STRINGSTRING
LOC109988297 LOC109988297 LOC109977533 LOC109977533 LOC109995233 LOC109995233 LOC109987702 LOC109987702 SRC SRC LOC110000401 LOC110000401 gem gem LOC109989970 LOC109989970 LOC109997114 LOC109997114 LOC109983533 LOC109983533 hras hras ENSLBEP00000002343 ENSLBEP00000002343 LOC109997393 LOC109997393 LOC109988782 LOC109988782 ptk2b ptk2b ENSLBEP00000001908 ENSLBEP00000001908 LOC109984063 LOC109984063 LOC109992271 LOC109992271 map3k2 map3k2 LOC109979512 LOC109979512 LOC109994562 LOC109994562 map2k4 map2k4 LOC109984593 LOC109984593 LOC109984590 LOC109984590 LOC109988080 LOC109988080 LOC109997357 LOC109997357 mapk11 mapk11 LOC110004156 LOC110004156 LOC109987527 LOC109987527 LOC110002092 LOC110002092 kras kras LOC109979917 LOC109979917 ADCY9 ADCY9 LOC109996767 LOC109996767 LOC109993330 LOC109993330 LOC109983419 LOC109983419 pla2g4a pla2g4a LOC110003520 LOC110003520 LOC109990942 LOC109990942 PLCB2 PLCB2 LOC110001378 LOC110001378 LOC109990898 LOC109990898 LOC109985849 LOC109985849 PLCB1 PLCB1 REM1 REM1 LOC110000085 LOC110000085 PLCB4 PLCB4 LOC109998393 LOC109998393 LOC109999686 LOC109999686 LOC109987681 LOC109987681 LOC109989210 LOC109989210 ENSLBEP00000031813 ENSLBEP00000031813 LOC109996231 LOC109996231 LOC109998395 LOC109998395 adcy7 adcy7 LOC110003296 LOC110003296 ENSLBEP00000029664 ENSLBEP00000029664 LOC109995592 LOC109995592 LOC109996180 LOC109996180 PRKCB PRKCB LOC109988511 LOC109988511 adcy2 adcy2 LOC109990841 LOC109990841 LOC109999597 LOC109999597 LOC109992267 LOC109992267 ENSLBEP00000027326 ENSLBEP00000027326 ENSLBEP00000027248 ENSLBEP00000027248 LOC109992800 LOC109992800 LOC109998863 LOC109998863 LOC109997137 LOC109997137 adcy6 adcy6 LOC110003094 LOC110003094 LOC109983881 LOC109983881 LOC110000165 LOC110000165 itpr1 itpr1 LOC109986823 LOC109986823 prkcd prkcd LOC109982751 LOC109982751 mapk1 mapk1 LOC109985061 LOC109985061 egfr egfr grb2 grb2 LOC109990779 LOC109990779 sos2 sos2 LOC109998241 LOC109998241 LOC110003801 LOC110003801 LOC109997072 LOC109997072 LOC109993687 LOC109993687 LOC109993114 LOC109993114 plcb3 plcb3 LOC109977256 LOC109977256 map2k1 map2k1 ATF4 ATF4 LOC109994795 LOC109994795 LOC109990744 LOC109990744 ENSLBEP00000019576 ENSLBEP00000019576 CSDE1 CSDE1 LOC109999449 LOC109999449 ENSLBEP00000018519 ENSLBEP00000018519 LOC109985578 LOC109985578 LOC109989567 LOC109989567 ENSLBEP00000017391 ENSLBEP00000017391 ENSLBEP00000017353 ENSLBEP00000017353 LOC109994796 LOC109994796 ENSLBEP00000017302 ENSLBEP00000017302 LOC109994200 LOC109994200 LOC109991316 LOC109991316 LOC109997643 LOC109997643 LOC110004577 LOC110004577 PRKCA PRKCA LOC109995395 LOC109995395 LOC109991029 LOC109991029 map3k4 map3k4 mmp2 mmp2 ENSLBEP00000015105 ENSLBEP00000015105 jun jun prkacb prkacb LOC109991266 LOC109991266 ptx3 ptx3 rrad rrad ELK3 ELK3 CDC42 CDC42 LOC109996988 LOC109996988 LOC109984231 LOC109984231 LOC109994148 LOC109994148 LOC110006193 LOC110006193 LOC109989518 LOC109989518 LOC109999960 LOC109999960 ENSLBEP00000013304 ENSLBEP00000013304 LOC109998103 LOC109998103 map2k7 map2k7 ENSLBEP00000012398 ENSLBEP00000012398 LOC109981499 LOC109981499 CACNA1D CACNA1D ENSLBEP00000011375 ENSLBEP00000011375 LOC110000507 LOC110000507 ENSLBEP00000010472 ENSLBEP00000010472 ENSLBEP00000010414 ENSLBEP00000010414 LOC109988324 LOC109988324 LOC109999319 LOC109999319 ENSLBEP00000010218 ENSLBEP00000010218 ENSLBEP00000009978 ENSLBEP00000009978 ENSLBEP00000009872 ENSLBEP00000009872 ENSLBEP00000009713 ENSLBEP00000009713 ENSLBEP00000009639 ENSLBEP00000009639 GNRHR GNRHR LOC109999298 LOC109999298 LOC109993502 LOC109993502 LOC110001032 LOC110001032 LOC109983664 LOC109983664 LOC109997988 LOC109997988 egr1 egr1 map3k3 map3k3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC109988297Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
LOC109977533CaMKII_AD domain-containing protein. (153 aa)
LOC109995233Calmodulin-like 4b. (149 aa)
LOC109987702Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
SRCTyrosine-protein kinase. (549 aa)
LOC110000401Luteinizing hormone, beta polypeptide. (149 aa)
gemGTP binding protein overexpressed in skeletal muscle. (294 aa)
LOC109989970Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2. (519 aa)
LOC109997114Matrix metallopeptidase 14b (membrane-inserted). (626 aa)
LOC109983533Calcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (477 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
ENSLBEP00000002343Ras-GEF domain-containing protein. (394 aa)
LOC109997393Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1573 aa)
LOC109988782Matrix metallopeptidase 14a (membrane-inserted). (562 aa)
ptk2bProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (993 aa)
ENSLBEP00000001908Protein kinase domain-containing protein. (112 aa)
LOC109984063Mitogen-activated protein kinase kinase 2b. (394 aa)
LOC109992271Mitogen-activated protein kinase. (381 aa)
map3k2Mitogen-activated protein kinase kinase kinase 2. (608 aa)
LOC109979512Uncharacterized protein. (764 aa)
LOC109994562Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (97 aa)
map2k4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (432 aa)
LOC109984593ETS transcription factor ELK3. (400 aa)
LOC109984590Mitogen-activated protein kinase. (357 aa)
LOC109988080Heparin-binding EGF-like growth factor a. (239 aa)
LOC109997357Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2. (554 aa)
mapk11Mitogen-activated protein kinase. (361 aa)
LOC110004156Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (925 aa)
LOC109987527Gonadotropin releasing hormone receptor 1; Belongs to the G-protein coupled receptor 1 family. (382 aa)
LOC110002092Si:ch211-132f19.7; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1154 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
LOC109979917Ion_trans domain-containing protein. (169 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1449 aa)
LOC109996767Calmodulin. (149 aa)
LOC109993330Protein kinase domain-containing protein. (614 aa)
LOC109983419Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (688 aa)
pla2g4aPhospholipase A2. (749 aa)
LOC110003520Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (180 aa)
LOC109990942Cys_knot domain-containing protein. (127 aa)
PLCB2Phosphoinositide phospholipase C. (1053 aa)
LOC110001378Son of sevenless homolog 1 (Drosophila). (967 aa)
LOC109990898Adenylate cyclase 2b (brain); Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (847 aa)
LOC109985849Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (779 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1142 aa)
REM1RRAD and GEM like GTPase 1. (311 aa)
LOC110000085Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
LOC109998393Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (391 aa)
LOC109999686Bifunctional peptidase and (3S)-lysyl hydroxylase Jmjd7-like. (311 aa)
LOC109987681Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1167 aa)
LOC109989210Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (390 aa)
ENSLBEP00000031813Ins145_P3_rec domain-containing protein. (164 aa)
LOC109996231Tyrosine-protein kinase. (439 aa)
LOC109998395Zgc:55558. (187 aa)
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1114 aa)
LOC110003296Uncharacterized protein. (138 aa)
ENSLBEP00000029664Protein kinase domain-containing protein. (153 aa)
LOC109995592Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1130 aa)
LOC109996180Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (359 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
LOC109988511JunE proto-oncogene, AP-1 transcription factor subunit. (344 aa)
adcy2Adenylate cyclase 2a; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (858 aa)
LOC109990841Uncharacterized protein; Belongs to the calmodulin family. (209 aa)
LOC109999597Phospholipase. (960 aa)
LOC109992267Receptor protein-tyrosine kinase. (1184 aa)
ENSLBEP00000027326Uncharacterized protein. (478 aa)
ENSLBEP00000027248Uncharacterized protein. (355 aa)
LOC109992800Mitogen-activated protein kinase kinase kinase 22. (621 aa)
LOC109998863Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1107 aa)
LOC109997137Uncharacterized protein. (359 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1209 aa)
LOC110003094Jumonji domain containing 7. (311 aa)
LOC109983881Inositol 1,4,5-trisphosphate receptor, type 1b. (2690 aa)
LOC1100001651-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
itpr1Inositol 1,4,5-trisphosphate receptor, type 1a. (2706 aa)
LOC109986823Calmodulin-like 4a. (153 aa)
prkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)
LOC109982751Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (399 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (371 aa)
LOC109985061Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1078 aa)
egfrReceptor protein-tyrosine kinase. (1196 aa)
grb2Growth factor receptor bound protein 2. (230 aa)
LOC109990779Mitogen-activated protein kinase. (476 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1067 aa)
LOC109998241Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2165 aa)
LOC110003801Inositol 1,4,5-trisphosphate receptor, type 2. (2003 aa)
LOC109997072Phospholipase. (898 aa)
LOC109993687Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
LOC109993114Phospholipase. (1038 aa)
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1172 aa)
LOC109977256PLA2c domain-containing protein. (624 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (352 aa)
ATF4Activating transcription factor 4. (432 aa)
LOC109994795Mitogen-activated protein kinase. (360 aa)
LOC109990744Mitogen-activated protein kinase. (381 aa)
ENSLBEP00000019576Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (142 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (869 aa)
LOC109999449Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (402 aa)
ENSLBEP00000018519CaMKII_AD domain-containing protein. (211 aa)
LOC109985578Mitogen-activated protein kinase. (363 aa)
LOC109989567Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1408 aa)
ENSLBEP00000017391Uncharacterized protein. (271 aa)
ENSLBEP00000017353Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (648 aa)
LOC109994796Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1156 aa)
ENSLBEP00000017302G_PROTEIN_RECEP_F1_2 domain-containing protein. (414 aa)
LOC109994200Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1166 aa)
LOC109991316Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1; Belongs to the protein kinase superfamily. (462 aa)
LOC109997643Protein kinase, cAMP-dependent, catalytic, beta b; Belongs to the protein kinase superfamily. (351 aa)
LOC110004577Inositol 1,4,5-trisphosphate receptor, type 3. (1352 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
LOC109995395Uncharacterized protein. (191 aa)
LOC109991029GRB2 related adaptor protein 2b. (237 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1594 aa)
mmp2Matrix metallopeptidase 2. (658 aa)
ENSLBEP00000015105Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (291 aa)
junBZIP domain-containing protein; Belongs to the bZIP family. (323 aa)
prkacbUncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
LOC109991266Activating transcription factor 4a. (443 aa)
ptx3Pentraxin 3, long b. (464 aa)
rradRas-related associated with diabetes. (309 aa)
ELK3ETS transcription factor ELK3. (142 aa)
CDC42Cell division cycle 42. (203 aa)
LOC109996988Activating transcription factor 4b. (431 aa)
LOC109984231Mitogen-activated protein kinase. (361 aa)
LOC109994148Cell division cycle 42. (191 aa)
LOC110006193Uncharacterized protein. (409 aa)
LOC109989518Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family. (231 aa)
LOC109999960Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (90 aa)
ENSLBEP00000013304PLA2c domain-containing protein. (412 aa)
LOC109998103PLA2c domain-containing protein. (595 aa)
map2k7Mitogen-activated protein kinase kinase 7. (423 aa)
ENSLBEP00000012398EF-hand domain-containing protein. (275 aa)
LOC109981499Mitogen-activated protein kinase. (364 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2108 aa)
ENSLBEP00000011375Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1804 aa)
LOC110000507Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1112 aa)
ENSLBEP00000010472Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (320 aa)
ENSLBEP00000010414Ion_trans domain-containing protein. (194 aa)
LOC109988324Mitogen-activated protein kinase. (361 aa)
LOC109999319Uncharacterized protein. (923 aa)
ENSLBEP00000010218Protein kinase domain-containing protein. (138 aa)
ENSLBEP00000009978ETS domain-containing protein. (165 aa)
ENSLBEP00000009872Uncharacterized protein. (77 aa)
ENSLBEP00000009713Uncharacterized protein. (96 aa)
ENSLBEP00000009639Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (314 aa)
GNRHRGonadotropin releasing hormone receptor. (403 aa)
LOC109999298G_PROTEIN_RECEP_F1_2 domain-containing protein. (394 aa)
LOC109993502Mitogen-activated protein kinase. (369 aa)
LOC110001032Uncharacterized protein. (359 aa)
LOC109983664Calmodulin 3a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
LOC109997988GRB2 related adaptor protein 2a. (279 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (510 aa)
map3k3Mitogen-activated protein kinase kinase kinase 3. (618 aa)
Your Current Organism:
Labrus bergylta
NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse
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