(108 nodes) Adipocytokine signaling pathway network (Labrus bergylta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	acsl1	Acyl-CoA synthetase long chain family member 1a. (697 aa)
	ENSLBEP00000032583	Uncharacterized protein. (263 aa)
	PRKAB2	5'-AMP-activated protein kinase subunit beta-2-like. (268 aa)
	LOC109991608	Inhibitor of nuclear factor kappa B kinase subunit beta. (704 aa)
	prkaa1	Non-specific serine/threonine protein kinase. (573 aa)
	POMC	Proopiomelanocortin. (218 aa)
	LOC109987760	Uncharacterized protein; Belongs to the carnitine/choline acetyltransferase family. (794 aa)
	LOC109998959	Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (332 aa)
	LOC109993293	Si:ch211-284e13.4. (1158 aa)
	LOC109991634	Tyrosine-protein kinase. (1116 aa)
	cd36	CD36 molecule (thrombospondin receptor); Belongs to the CD36 family. (470 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (411 aa)
	LOC109993306	Suppressor of cytokine signaling 3. (409 aa)
	LOC109991631	AMP-binding domain-containing protein. (723 aa)
	ENSLBEP00000035319	Insulin receptor substrate 4a. (867 aa)
	acsbg2	Acyl-CoA synthetase bubblegum family member 2. (766 aa)
	LOC109987481	Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (633 aa)
	SLC2A4	Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (507 aa)
	g6pc3	Glucose 6 phosphatase, catalytic, 3. (338 aa)
	LOC109980706	Si:ch73-335l21.1. (1285 aa)
	ENSLBEP00000037820	Agouti domain-containing protein. (133 aa)
	ppara	Peroxisome proliferator-activated receptor alpha a. (474 aa)
	LOC110002118	Carnitine palmitoyltransferase 1B (muscle); Belongs to the carnitine/choline acetyltransferase family. (786 aa)
	G6PC2	Glucose-6-phosphatase catalytic subunit 2. (479 aa)
	nostrin	Nitric oxide synthase trafficking. (574 aa)
	LOC110001682	Acyl-CoA synthetase long chain family member 2. (716 aa)
	LOC109976821	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (412 aa)
	npy	Neuropeptide Y. (99 aa)
	LOC109981845	Acyl-CoA synthetase long chain family member 5. (631 aa)
	LOC109992271	Mitogen-activated protein kinase. (381 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (438 aa)
	NPY	Neuropeptide Y. (100 aa)
	LOC109995112	TNF receptor-associated factor. (492 aa)
	LOC110005520	Protein kinase AMP-activated non-catalytic subunit beta 2. (268 aa)
	LOC109988232	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (455 aa)
	LOC109989553	Carnitine palmitoyltransferase 1Ab (liver); Belongs to the carnitine/choline acetyltransferase family. (772 aa)
	LOC109993466	V-rel avian reticuloendotheliosis viral oncogene homolog A. (633 aa)
	LOC109987103	Si:ch73-62l21.1. (593 aa)
	ENSLBEP00000004299	FERM domain-containing protein. (124 aa)
	ENSLBEP00000004314	Protein kinase domain-containing protein. (82 aa)
	ENSLBEP00000004327	Protein kinase domain-containing protein. (192 aa)
	stat3	Signal transducer and activator of transcription. (708 aa)
	ENSLBEP00000005638	IKKbetaNEMObind domain-containing protein. (509 aa)
	LOC109983659	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (308 aa)
	lepr	Leptin receptor. (1144 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (762 aa)
	LOC109993502	Mitogen-activated protein kinase. (369 aa)
	ENSLBEP00000008892	Uncharacterized protein. (305 aa)
	LOC110001065	Agouti domain-containing protein. (143 aa)
	LOC109986633	Retinoid x receptor, beta b. (444 aa)
	pck1	Phosphoenolpyruvate carboxykinase 1 (soluble). (624 aa)
	LOC109997215	Agouti signaling protein, nonagouti homolog (mouse) 2b. (117 aa)
	LOC109997532	Carnitine palmitoyltransferase 1Cb; Belongs to the carnitine/choline acetyltransferase family. (785 aa)
	LOC109982042	Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (330 aa)
	prkaa2	Non-specific serine/threonine protein kinase. (557 aa)
	nfkbie	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon. (345 aa)
	g6pc	Glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2. (362 aa)
	LOC109992407	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (352 aa)
	acacb	Acetyl-CoA carboxylase beta. (2403 aa)
	LOC109994176	Uncharacterized protein. (235 aa)
	LOC109997858	Uncharacterized protein. (158 aa)
	ENSLBEP00000017712	Protein kinase domain-containing protein. (679 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2492 aa)
	acsl4	Acyl-CoA synthetase long chain family member 4a. (712 aa)
	LOC109985568	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa)
	LOC109996569	Insulin receptor substrate 2a. (1029 aa)
	LOC110002960	MFS domain-containing protein; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (481 aa)
	LOC109981577	Solute carrier family 2 member 1a; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (493 aa)
	adipor2	Adiponectin receptor 2. (376 aa)
	LOC109993689	Solute carrier family 2 member 3b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (517 aa)
	LOC109990744	Mitogen-activated protein kinase. (381 aa)
	LOC110000055	Solute carrier family 2 member 3a; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (532 aa)
	LOC109984291	Acyl-CoA synthetase long chain family member 1b. (682 aa)
	acsl6	AMP-binding domain-containing protein. (722 aa)
	ikbkg	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (567 aa)
	LOC109990779	Mitogen-activated protein kinase. (476 aa)
	LOC109996590	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (519 aa)
	acsl3	AMP-binding domain-containing protein. (719 aa)
	ppargc1a	Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. (989 aa)
	prkag1	Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (372 aa)
	LOC109986666	Protein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (544 aa)
	LOC110003847	Insulin receptor substrate 2b. (1059 aa)
	LOC109992084	Non-specific serine/threonine protein kinase. (506 aa)
	LOC109996204	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (410 aa)
	LOC109994312	Uncharacterized protein. (467 aa)
	nfkb1	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (843 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha b. (468 aa)
	rxra	Retinoid X receptor, alpha a. (467 aa)
	LOC110001923	Uncharacterized protein. (471 aa)
	LOC109993202	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (318 aa)
	LOC109981688	Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (269 aa)
	LOC110005997	Uncharacterized protein. (218 aa)
	ENSLBEP00000028454	Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (108 aa)
	ENSLBEP00000028421	Protein kinase, AMP-activated, gamma 3b non-catalytic subunit. (156 aa)
	LOC109999600	Solute carrier family 2 member 2; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (505 aa)
	LOC109984045	Acyl-CoA synthetase long chain family member 3b. (711 aa)
	prkcq	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (700 aa)
	socs3	Suppressor of cytokine signaling 3a. (206 aa)
	adipor1	Adiponectin receptor 1a. (376 aa)
	LOC109998929	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (598 aa)
	LOC109993885	RHD domain-containing protein. (601 aa)
	LOC109982881	Uncharacterized protein. (396 aa)
	LOC109981734	Solute carrier family 2 member 1b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (497 aa)
	LOC109981196	Tyrosine-protein kinase. (1130 aa)
	LOC109980562	Uncharacterized protein. (503 aa)
	tradd	Tnfrsf1a-associated via death domain. (291 aa)

Your Current Organism:

Labrus bergylta

NCBI taxonomy Id: 56723
Other names: L. bergylta, ballan wrasse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHUK	ENSLBEP00000005638	ENSLBEP00000008404	ENSLBEP00000005638	Component of inhibitor of nuclear factor kappa B kinase complex.	IKKbetaNEMObind domain-containing protein.	0.833
CHUK	ENSLBEP00000008892	ENSLBEP00000008404	ENSLBEP00000008892	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.805
CHUK	ENSLBEP00000017712	ENSLBEP00000008404	ENSLBEP00000017712	Component of inhibitor of nuclear factor kappa B kinase complex.	Protein kinase domain-containing protein.	0.834
CHUK	ENSLBEP00000035319	ENSLBEP00000008404	ENSLBEP00000035319	Component of inhibitor of nuclear factor kappa B kinase complex.	Insulin receptor substrate 4a.	0.875
CHUK	LOC109976821	ENSLBEP00000008404	ENSLBEP00000006838	Component of inhibitor of nuclear factor kappa B kinase complex.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.834
CHUK	LOC109980706	ENSLBEP00000008404	ENSLBEP00000037796	Component of inhibitor of nuclear factor kappa B kinase complex.	Si:ch73-335l21.1.	0.875
CHUK	LOC109982881	ENSLBEP00000008404	ENSLBEP00000030967	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.805
CHUK	LOC109983659	ENSLBEP00000008404	ENSLBEP00000007019	Component of inhibitor of nuclear factor kappa B kinase complex.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	0.914
CHUK	LOC109988232	ENSLBEP00000008404	ENSLBEP00000002317	Component of inhibitor of nuclear factor kappa B kinase complex.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.888
CHUK	LOC109991608	ENSLBEP00000008404	ENSLBEP00000033093	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.859
CHUK	LOC109992084	ENSLBEP00000008404	ENSLBEP00000024516	Component of inhibitor of nuclear factor kappa B kinase complex.	Non-specific serine/threonine protein kinase.	0.893
CHUK	LOC109993202	ENSLBEP00000008404	ENSLBEP00000029088	Component of inhibitor of nuclear factor kappa B kinase complex.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.893
CHUK	LOC109993293	ENSLBEP00000008404	ENSLBEP00000034012	Component of inhibitor of nuclear factor kappa B kinase complex.	Si:ch211-284e13.4.	0.875
CHUK	LOC109993466	ENSLBEP00000008404	ENSLBEP00000003392	Component of inhibitor of nuclear factor kappa B kinase complex.	V-rel avian reticuloendotheliosis viral oncogene homolog A.	0.761
CHUK	LOC109993885	ENSLBEP00000008404	ENSLBEP00000030766	Component of inhibitor of nuclear factor kappa B kinase complex.	RHD domain-containing protein.	0.761
CHUK	LOC109995112	ENSLBEP00000008404	ENSLBEP00000001259	Component of inhibitor of nuclear factor kappa B kinase complex.	TNF receptor-associated factor.	0.681
CHUK	LOC109996204	ENSLBEP00000008404	ENSLBEP00000029818	Component of inhibitor of nuclear factor kappa B kinase complex.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.888
CHUK	LOC109996569	ENSLBEP00000008404	ENSLBEP00000018984	Component of inhibitor of nuclear factor kappa B kinase complex.	Insulin receptor substrate 2a.	0.875
CHUK	LOC109996590	ENSLBEP00000008404	ENSLBEP00000023058	Component of inhibitor of nuclear factor kappa B kinase complex.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.681
CHUK	LOC109998929	ENSLBEP00000008404	ENSLBEP00000030749	Component of inhibitor of nuclear factor kappa B kinase complex.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.681