STRINGSTRING
bamD bamD murJ murJ SYN_00105 SYN_00105 SYN_00106 SYN_00106 SYN_00133 SYN_00133 SYN_00134 SYN_00134 SYN_00191 SYN_00191 SYN_00192 SYN_00192 SYN_00193 SYN_00193 SYN_00194 SYN_00194 SYN_00195 SYN_00195 SYN_00196 SYN_00196 SYN_00197 SYN_00197 SYN_00304 SYN_00304 ddl ddl SYN_00413 SYN_00413 SYN_00414 SYN_00414 SYN_00415 SYN_00415 SYN_00436 SYN_00436 ftsZ ftsZ SYN_00467 SYN_00467 SYN_00471 SYN_00471 SYN_00516 SYN_00516 SYN_00541 SYN_00541 mrdB mrdB SYN_00551 SYN_00551 SYN_00552 SYN_00552 SYN_00553 SYN_00553 SYN_00554 SYN_00554 SYN_00555 SYN_00555 SYN_00571 SYN_00571 SYN_00572 SYN_00572 lpxC lpxC SYN_00884 SYN_00884 SYN_00903 SYN_00903 SYN_00915 SYN_00915 SYN_00921 SYN_00921 lolD lolD SYN_00923 SYN_00923 SYN_00927 SYN_00927 SYN_00931 SYN_00931 SYN_00940 SYN_00940 SYN_00946 SYN_00946 SYN_00947 SYN_00947 SYN_00948 SYN_00948 SYN_00949 SYN_00949 kdsA kdsA SYN_00979 SYN_00979 SYN_00980 SYN_00980 SYN_00999 SYN_00999 pcm pcm SYN_01001 SYN_01001 SYN_01066 SYN_01066 SYN_01067 SYN_01067 SYN_01366 SYN_01366 SYN_01367 SYN_01367 mtgA mtgA SYN_01408 SYN_01408 SYN_01413 SYN_01413 SYN_01414 SYN_01414 SYN_01415 SYN_01415 SYN_01416 SYN_01416 SYN_01417 SYN_01417 SYN_01418 SYN_01418 SYN_01419 SYN_01419 lspA lspA SYN_01476 SYN_01476 SYN_01478 SYN_01478 SYN_01482 SYN_01482 ddl-2 ddl-2 SYN_01484 SYN_01484 SYN_01486 SYN_01486 lpxK lpxK lpxB lpxB lpxA lpxA lpxD lpxD SYN_01569 SYN_01569 lptD lptD SYN_01703 SYN_01703 SYN_01726 SYN_01726 SYN_01734 SYN_01734 mltG mltG mraZ mraZ rsmH rsmH ftsL ftsL SYN_01739 SYN_01739 murE murE murF murF mraY mraY murD murD SYN_01745 SYN_01745 murG murG murC murC murB murB SYN_01766 SYN_01766 murA murA SYN_01799 SYN_01799 SYN_01923 SYN_01923 SYN_01931 SYN_01931 rlpA rlpA SYN_01998 SYN_01998 SYN_02024 SYN_02024 kdsB kdsB SYN_02082 SYN_02082 SYN_02145 SYN_02145 SYN_02260 SYN_02260 SYN_02375 SYN_02375 SYN_02433 SYN_02433 SYN_02449 SYN_02449 SYN_02487 SYN_02487 SYN_02494 SYN_02494 SYN_02713 SYN_02713 SYN_02714 SYN_02714 SYN_02783 SYN_02783 lnt lnt SYN_02791 SYN_02791 SYN_02849 SYN_02849 SYN_02855 SYN_02855 SYN_02892 SYN_02892 SYN_02967 SYN_02967 SYN_03045 SYN_03045 SYN_03047 SYN_03047 SYN_03056 SYN_03056 SYN_03067 SYN_03067 ftsA ftsA SYN_03182 SYN_03182 SYN_03195 SYN_03195 SYN_03198 SYN_03198 SYN_03409 SYN_03409 SYN_03778 SYN_03778 SYN_03827 SYN_03827
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bamDLipoprotein, ComL family; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (239 aa)
murJVirulence factor protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (527 aa)
SYN_00105Hypothetical cytosolic protein; Belongs to the UPF0235 family. (118 aa)
SYN_00106Hypothetical membrane protein. (137 aa)
SYN_00133Lipid A biosynthesis lauroyl acyltransferase. (292 aa)
SYN_00134Tetratricopeptide repeat family protein. (322 aa)
SYN_00191Hypothetical membrane protein. (331 aa)
SYN_00192Tetratricopeptide repeat family protein. (563 aa)
SYN_00193Polysaccharide deacetylase. (334 aa)
SYN_00194Periplasmic protease; Belongs to the peptidase S41A family. (435 aa)
SYN_00195Hypothetical cytosolic protein. (270 aa)
SYN_00196Uncharacterized protein with SCP/PR1 domain. (244 aa)
SYN_00197rmuC family protein. (421 aa)
SYN_00304Multimodular transpeptidase-transglycosylase. (674 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (355 aa)
SYN_00413Hypothetical exported protein. (264 aa)
SYN_00414Permease. (394 aa)
SYN_00415Permease. (359 aa)
SYN_00436Fe-S oxidoreductase. (563 aa)
ftsZCell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (384 aa)
SYN_00467Hypothetical cytosolic protein. (172 aa)
SYN_00471Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. (336 aa)
SYN_00516Hypothetical membrane protein. (290 aa)
SYN_00541SAM-dependent methyltransferase. (257 aa)
mrdBRod shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (369 aa)
SYN_00551Cell elongation specific D,D-transpeptidase. (630 aa)
SYN_00552Hypothetical membrane protein. (173 aa)
SYN_00553Rod shape-determining protein; Involved in formation and maintenance of cell shape. (277 aa)
SYN_00554Rod shape-determining protein. (345 aa)
SYN_00555Peptidyl-prolyl cis-trans isomerase. (533 aa)
SYN_00571Alanine racemase, N-terminal domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (232 aa)
SYN_00572Putative inhibitor of septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (219 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (315 aa)
SYN_00884Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (237 aa)
SYN_00903N-acetylmuramoyl-L-alanine amidase. (233 aa)
SYN_00915Membrane metalloprotease. (366 aa)
SYN_00921Outer membrane protein. (885 aa)
lolDLipoprotein releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (223 aa)
SYN_00923Lipoprotein releasing system, permease component. (425 aa)
SYN_00927Hypothetical membrane protein. (300 aa)
SYN_00931Integrin-like repeat protein. (572 aa)
SYN_00940Peptidoglycan-specific endopeptidase, M23 family. (453 aa)
SYN_00946ABC transporter ATP-binding protein. (240 aa)
SYN_00947Organic solvent tolerance protein. (197 aa)
SYN_00948Hypothetical membrane protein. (198 aa)
SYN_009493-deoxy-manno-octulosonate-8-phosphatase. (183 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (292 aa)
SYN_00979Alanine dehydrogenase; Belongs to the AlaDH/PNT family. (409 aa)
SYN_00980Hypothetical cytosolic protein. (78 aa)
SYN_00999Lipoprotein. (322 aa)
pcmprotein-L-isoaspartate o-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (218 aa)
SYN_01001Hypothetical cytosolic protein. (132 aa)
SYN_01066Deoxyguanosinetriphosphate triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (400 aa)
SYN_01067Phosphoribosylaminoimidazole carboxylase ATPase subunit. (111 aa)
SYN_01366Calcineurin-like phosphoesterase. (266 aa)
SYN_01367Hypothetical membrane protein. (226 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (313 aa)
SYN_01408Cell wall-associated hydrolase. (372 aa)
SYN_01413Soluble lytic murein transglycosylase. (203 aa)
SYN_01414Tetratricopeptide repeat family protein. (277 aa)
SYN_01415Hydrolase; HAD superfamily. (198 aa)
SYN_01416Hypothetical cytosolic protein. (78 aa)
SYN_01417Hypothetical membrane protein. (110 aa)
SYN_01418lysM domain protein. (557 aa)
SYN_01419Putative tRNA (5-methylaminomethyl-2-thiouridylate) -methyltransferase / fibronectin/fibrinogen-binding protein. (333 aa)
lspALipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (161 aa)
SYN_01476Bacterial regulatory protein, LuxR family. (302 aa)
SYN_01478Uncharacterized BCR, YitT family protein. (291 aa)
SYN_01482Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (661 aa)
ddl-2D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (352 aa)
SYN_01484Hypothetical cytosolic protein. (131 aa)
SYN_01486Cell wall-associated hydrolase. (275 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (374 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (383 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (258 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (363 aa)
SYN_01569Outer membrane protein. (176 aa)
lptDOrganic solvent tolerance protein; Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane; Belongs to the LptD family. (768 aa)
SYN_01703Hypothetical cytosolic protein. (153 aa)
SYN_01726Hypothetical cytosolic protein. (93 aa)
SYN_017344-amino-4-deoxychorismate lyase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (150 aa)
mltG4-amino-4-deoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (358 aa)
mraZCell division protein; Belongs to the MraZ family. (148 aa)
rsmHS-adenosyl-methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (315 aa)
ftsLHypothetical membrane protein; Essential cell division protein; Belongs to the FtsL family. (115 aa)
SYN_01739Division specific D,D-transpeptidase / cell division protein. (667 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (509 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (475 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (359 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (453 aa)
SYN_01745Cell division protein; Belongs to the SEDS family. (390 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (361 aa)
murCUDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (480 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (312 aa)
SYN_01766Lysine decarboxylase family; Belongs to the LOG family. (219 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa)
SYN_01799Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. (282 aa)
SYN_01923Nif3-related protein. (252 aa)
SYN_01931ATPase involved in pili bigenesis. (1185 aa)
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (150 aa)
SYN_01998Multimodular transpeptidase-transglycosylase. (687 aa)
SYN_02024Carboxy-terminal processing protease precursor; Belongs to the peptidase S41A family. (698 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (248 aa)
SYN_02082Membrane carboxypeptidase; Penicillin-binding protein. (1052 aa)
SYN_02145N-acetylmuramoyl-L-alanine amidase. (725 aa)
SYN_02260D-alanyl-D-alanine serine-type carboxypeptidase; Belongs to the peptidase S11 family. (310 aa)
SYN_02375Hypothetical membrane protein. (190 aa)
SYN_02433Hypothetical lipoprotein. (260 aa)
SYN_02449Hypothetical membrane protein. (344 aa)
SYN_02487Peptidyl-prolyl cis-trans isomerase. (322 aa)
SYN_02494Hypothetical cytosolic protein. (113 aa)
SYN_02713Response regulator containing sigma 54 interaction domain. (457 aa)
SYN_02714Signal transduction histidine kinase involved in nitrogen metabolism regulation. (740 aa)
SYN_02783Soluble lytic murein transglycosylase. (217 aa)
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (514 aa)
SYN_02791Membrane-bound lytic murein transglycosylase D precursor. (654 aa)
SYN_02849Tetratricopeptide repeat domain. (340 aa)
SYN_02855Hypothetical exported protein. (510 aa)
SYN_02892Zn-dependent hydrolase. (270 aa)
SYN_02967Zn binding protein. (240 aa)
SYN_03045Cell division protein; Essential cell division protein. (281 aa)
SYN_03047Hypothetical cytosolic protein. (153 aa)
SYN_03056Hypothetical cytosolic protein. (311 aa)
SYN_03067Hypothetical membrane protein. (294 aa)
ftsACell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (409 aa)
SYN_03182Hypothetical membrane protein. (82 aa)
SYN_03195Zinc metalloprotease. (461 aa)
SYN_03198Signal peptide peptidase. (309 aa)
SYN_03409Hypothetical membrane protein. (65 aa)
SYN_03778Septum formation initiator; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (91 aa)
SYN_03827Hypothetical cytosolic protein. (100 aa)
Your Current Organism:
Syntrophus aciditrophicus
NCBI taxonomy Id: 56780
Other names: S. aciditrophicus SB, Syntrophus aciditrophicus SB, Syntrophus aciditrophicus str. SB, Syntrophus aciditrophicus strain SB
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