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SYN_00088 SYN_00088 leuA leuA leuC leuC leuD leuD SYN_00115 SYN_00115 SYN_00154 SYN_00154 SYN_00155 SYN_00155 SYN_00156 SYN_00156 SYN_00157 SYN_00157 SYN_00316 SYN_00316 SYN_00691 SYN_00691 SYN_00692 SYN_00692 SYN_00693 SYN_00693 SYN_00694 SYN_00694 SYN_01040 SYN_01040 SYN_01041 SYN_01041 SYN_01431 SYN_01431 SYN_01434 SYN_01434 ilvD ilvD SYN_01709 SYN_01709 SYN_01710 SYN_01710 SYN_01711 SYN_01711 SYN_01712 SYN_01712 SYN_01713 SYN_01713 SYN_01965 SYN_01965 SYN_02086 SYN_02086 SYN_02194 SYN_02194 SYN_02201 SYN_02201 SYN_02360 SYN_02360 SYN_02497 SYN_02497 SYN_02498 SYN_02498 SYN_02499 SYN_02499 SYN_02500 SYN_02500 sucC sucC sucD sucD SYN_02536 SYN_02536 SYN_02966 SYN_02966 SYN_03161 SYN_03161 SYN_03162 SYN_03162 SYN_03163 SYN_03163 SYN_03227 SYN_03227
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYN_000883-isopropylmalate dehydrogenase. (360 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (516 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (420 aa)
leuDAconitase C-terminal domain protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (164 aa)
SYN_00115Na+-transporting decarboxylase, beta subunit. (400 aa)
SYN_00154Pyruvate:ferredoxin oxidoreductase beta subunit. (323 aa)
SYN_00155Pyruvate:ferredoxin oxidoreductase alpha subunit. (391 aa)
SYN_00156Pyruvate:ferredoxin oxidoreductase delta subunit. (113 aa)
SYN_00157Pyruvate:ferredoxin oxidoreductase gamma subunit. (181 aa)
SYN_00316(s)-2-hydroxy-acid oxidase chain D. (509 aa)
SYN_00691Pyruvate synthase subunit. (304 aa)
SYN_00692Pyruvate synthase alpha chain. (370 aa)
SYN_00693Pyruvate synthase gamma chain. (175 aa)
SYN_00694Pyruvate synthase delta subunit. (83 aa)
SYN_01040Pyruvate carboxylase carboxyltransferase subunit. (653 aa)
SYN_01041Pyruvate carboxylase biotin carboxylase subunit. (486 aa)
SYN_01431glutaconyl-CoA decarboxylase beta subunit. (448 aa)
SYN_01434Na+-translocating decarboxylase, beta subunit. (406 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (553 aa)
SYN_01709Ketol-acid reductoisomerase / 2-dehydropantoate 2-reductase; Bifunctional. (348 aa)
SYN_01710Acetolactate synthase small subunit. (157 aa)
SYN_01711Acetolactate synthase large subunit. (568 aa)
SYN_01712Acetolactate synthase small subunit. (166 aa)
SYN_01713Acetolactate synthase large subunit. (557 aa)
SYN_01965Acetolactate synthase. (526 aa)
SYN_02086Phosphoenolpyruvate carboxykinase (ATP). (549 aa)
SYN_021942-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (532 aa)
SYN_02201Pyruvate dehydrogenase (ferredoxin/flavodoxin-dependent). (1172 aa)
SYN_02360acetyl-CoA hydrolase/transferase. (435 aa)
SYN_02497Ferridoxin. (105 aa)
SYN_024982-oxoglutarate synthase subunit. (380 aa)
SYN_024992-oxoglutarate synthase subunit. (309 aa)
SYN_02500Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (193 aa)
sucCsuccinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (398 aa)
sucDsuccinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (291 aa)
SYN_02536Isopropylmalate/homocitrate/citramalate synthases. (629 aa)
SYN_02966Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (803 aa)
SYN_03161Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. (227 aa)
SYN_031622-oxoacid ferredoxin oxidoreductase, alpha subunit. (344 aa)
SYN_031632-oxoacid ferredoxin oxidoreductase, beta subunit. (274 aa)
SYN_03227succinyl-CoA synthetase beta chain. (380 aa)
Your Current Organism:
Syntrophus aciditrophicus
NCBI taxonomy Id: 56780
Other names: S. aciditrophicus SB, Syntrophus aciditrophicus SB, Syntrophus aciditrophicus str. SB, Syntrophus aciditrophicus strain SB
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