(28 nodes) Butanoate metabolism network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gad2	Glutamate decarboxylase 2. (585 aa)
	LOC110006114	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (357 aa)
	LOC109984190	Zgc:113142; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (339 aa)
	hadha	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
	ENSLBEP00000037482	annotation not available (357 aa)
	hmgcll1	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. (336 aa)
	LOC109989786	Zgc:101569; Belongs to the enoyl-CoA hydratase/isomerase family. (309 aa)
	LOC109996161	Uncharacterized protein. (107 aa)
	bdh2	3-hydroxybutyrate dehydrogenase, type 2. (267 aa)
	LOC110001204	3-hydroxybutyrate dehydrogenase, type 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (361 aa)
	LOC109983872	Zgc:113054. (526 aa)
	gad1	Glutamate decarboxylase 1a. (592 aa)
	abat	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
	oxct1	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (527 aa)
	ehhadh	Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (721 aa)
	LOC109995230	Uncharacterized protein. (104 aa)
	ENSLBEP00000006227	Uncharacterized protein. (72 aa)
	LOC109995580	Glutamate decarboxylase 1b. (583 aa)
	LOC109989630	Uncharacterized protein. (123 aa)
	LOC109988426	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a; Belongs to the enoyl-CoA hydratase/isomerase family. (681 aa)
	l2hgdh	L-2-hydroxyglutarate dehydrogenase. (408 aa)
	aacs	Acetoacetyl-CoA synthetase. (667 aa)
	hadh	Hydroxyacyl-CoA dehydrogenase. (309 aa)
	LOC109978353	Aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase). (182 aa)
	echs1	Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (348 aa)
	acat2	Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
	hmgcl	3-hydroxy-3-methylglutaryl-CoA lyase. (334 aa)
	acat1	Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (419 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSLBEP00000006227	ENSLBEP00000037482	ENSLBEP00000006227	ENSLBEP00000037482	Uncharacterized protein.	annotation not available	0.980
ENSLBEP00000006227	LOC109978353	ENSLBEP00000006227	ENSLBEP00000018385	Uncharacterized protein.	Aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase).	0.629
ENSLBEP00000006227	LOC109983872	ENSLBEP00000006227	ENSLBEP00000025766	Uncharacterized protein.	Zgc:113054.	0.529
ENSLBEP00000006227	LOC109988426	ENSLBEP00000006227	ENSLBEP00000021908	Uncharacterized protein.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a; Belongs to the enoyl-CoA hydratase/isomerase family.	0.926
ENSLBEP00000006227	LOC109989786	ENSLBEP00000006227	ENSLBEP00000033314	Uncharacterized protein.	Zgc:101569; Belongs to the enoyl-CoA hydratase/isomerase family.	0.902
ENSLBEP00000006227	LOC110006114	ENSLBEP00000006227	ENSLBEP00000011276	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.980
ENSLBEP00000006227	aacs	ENSLBEP00000006227	ENSLBEP00000020508	Uncharacterized protein.	Acetoacetyl-CoA synthetase.	0.888
ENSLBEP00000006227	bdh2	ENSLBEP00000006227	ENSLBEP00000028030	Uncharacterized protein.	3-hydroxybutyrate dehydrogenase, type 2.	0.529
ENSLBEP00000006227	echs1	ENSLBEP00000006227	ENSLBEP00000018287	Uncharacterized protein.	Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.	0.920
ENSLBEP00000006227	ehhadh	ENSLBEP00000006227	ENSLBEP00000004694	Uncharacterized protein.	Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.957
ENSLBEP00000006227	hadh	ENSLBEP00000006227	ENSLBEP00000019441	Uncharacterized protein.	Hydroxyacyl-CoA dehydrogenase.	0.988
ENSLBEP00000006227	hadha	ENSLBEP00000006227	ENSLBEP00000008876	Uncharacterized protein.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha b; Belongs to the enoyl-CoA hydratase/isomerase family.	0.926
ENSLBEP00000006227	hmgcl	ENSLBEP00000006227	ENSLBEP00000017552	Uncharacterized protein.	3-hydroxy-3-methylglutaryl-CoA lyase.	0.813
ENSLBEP00000006227	hmgcll1	ENSLBEP00000006227	ENSLBEP00000033341	Uncharacterized protein.	3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1.	0.813
ENSLBEP00000006227	oxct1	ENSLBEP00000006227	ENSLBEP00000004501	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.904
ENSLBEP00000037482	ENSLBEP00000006227	ENSLBEP00000037482	ENSLBEP00000006227	annotation not available	Uncharacterized protein.	0.980
ENSLBEP00000037482	LOC109983872	ENSLBEP00000037482	ENSLBEP00000025766	annotation not available	Zgc:113054.	0.482
ENSLBEP00000037482	LOC109988426	ENSLBEP00000037482	ENSLBEP00000021908	annotation not available	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha a; Belongs to the enoyl-CoA hydratase/isomerase family.	0.772
ENSLBEP00000037482	LOC109989630	ENSLBEP00000037482	ENSLBEP00000022072	annotation not available	Uncharacterized protein.	0.982
ENSLBEP00000037482	LOC109989786	ENSLBEP00000037482	ENSLBEP00000033314	annotation not available	Zgc:101569; Belongs to the enoyl-CoA hydratase/isomerase family.	0.709