(109 nodes) PPAR signaling pathway network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ucp1	Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (306 aa)
	LOC109990230	Apolipoprotein A-IV a. (230 aa)
	LOC109990209	Uncharacterized protein. (246 aa)
	ubb	Ubiquitin B. (759 aa)
	pdpk1	3-phosphoinositide dependent protein kinase 1b. (538 aa)
	LOC109977269	Thiolase_N domain-containing protein. (421 aa)
	acsl6	AMP-binding domain-containing protein. (722 aa)
	LOC109992017	Antifreeze protein type IV. (149 aa)
	LOC109984291	Acyl-CoA synthetase long chain family member 1b. (682 aa)
	ppard	Peroxisome proliferator-activated receptor delta b. (510 aa)
	armc2	Armadillo repeat containing 2. (823 aa)
	LOC110004582	AMP-binding domain-containing protein. (620 aa)
	LOC110004594	AMP-binding domain-containing protein. (613 aa)
	acsl4	Acyl-CoA synthetase long chain family member 4a. (712 aa)
	fads2	Fatty acid desaturase 2. (438 aa)
	angptl4	Angiopoietin-like 4. (464 aa)
	LOC109989549	AMP-binding domain-containing protein. (635 aa)
	LOC109988384	Uncharacterized protein. (452 aa)
	ENSLBEP00000016716	Diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein). (82 aa)
	LOC110005811	Fatty acid binding protein 10b, liver basic. (136 aa)
	sik3	SIK family kinase 3. (1284 aa)
	LOC109991911	Uncharacterized protein. (261 aa)
	LOC109994770	Si:ch211-113j14.1; Belongs to the cytochrome P450 family. (488 aa)
	scp2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (535 aa)
	LOC110003738	Perilipin 6. (437 aa)
	LOC109997585	Fatty acid binding protein 6, ileal (gastrotropin). (127 aa)
	LOC110001108	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
	LOC109992983	Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (335 aa)
	LOC110006114	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (357 aa)
	LOC109997532	Carnitine palmitoyltransferase 1Cb; Belongs to the carnitine/choline acetyltransferase family. (785 aa)
	pck1	Phosphoenolpyruvate carboxykinase 1 (soluble). (624 aa)
	LOC109986633	Retinoid x receptor, beta b. (444 aa)
	acadl	Acyl-CoA dehydrogenase long chain. (424 aa)
	ENSLBEP00000008843	Acyl-CoA binding domain containing 7. (88 aa)
	LOC109996915	Si:dkey-91i10.3; Belongs to the cytochrome P450 family. (555 aa)
	ENSLBEP00000008733	Acyl-CoA oxidase 1, palmitoyl. (484 aa)
	LOC109987784	PLAT domain-containing protein. (512 aa)
	lpl	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (516 aa)
	LOC109990010	Aquaporin 10a; Belongs to the MIP/aquaporin (TC 1.A.8) family. (278 aa)
	UFC1	Ubiquitin-fold modifier conjugating enzyme 1. (158 aa)
	LOC110001682	Acyl-CoA synthetase long chain family member 2. (716 aa)
	FABP6	Fatty acid binding protein 6. (141 aa)
	slc27a4	Solute carrier family 27 member 4. (643 aa)
	LOC109981472	Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa)
	LOC109981428	Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (312 aa)
	ENSLBEP00000004927	Uncharacterized protein. (95 aa)
	ILK	Integrin linked kinase. (452 aa)
	ENSLBEP00000004707	Sorbin and SH3 domain containing 3. (470 aa)
	ehhadh	Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (721 aa)
	PPARG	Peroxisome proliferator activated receptor gamma. (551 aa)
	sorbs2	Sorbin and SH3 domain containing 2a. (1766 aa)
	me1	Malic enzyme. (588 aa)
	LOC109982478	Fatty acid binding protein 3, muscle and heart; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (121 aa)
	LOC109989553	Carnitine palmitoyltransferase 1Ab (liver); Belongs to the carnitine/choline acetyltransferase family. (772 aa)
	LOC110004259	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (448 aa)
	me3	Malic enzyme. (618 aa)
	pkib	Si:ch211-255i3.4. (127 aa)
	FABP7	Fatty acid binding protein 7; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	cpt2	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (664 aa)
	LOC109983497	Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family. (519 aa)
	LOC109980817	Aquaporin 7; Belongs to the MIP/aquaporin (TC 1.A.8) family. (309 aa)
	LOC109981894	Stearoyl-CoA desaturase b; Belongs to the fatty acid desaturase type 1 family. (438 aa)
	acadm	Acyl-CoA dehydrogenase medium chain. (424 aa)
	LOC110000515	Fibrinogen C-terminal domain-containing protein. (399 aa)
	LOC109981845	Acyl-CoA synthetase long chain family member 5. (631 aa)
	DBI	ACB domain-containing protein. (63 aa)
	LOC109996779	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (311 aa)
	nr1h3	Nuclear receptor subfamily 1, group H, member 3. (464 aa)
	cd36	CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. (470 aa)
	LOC109995000	Aquaporin 10b; Belongs to the MIP/aquaporin (TC 1.A.8) family. (423 aa)
	LOC109991631	AMP-binding domain-containing protein. (723 aa)
	acsbg2	Acyl-CoA synthetase bubblegum family member 2. (766 aa)
	LOC109984497	Uncharacterized protein. (127 aa)
	LOC110001430	Uncharacterized protein; Belongs to the FGGY kinase family. (567 aa)
	LOC109983460	Uncharacterized protein; Belongs to the FGGY kinase family. (540 aa)
	LOC109987481	Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (633 aa)
	FABP2	Fatty acid binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	ENSLBEP00000037482	annotation not available (357 aa)
	ppara	Peroxisome proliferator-activated receptor alpha a. (474 aa)
	LOC110002118	Carnitine palmitoyltransferase 1B (muscle); Belongs to the carnitine/choline acetyltransferase family. (786 aa)
	LOC109987760	Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family. (794 aa)
	acsl1	Acyl-CoA synthetase long chain family member 1a. (697 aa)
	LOC109994973	Fatty acid binding protein 11b; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
	LOC109987023	Uncharacterized protein. (621 aa)
	LOC109995609	AMP-binding domain-containing protein. (618 aa)
	LOC109987006	Solute carrier family 27 member 2a. (617 aa)
	slc27a6	Solute carrier family 27 member 6. (623 aa)
	LOC109993221	Sorbin and SH3 domain containing 1. (861 aa)
	slc27a1	Solute carrier family 27 member 1a. (651 aa)
	LOC109984045	Acyl-CoA synthetase long chain family member 3b. (711 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha b. (468 aa)
	LOC109991529	Fatty acid binding protein 2, intestinal; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
	rxra	Retinoid X receptor, alpha a. (467 aa)
	ENSLBEP00000029271	NR LBD domain-containing protein. (144 aa)
	LOC110001923	Uncharacterized protein. (471 aa)
	ENSLBEP00000028802	Uncharacterized protein. (135 aa)
	LOC109986369	Ubiquitin-fold modifier-conjugating enzyme 1-like. (158 aa)
	acox3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (765 aa)
	plin2	Perilipin; Belongs to the perilipin family. (459 aa)
	LOC109998300	Fatty acid binding protein 7, brain, a; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	plin3	Perilipin; Belongs to the perilipin family. (428 aa)
	ENSLBEP00000025196	ANK_REP_REGION domain-containing protein. (154 aa)
	LOC109994312	Uncharacterized protein. (467 aa)
	fabp1	Fatty acid binding protein 1b, tandem duplicate 1. (127 aa)
	LOC109997762	Fatty acid binding protein 11a; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
	acsl3	AMP-binding domain-containing protein. (719 aa)
	LOC109975216	Apolipoprotein A-I-like. (246 aa)
	LOC109975217	Uncharacterized protein. (230 aa)
	LOC109981488	Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (513 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DBI	ENSLBEP00000008733	ENSLBEP00000034245	ENSLBEP00000008733	ACB domain-containing protein.	Acyl-CoA oxidase 1, palmitoyl.	0.744
DBI	ENSLBEP00000008843	ENSLBEP00000034245	ENSLBEP00000008843	ACB domain-containing protein.	Acyl-CoA binding domain containing 7.	0.835
DBI	LOC109977269	ENSLBEP00000034245	ENSLBEP00000020765	ACB domain-containing protein.	Thiolase_N domain-containing protein.	0.734
DBI	LOC110001108	ENSLBEP00000034245	ENSLBEP00000013376	ACB domain-containing protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.744
DBI	LOC110004259	ENSLBEP00000034245	ENSLBEP00000002523	ACB domain-containing protein.	Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.	0.734
DBI	acadl	ENSLBEP00000034245	ENSLBEP00000009663	ACB domain-containing protein.	Acyl-CoA dehydrogenase long chain.	0.666
DBI	acadm	ENSLBEP00000034245	ENSLBEP00000000826	ACB domain-containing protein.	Acyl-CoA dehydrogenase medium chain.	0.683
DBI	acox3	ENSLBEP00000034245	ENSLBEP00000026826	ACB domain-containing protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.729
DBI	ehhadh	ENSLBEP00000034245	ENSLBEP00000004694	ACB domain-containing protein.	Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.602
DBI	scp2	ENSLBEP00000034245	ENSLBEP00000013945	ACB domain-containing protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.628
DBI	ubb	ENSLBEP00000034245	ENSLBEP00000021236	ACB domain-containing protein.	Ubiquitin B.	0.421
ENSLBEP00000004927	ENSLBEP00000008733	ENSLBEP00000004927	ENSLBEP00000008733	Uncharacterized protein.	Acyl-CoA oxidase 1, palmitoyl.	0.569
ENSLBEP00000004927	LOC109983497	ENSLBEP00000004927	ENSLBEP00000001169	Uncharacterized protein.	Cytochrome P450, family 27, subfamily A, polypeptide 7; Belongs to the cytochrome P450 family.	0.527
ENSLBEP00000004927	LOC109989549	ENSLBEP00000004927	ENSLBEP00000017214	Uncharacterized protein.	AMP-binding domain-containing protein.	0.687
ENSLBEP00000004927	LOC109994770	ENSLBEP00000004927	ENSLBEP00000014818	Uncharacterized protein.	Si:ch211-113j14.1; Belongs to the cytochrome P450 family.	0.527
ENSLBEP00000004927	LOC109996915	ENSLBEP00000004927	ENSLBEP00000008841	Uncharacterized protein.	Si:dkey-91i10.3; Belongs to the cytochrome P450 family.	0.527
ENSLBEP00000004927	LOC110001108	ENSLBEP00000004927	ENSLBEP00000013376	Uncharacterized protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.569
ENSLBEP00000004927	LOC110004594	ENSLBEP00000004927	ENSLBEP00000018807	Uncharacterized protein.	AMP-binding domain-containing protein.	0.680
ENSLBEP00000004927	acadl	ENSLBEP00000004927	ENSLBEP00000009663	Uncharacterized protein.	Acyl-CoA dehydrogenase long chain.	0.491
ENSLBEP00000004927	acadm	ENSLBEP00000004927	ENSLBEP00000000826	Uncharacterized protein.	Acyl-CoA dehydrogenase medium chain.	0.442