	ENSLBEP00000028751	ENSLBEP00000022105	Arylsulfatase B.	Extracellular sulfatase.	0.498
ARSB	LOC109984800	ENSLBEP00000028751	ENSLBEP00000004874	Arylsulfatase B.	Hyaluronidase.	0.843
ARSB	LOC109984816	ENSLBEP00000028751	ENSLBEP00000004923	Arylsulfatase B.	Hyaluronidase.	0.840
ARSB	LOC109985242	ENSLBEP00000028751	ENSLBEP00000001445	Arylsulfatase B.	Uncharacterized protein.	0.535
ARSB	LOC109993233	ENSLBEP00000028751	ENSLBEP00000031510	Arylsulfatase B.	Si:dkey-192p21.6.	0.561
ARSB	LOC109993544	ENSLBEP00000028751	ENSLBEP00000009761	Arylsulfatase B.	Hyaluronidase.	0.841
ARSB	LOC109995359	ENSLBEP00000028751	ENSLBEP00000011996	Arylsulfatase B.	Beta-galactosidase.	0.535
ARSB	LOC109995362	ENSLBEP00000028751	ENSLBEP00000012288	Arylsulfatase B.	Si:dkey-224e22.2; Belongs to the glycosyl hydrolase 35 family.	0.535
ARSB	LOC109997223	ENSLBEP00000028751	ENSLBEP00000030100	Arylsulfatase B.	N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family.	0.502
ARSB	LOC110000768	ENSLBEP00000028751	ENSLBEP00000028944	Arylsulfatase B.	Glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID), b.	0.505
ARSB	LOC110003970	ENSLBEP00000028751	ENSLBEP00000030401	Arylsulfatase B.	Galactosidase, beta 1-like.	0.573
ARSB	SPAM1	ENSLBEP00000028751	ENSLBEP00000002101	Arylsulfatase B.	Hyaluronidase.	0.843
ARSB	SPAM1-2	ENSLBEP00000028751	ENSLBEP00000004828	Arylsulfatase B.	Hyaluronidase.	0.841
ARSB	SPAM1-3	ENSLBEP00000028751	ENSLBEP00000004853	Arylsulfatase B.	Hyaluronidase.	0.840