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SYN_00123 SYN_00123 SYN_00124 SYN_00124 SYN_00168 SYN_00168 dapF dapF argC argC SYN_00570 SYN_00570 dapF-2 dapF-2 hisA hisA SYN_00890 SYN_00890 SYN_00908 SYN_00908 asd asd argJ argJ SYN_01164 SYN_01164 SYN_01299 SYN_01299 SYN_01300 SYN_01300 proB proB SYN_01390 SYN_01390 hisF hisF SYN_01455 SYN_01455 hisC hisC SYN_01609 SYN_01609 hisH hisH hisF-2 hisF-2 hisD hisD SYN_01933 SYN_01933 aroC aroC aroK aroK aroA aroA aroE aroE aroD aroD aroB aroB SYN_01940 SYN_01940 trpA trpA trpB trpB trpF trpF trpC trpC trpD trpD SYN_01946 SYN_01946 trpE trpE proA proA SYN_02122 SYN_02122 argB argB argD argD argF argF argG argG argH argH SYN_02159 SYN_02159 lysA lysA dapA dapA dapB dapB SYN_02164 SYN_02164 proC proC SYN_02256 SYN_02256 trpF-2 trpF-2 trpD-2 trpD-2 SYN_02591 SYN_02591 trpF-3 trpF-3 SYN_02678 SYN_02678 SYN_02781 SYN_02781 SYN_02795 SYN_02795 SYN_02937 SYN_02937 hisB hisB SYN_03109 SYN_03109 hisI hisI SYN_03154 SYN_03154 SYN_03155 SYN_03155 SYN_03220 SYN_03220 SYN_03698 SYN_03698
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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SYN_00123D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (527 aa)
SYN_00124Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (351 aa)
SYN_00168Aminotransferase, class I and II. (388 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (277 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (362 aa)
SYN_00570Acetylornithine aminotransferase / Succinyldiaminopimelate aminotransferase; Bifunctional; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (401 aa)
dapF-2Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (295 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (242 aa)
SYN_00890Homoserine dehydrogenase. (437 aa)
SYN_00908Aspartate aminotransferase. (400 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa)
argJGlutamate N-acetyltransferase / amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (400 aa)
SYN_01164Histidinol-phosphate aminotransferase. (336 aa)
SYN_01299Prephenate dehydratase. (354 aa)
SYN_013003-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase. (279 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (385 aa)
SYN_01390Argininosuccinate synthase. (299 aa)
hisFImidazole glycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (254 aa)
SYN_01455Tyrosine phenol-lyase. (481 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (361 aa)
SYN_01609Modulator of glutathione-dependent potassium efflux system. (208 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
hisF-2Imidazole glycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (259 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa)
SYN_01933Prephenate dehydrogenase. (270 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (354 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (195 aa)
aroA3-phosphoshikimate-1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (446 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (292 aa)
aroD3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (372 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (364 aa)
SYN_01940Phospho-2-dehydro-3-deoxyheptanoate aldolase. (372 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa)
trpBTrytophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (230 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (276 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (346 aa)
SYN_01946Anthranilate synthase component II. (208 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (494 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (418 aa)
SYN_02122Threonine synthase. (483 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (296 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (396 aa)
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (302 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (401 aa)
argHArgininosuccinate lyase. (472 aa)
SYN_02159Hypothetical membrane protein. (157 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (427 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (268 aa)
SYN_02164Hypothetical membrane protein. (93 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (272 aa)
SYN_02256Phospho-2-dehydro-3-deoxyheptonate aldolase. (461 aa)
trpF-2N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (230 aa)
trpD-2Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (448 aa)
SYN_02591Indole-3-glycerol phosphate synthase. (245 aa)
trpF-3N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (249 aa)
SYN_02678Asparagine synthetase (glutamine-hydrolyzing). (645 aa)
SYN_02781Aspartokinase; Belongs to the aspartokinase family. (406 aa)
SYN_02795Succinyl-diaminopimelate desuccinylase. (417 aa)
SYN_02937Aspartate aminotransferase. (395 aa)
hisBImidazoleglycerol-phosphate dehydratase. (197 aa)
SYN_03109ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). (237 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (123 aa)
SYN_03154Branched-chain amino acid aminotransferase. (228 aa)
SYN_03155Branched-chain amino acid aminotransferase. (125 aa)
SYN_03220Hypothetical cytosolic protein. (41 aa)
SYN_03698ATP phosphoribosyltransferase. (66 aa)
Your Current Organism:
Syntrophus aciditrophicus
NCBI taxonomy Id: 56780
Other names: S. aciditrophicus SB, Syntrophus aciditrophicus SB, Syntrophus aciditrophicus str. SB, Syntrophus aciditrophicus strain SB
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