STRINGSTRING
adk adk SYN_02163 SYN_02163 argB argB SYN_02118 SYN_02118 SYN_02093 SYN_02093 SYN_02092 SYN_02092 SYN_01948 SYN_01948 aroK aroK SYN_01919 SYN_01919 SYN_01808 SYN_01808 SYN_01800 SYN_01800 SYN_01729 SYN_01729 SYN_01701 SYN_01701 SYN_01575 SYN_01575 SYN_01573 SYN_01573 lpxK lpxK SYN_01522 SYN_01522 SYN_01521 SYN_01521 SYN_01465 SYN_01465 SYN_01443 SYN_01443 SYN_01420 SYN_01420 pgk pgk proB proB gmk gmk SYN_01231 SYN_01231 SYN_01213 SYN_01213 buk buk SYN_01204 SYN_01204 SYN_01135 SYN_01135 SYN_01094 SYN_01094 SYN_01090 SYN_01090 SYN_00963 SYN_00963 SYN_00942 SYN_00942 pyrH pyrH pfkA pfkA SYN_00886 SYN_00886 SYN_00869 SYN_00869 SYN_00780 SYN_00780 SYN_00568 SYN_00568 SYN_00566 SYN_00566 SYN_00043 SYN_00043 SYN_00061 SYN_00061 SYN_00127 SYN_00127 SYN_00137 SYN_00137 SYN_00174 SYN_00174 SYN_00226 SYN_00226 SYN_00227 SYN_00227 SYN_00293 SYN_00293 thiM thiM SYN_00394 SYN_00394 SYN_00431 SYN_00431 SYN_00462 SYN_00462 tmk tmk cmk cmk SYN_03131 SYN_03131 buk-2 buk-2 ispE ispE SYN_02966 SYN_02966 pfkA-2 pfkA-2 SYN_02952 SYN_02952 glk glk coaX coaX coaE coaE SYN_02874 SYN_02874 nadK nadK SYN_02845 SYN_02845 SYN_02844 SYN_02844 SYN_02825 SYN_02825 SYN_02781 SYN_02781 SYN_02780 SYN_02780 prs prs SYN_02721 SYN_02721 SYN_02714 SYN_02714 SYN_02581 SYN_02581 SYN_02576 SYN_02576 adk-2 adk-2 SYN_02531 SYN_02531 SYN_02496 SYN_02496 SYN_02383 SYN_02383 SYN_02357 SYN_02357 SYN_02353 SYN_02353 SYN_02215 SYN_02215 SYN_02213 SYN_02213
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
adkAdenylate kinase / nucleoside-diphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (235 aa)
SYN_021637, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). (176 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (296 aa)
SYN_02118Selenide water dikinase. (305 aa)
SYN_02093Hypothetical cytosolic protein. (230 aa)
SYN_02092Fog:ggdef domain membrane protein. (462 aa)
SYN_01948Riboflavin kinase / FMN adenylyltransferase; Bifunctional; Belongs to the ribF family. (326 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (195 aa)
SYN_01919Sigma-54-dependent transcriptional activator. (522 aa)
SYN_01808Signal transduction histidine kinase. (503 aa)
SYN_01800Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (333 aa)
SYN_01729Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (594 aa)
SYN_01701Signal transduction histidine kinase. (506 aa)
SYN_01575relA / spoT related protein. (407 aa)
SYN_01573Hypothetical cytosolic protein. (252 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (374 aa)
SYN_01522Thiamin pyrophosphokinase. (235 aa)
SYN_01521Phosphomethylpyrimidine kinase / hydroxymethylpyrimidine kinase; Bifunctional. (293 aa)
SYN_01465Signal transduction histidine kinase. (415 aa)
SYN_01443Hypothetical cytosolic protein. (274 aa)
SYN_01420Hypothetical cytosolic protein. (509 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (423 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (385 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa)
SYN_01231Cytidylate kinase. (231 aa)
SYN_01213Carbamate kinase; Belongs to the carbamate kinase family. (323 aa)
bukButyrate kinase; Belongs to the acetokinase family. (360 aa)
SYN_01204Chain length determinant protein, Wzz-like protein. (525 aa)
SYN_01135Hypothetical cytosolic protein. (232 aa)
SYN_01094Signal transduction histidine kinase. (614 aa)
SYN_01090Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains. (535 aa)
SYN_00963Chemotaxis protein. (735 aa)
SYN_00942Serine kinase of the HPr protein, regulates carbohydrate metabolism. (300 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (243 aa)
pfkAPyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (463 aa)
SYN_008866-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (404 aa)
SYN_00869Glycerate dehydrogenase / hydroxypyruvate reductase; Bifunctional. (438 aa)
SYN_00780Chain length determinant protein, Wzz-like protein. (514 aa)
SYN_00568Signal transduction histidine kinase with reciever domain protein. (649 aa)
SYN_00566Sensory transduction protein with PAS domain. (531 aa)
SYN_00043Gluconate kinase. (530 aa)
SYN_00061Phosphate regulon sensor protein. (583 aa)
SYN_00127Response regulator receiver domain. (190 aa)
SYN_00137Hypothetical cytosolic protein; Belongs to the UPF0434 family. (67 aa)
SYN_00174Signal transduction histidine kinase with receiver domain. (615 aa)
SYN_00226Signal transduction histidine kinase. (683 aa)
SYN_00227Hypothetical cytosolic protein. (104 aa)
SYN_00293Transcriptional regulator-like protein. (68 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (270 aa)
SYN_00394Hypothetical cytosolic protein. (121 aa)
SYN_00431Chemotaxis protein. (786 aa)
SYN_00462Hypothetical cytosolic protein. (72 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (219 aa)
cmkCytidylate kinase. (256 aa)
SYN_03131Phosphatidylethanolamine-binding protein. (185 aa)
buk-2Butyrate kinase; Belongs to the acetokinase family. (362 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (279 aa)
SYN_02966Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (803 aa)
pfkA-2Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. (434 aa)
SYN_02952Pyruvate kinase; Belongs to the pyruvate kinase family. (475 aa)
glkGlucokinase; Belongs to the bacterial glucokinase family. (337 aa)
coaXBvg accessory factor; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (254 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (235 aa)
SYN_02874Ribokinase. (314 aa)
nadKATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (295 aa)
SYN_02845Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB. (187 aa)
SYN_02844Pts system fructose IIA component. (155 aa)
SYN_02825Hypothetical cytosolic protein. (262 aa)
SYN_02781Aspartokinase; Belongs to the aspartokinase family. (406 aa)
SYN_02780ATP/GTP hydrolase. (157 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (313 aa)
SYN_02721HD domain / HAMP domain protein. (484 aa)
SYN_02714Signal transduction histidine kinase involved in nitrogen metabolism regulation. (740 aa)
SYN_02581Signal transduction histidine kinase. (437 aa)
SYN_02576Signal transduction histidine kinase. (725 aa)
adk-2Adenylate kinase / nucleoside-diphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (241 aa)
SYN_02531Signal transduction histidine kinase. (576 aa)
SYN_02496Cytidylate kinase. (218 aa)
SYN_02383Phosphoenolpyruvate synthase. (907 aa)
SYN_02357Anti-sigma regulatory factor; Ser/Thr protein kinase. (137 aa)
SYN_02353Putative diacylglycerolkinase. (118 aa)
SYN_02215Signal transduction histidine kinase. (593 aa)
SYN_02213Signal transduction histidine kinase. (718 aa)
Your Current Organism:
Syntrophus aciditrophicus
NCBI taxonomy Id: 56780
Other names: S. aciditrophicus SB, Syntrophus aciditrophicus SB, Syntrophus aciditrophicus str. SB, Syntrophus aciditrophicus strain SB
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