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| | SYN_00434 | Chemotaxis protein methyltransferase. (523 aa) |
| | cheB1 | Protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (358 aa) |
| | moaA | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (345 aa) |
| | SYN_00359 | DNA polymerase V subunit; Represses a number of genes involved in the response to DNA damage (SOS response). (195 aa) |
| | SYN_00323 | Membrane endopeptidase, M50 family; Belongs to the peptidase M50B family. (377 aa) |
| | gatB2 | aspartyl/glutamyl-tRNA(asn/gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (476 aa) |
| | gatA | aspartyl/glutamyl-tRNA(asn/gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (485 aa) |
| | gatC | aspartyl/glutamyl-tRNA(asn/gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa) |
| | SYN_00304 | Multimodular transpeptidase-transglycosylase. (674 aa) |
| | htpX | Endopeptidase; Belongs to the peptidase M48B family. (276 aa) |
| | SYN_00289 | Molybdopterin-guanine dinucleotide biosynthesis protein B. (169 aa) |
| | SYN_00288 | Uncharacterized protein involved in formate dehydrogenase formation; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (276 aa) |
| | SYN_00279 | Radical SAM superfamily protein. (477 aa) |
| | SYN_00274 | Fatty acid binding protein. (754 aa) |
| | SYN_00272 | Molybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (427 aa) |
| | SYN_00267 | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (676 aa) |
| | SYN_00266 | Molybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (410 aa) |
| | rpsI | SSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (134 aa) |
| | rplM | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa) |
| | SYN_00226 | Signal transduction histidine kinase. (683 aa) |
| | SYN_00194 | Periplasmic protease; Belongs to the peptidase S41A family. (435 aa) |
| | SYN_00184 | Truncated lysyl-tRNA synthetase; Class II. (332 aa) |
| | efp | Protein translation Elongation Factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (187 aa) |
| | SYN_00174 | Signal transduction histidine kinase with receiver domain. (615 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (448 aa) |
| | rpmG | LSU ribosomal protein L33P; Belongs to the bacterial ribosomal protein bL33 family. (49 aa) |
| | rplK | LSU ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (144 aa) |
| | rplA | LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (232 aa) |
| | rplJ | LSU ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (174 aa) |
| | rplL | LSU ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (140 aa) |
| | SYN_00061 | Phosphate regulon sensor protein. (583 aa) |
| | SYN_00049 | acetyl-CoA synthetase beta subunit. (701 aa) |
| | SYN_00042 | Sir2 family protein. (257 aa) |
| | SYN_00033 | Hypothetical membrane protein. (220 aa) |
| | SYN_00020 | Hypothetical cytosolic protein. (333 aa) |
| | htpX-2 | Endopeptidase htpX; Belongs to the peptidase M48B family. (284 aa) |
| | rpsH | SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (133 aa) |
| | rpsZ | SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa) |
| | rplE | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa) |
| | rplX | LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (106 aa) |
| | SYN_03311 | Ribosomal protein S12. (44 aa) |
| | rplN | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (140 aa) |
| | rpsQ | SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (85 aa) |
| | rpsG | SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (158 aa) |
| | rpsL | SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. (62 aa) |
| | SYN_03230 | Zn-dependent protease with chaperone function. (453 aa) |
| | SYN_03201 | DNA repair protein; Belongs to the UPF0758 family. (308 aa) |
| | SYN_03198 | Signal peptide peptidase. (309 aa) |
| | SYN_03197 | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (586 aa) |
| | SYN_03195 | Zinc metalloprotease. (461 aa) |
| | SYN_03164 | Hypothetical cytosolic protein. (783 aa) |
| | SYN_03148 | Xaa-pro aminopeptidase. (411 aa) |
| | tsf | Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (201 aa) |
| | SYN_03142 | Peptidase, M16 family; Belongs to the peptidase M16 family. (522 aa) |
| | SYN_03060 | Hypothetical membrane protein. (237 aa) |
| | cysS-2 | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (550 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (428 aa) |
| | SYN_02963 | Aminopeptidase. (401 aa) |
| | SYN_02931 | Hypothetical cytosolic protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (175 aa) |
| | SYN_02930 | Protein translation elongation factor G. (691 aa) |
| | moaC | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (174 aa) |
| | SYN_02909 | DNA helicase. (1606 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (887 aa) |
| | SYN_02878 | acetyl-CoA synthetase / acetyltransferase (GNAT) family protein. (918 aa) |
| | SYN_02857 | tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (341 aa) |
| | SYN_02847 | Acetyltransferase GNAT family. (175 aa) |
| | SYN_02825 | Hypothetical cytosolic protein. (262 aa) |
| | SYN_02796 | Predicted Zn-dependent peptidase. (479 aa) |
| | prfB | Bacterial peptide Chain Release Factor 2 (RF-2); Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (279 aa) |
| | lnt | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (514 aa) |
| | lon-2 | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (812 aa) |
| | clpP | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (194 aa) |
| | acpS | Holo- synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (128 aa) |
| | ftsH | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (611 aa) |
| | pth | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (196 aa) |
| | rplY | LSU ribosomal protein L25P; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (200 aa) |
| | SYN_02766 | Protease I. (189 aa) |
| | SYN_02757 | Hypothetical cytosolic protein. (139 aa) |
| | SYN_02756 | ATP-dependent protease La. (683 aa) |
| | SYN_02748 | Hypothetical cytosolic protein. (1165 aa) |
| | SYN_02721 | HD domain / HAMP domain protein. (484 aa) |
| | SYN_02714 | Signal transduction histidine kinase involved in nitrogen metabolism regulation. (740 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (312 aa) |
| | SYN_02689 | UDP-N-acetylglucosamine 4,6-dehydratase / UDP-4-dehydro-6-deoxy-2-acetamido-D-glucose 4-reductase; Bifunctional. (644 aa) |
| | SYN_02684 | Hypothetical cytosolic protein. (735 aa) |
| | SYN_02676 | Hypothetical cytosolic protein. (666 aa) |
| | SYN_02670 | UDP-N-acetylglucosamine 4,6-dehydratase / UDP-D-quinovosamine 4-dehydrogenase; Bifunctional. (637 aa) |
| | SYN_02667 | alpha-D-QuiNAc alpha-1,3-galactosyltransferase. (376 aa) |
| | SYN_02665 | Glycosyltransferase. (302 aa) |
| | SYN_02660 | Glycosyltransferase. (363 aa) |
| | SYN_02612 | Hypothetical cytosolic protein. (270 aa) |
| | SYN_02609 | acetyl-CoA synthetase beta subunit. (700 aa) |
| | SYN_02607 | acetyl-CoA synthetase / acetyltransferase (GNAT) family protein. (899 aa) |
| | gatB1 | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (478 aa) |
| | SYN_02603 | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A. (453 aa) |
| | aspS1 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (723 aa) |
| | SYN_02581 | Signal transduction histidine kinase. (437 aa) |
| | SYN_02576 | Signal transduction histidine kinase. (725 aa) |
| | gltX1 | Glutamyl glutaminyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (472 aa) |
| | SYN_02546 | Outer membrane protein. (742 aa) |
| | aspS2 | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (591 aa) |
| | hisS | histidyl-tRNA synthetase. (426 aa) |
| | SYN_02531 | Signal transduction histidine kinase. (576 aa) |
| | SYN_02461 | Deoxyhypusine synthase; Belongs to the deoxyhypusine synthase family. (391 aa) |
| | SYN_02408 | Radical SAM superfamily protein. (396 aa) |
| | SYN_02389 | Dolichyl-phosphate-mannose--protein mannosyltransferase. (528 aa) |
| | aat | leu/phe-tRNA-protein transferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl- tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. (239 aa) |
| | clpS | ATP-dependent Clp protease adaptor protein; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. (107 aa) |
| | rpsT | SSU ribosomal protein S20; Binds directly to 16S ribosomal RNA. (89 aa) |
| | leuS | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (862 aa) |
| | rpmF | LSU ribosomal protein L32P; Belongs to the bacterial ribosomal protein bL32 family. (61 aa) |
| | SYN_02302 | Mu-like prophage Flumu F protein. (401 aa) |
| | SYN_02300 | Mu-like prophage Flumu I protein. (353 aa) |
| | prmA | Ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (319 aa) |
| | ftsH-2 | Cell division protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. (736 aa) |
| | SYN_02260 | D-alanyl-D-alanine serine-type carboxypeptidase; Belongs to the peptidase S11 family. (310 aa) |
| | SYN_02229 | DNA damage inducible protein. (89 aa) |
| | SYN_02215 | Signal transduction histidine kinase. (593 aa) |
| | SYN_02213 | Signal transduction histidine kinase. (718 aa) |
| | SYN_02209 | Metal-dependent hydrolase. (247 aa) |
| | SYN_02199 | Zn-dependent protease with chaperone function. (287 aa) |
| | SYN_02193 | Hypothetical cytosolic protein. (380 aa) |
| | SYN_02191 | Selenocysteine-specific protein translation Elongation Factor. (636 aa) |
| | smpB | ssrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (158 aa) |
| | lepA | Membrane GTPase; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (598 aa) |
| | SYN_02180 | Membrane protease subunit, stomatin/prohibitin -like protein. (249 aa) |
| | SYN_02179 | Membrane-bound serine protease. (440 aa) |
| | pepA | Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (526 aa) |
| | hslV | ATP-dependent endopeptidase hsl proteolytic subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. (212 aa) |
| | SYN_02148 | Molybdopterin biosynthesis MoeA protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (403 aa) |
| | glnS | glutaminyl-tRNA synthetase. (562 aa) |
| | SYN_02112 | acetyl-CoA synthetase beta subunit. (697 aa) |
| | SYN_02092 | Fog:ggdef domain membrane protein. (462 aa) |
| | SYN_02061 | Zinc metalloprotease. (227 aa) |
| | SYN_02039 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (171 aa) |
| | SYN_02034 | Hypothetical cytosolic protein. (150 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (878 aa) |
| | SYN_02024 | Carboxy-terminal processing protease precursor; Belongs to the peptidase S41A family. (698 aa) |
| | SYN_02023 | Endopeptidase. (386 aa) |
| | SYN_01998 | Multimodular transpeptidase-transglycosylase. (687 aa) |
| | SYN_01978 | ABC transporter ATP-binding protein. (561 aa) |
| | moaA-2 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa) |
| | SYN_01958 | Molybdopterin converting factor, large subunit. (125 aa) |
| | SYN_01949 | acyl-CoA synthetase; NDP forming. (727 aa) |
| | SYN_01919 | Sigma-54-dependent transcriptional activator. (522 aa) |
| | fusA2 | Protein translation Elongation Factor G (EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase fami [...] (677 aa) |
| | SYN_01888 | ATPase components of ABC transporters with duplicated ATPase domains. (501 aa) |
| | SYN_01872 | Type IV secretory protease. (161 aa) |
| | SYN_01833 | hesA/moeB/thiF type protein. (1158 aa) |
| | SYN_01823 | Hypothetical cytosolic protein. (475 aa) |
| | SYN_01808 | Signal transduction histidine kinase. (503 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (189 aa) |
| | selA | L-seryl-tRNA(sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (474 aa) |
| | rpmE | LSU ribosomal protein L31P; Binds the 23S rRNA. (71 aa) |
| | prfA | Bacterial peptide chain release factor 1 (rf-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (357 aa) |
| | prmC | Peptide release factor-glutamine N5-methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (316 aa) |
| | nusA | Transcription elongation factor; Participates in both transcription termination and antitermination. (420 aa) |
| | infB | Bacterial protein translation Initiation Factor 2 (IF-2); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (924 aa) |
| | rpsO | SSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (88 aa) |
| | SYN_01769 | Xaa-pro dipeptidase. (377 aa) |
| | rpsU | SSU ribosomal protein S21P; Belongs to the bacterial ribosomal protein bS21 family. (63 aa) |
| | hflX | GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. (555 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (804 aa) |
| | pheS | phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (338 aa) |
| | rplT | LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (119 aa) |
| | rpmI | LSU ribosomal protein L35P; Belongs to the bacterial ribosomal protein bL35 family. (65 aa) |
| | infC | Translation initiation factor 3 (IF-3); IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (181 aa) |
| | thrS | threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (645 aa) |
| | SYN_01706 | Endopeptidase; Belongs to the peptidase S1C family. (494 aa) |
| | SYN_01701 | Signal transduction histidine kinase. (506 aa) |
| | fdhD-3 | Formate dehydrogenase activity protein; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family. (233 aa) |
| | fdhD-2 | Formate dehydrogenase activity protein; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family. (273 aa) |
| | SYN_01668 | Iron-sulfur cluster assembly/repair protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family. (340 aa) |
| | SYN_01652 | Xaa-pro aminopeptidase. (391 aa) |
| | rplQ | LSU ribosomal protein L17P. (125 aa) |
| | rpsD | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (209 aa) |
| | rpsK | SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (130 aa) |
| | rpsM | SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (122 aa) |
| | infA | Bacterial protein translation Initiation Factor 1 (IF-1); One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | map | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (249 aa) |
| | rplO | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (147 aa) |
| | rpmD | LSU ribosomal protein L30P. (64 aa) |
| | rpsE | SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (164 aa) |
| | rplR | LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (121 aa) |
| | rplF | LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (179 aa) |
| | fusA1 | Protein translation elongation factor G (EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase fami [...] (695 aa) |
| | SYN_01569 | Outer membrane protein. (176 aa) |
| | glyS | glycyl-tRNA synthetase beta chain. (690 aa) |
| | glyQ | glycyl-tRNA synthetase alpha chain. (292 aa) |
| | SYN_01527 | Signal peptidase I; Belongs to the peptidase S26 family. (203 aa) |
| | SYN_01490 | Flp pilus assembly protein, protease. (180 aa) |
| | SYN_01486 | Cell wall-associated hydrolase. (275 aa) |
| | SYN_01465 | Signal transduction histidine kinase. (415 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (933 aa) |
| | lspA | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (161 aa) |
| | lgt | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (286 aa) |
| | SYN_01408 | Cell wall-associated hydrolase. (372 aa) |
| | gltX2 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (486 aa) |
| | rplU | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (105 aa) |
| | rpmA | LSU ribosomal protein L27P; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | SYN_01313 | Hypothetical cytosolic protein; Belongs to the SOS response-associated peptidase family. (207 aa) |
| | SYN_01286 | Zinc metalloprotease. (190 aa) |
| | rimO | tRNA 2-methylthioadenine synthetase -like protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (453 aa) |
| | msrB | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (362 aa) |
| | fdhD | Protein required for formate dehydrogenase activity; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (253 aa) |
| | SYN_01156 | ATP-dependent protease La. (824 aa) |
| | SYN_01107 | Glycosyltransferase. (361 aa) |
| | SYN_01103 | Glycosyltransferase. (333 aa) |
| | SYN_01097 | Hypothetical membrane protein. (527 aa) |
| | SYN_01094 | Signal transduction histidine kinase. (614 aa) |
| | SYN_01090 | Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains. (535 aa) |
| | SYN_01084 | Muramoyltetrapeptide carboxypeptidase. (288 aa) |
| | rpsB | Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (277 aa) |
| | SYN_01026 | Rhomboid family protein. (289 aa) |
| | SYN_01020 | Sir2 family of NAD+-dependent deacetylase. (271 aa) |
| | SYN_01004 | Protein involved in biosynthesis of molybdopterin. (116 aa) |
| | pcm | protein-L-isoaspartate o-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (218 aa) |
| | argS | arginyl-tRNA synthetase. (562 aa) |
| | rpmC | LSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (65 aa) |
| | rplP | LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (140 aa) |
| | rpsC | SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (216 aa) |
| | rplV | LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (110 aa) |
| | rpsS | SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa) |
| | rplB | LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa) |
| | rplW | LSU ribosomal protein L23P; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (96 aa) |
| | rplD | LSU ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (217 aa) |
| | rplC | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (218 aa) |
| | rpsJ | SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (109 aa) |
| | tuf | Protein translation Elongation Factor Tu (EF-TU); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (397 aa) |
| | radA | DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (538 aa) |
| | SYN_00970 | Chemotaxis protein methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (277 aa) |
| | cheB2 | Protein-glutamate methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (343 aa) |
| | SYN_00963 | Chemotaxis protein. (735 aa) |
| | SYN_00942 | Serine kinase of the HPr protein, regulates carbohydrate metabolism. (300 aa) |
| | lysS | lysyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (542 aa) |
| | frr | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | SYN_00915 | Membrane metalloprotease. (366 aa) |
| | SYN_00914 | Non-proteolytic protein peptidase M22 family, putative molecular chaperone. (240 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (597 aa) |
| | rpmB | Ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (65 aa) |
| | SYN_00869 | Glycerate dehydrogenase / hydroxypyruvate reductase; Bifunctional. (438 aa) |
| | prfC | Bacterial peptide Chain Release Factor 3 (RF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | SYN_00833 | Transglutaminase-like superfamily member. (588 aa) |
| | SYN_00822 | Glycosyltransferase involved in cell wall biogenesis. (263 aa) |
| | SYN_00819 | Glycosyltransferase involved in cell wall biogenesis. (264 aa) |
| | SYN_00815 | Dolichyl-phosphate-mannose-protein mannosyltransferase proteins. (559 aa) |
| | SYN_00812 | Metalloprotease, insulinase family. (1028 aa) |
| | lon | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (790 aa) |
| | rplS | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa) |
| | rpsP | SSU ribosomal protein S16P; Belongs to the bacterial ribosomal protein bS16 family. (83 aa) |
| | SYN_00748 | acetyl-CoA synthetase beta subunit. (773 aa) |
| | SYN_00741 | Transglutaminase-like enzymes, putative cysteine proteases. (651 aa) |
| | SYN_00735 | Hypothetical membrane protein. (88 aa) |
| | SYN_00734 | Uncharacterized protein involved in formate dehydrogenase formation; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (276 aa) |
| | SYN_00731 | NAD(FAD)-utilizing dehydrogenases. (433 aa) |
| | SYN_00688 | Neutral zinc metallopeptidase family. (285 aa) |
| | SYN_00647 | acetyl-CoA synthetase. (482 aa) |
| | SYN_00646 | acetyl-CoA synthetase (NDP-forming) beta subunit. (228 aa) |
| | rpsF | SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA. (173 aa) |
| | rpsR | SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (88 aa) |
| | rplI | LSU ribosomal protein L9P; Binds to the 23S rRNA. (149 aa) |
| | SYN_00636 | Protein involved in formate dehydrogenase formation; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (293 aa) |
| | SYN_00635 | Formate dehydrogenase major subunit; Cytochrome b. (195 aa) |
| | SYN_00634 | Formate dehydrogenase major subunit; Cytochrome b; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (811 aa) |
| | SYN_00611 | Hydrolase of the alpha/beta superfamily N. (264 aa) |
| | SYN_00603 | Formate dehydrogenase major subunit; Cytochrome b; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (830 aa) |
| | SYN_00602 | Formate dehydrogenase major subunit; Cytochrome b. (186 aa) |
| | SYN_00601 | hypE-like hydrogenase expression/formation protein. (336 aa) |
| | SYN_00600 | Hydrogenase maturation protein; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (778 aa) |
| | SYN_00599 | Ni2+ insertion GTPase. (219 aa) |
| | SYN_00598 | Hydrogenase isoenzymes formation protein; Belongs to the HypD family. (368 aa) |
| | SYN_00597 | Ni-Fe hydrogenase precursor-specific chaperone. (76 aa) |
| | hypA | hypA family hydrogenase nickel incorporation protein; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (114 aa) |
| | SYN_00581 | Peptide chain release factor. (136 aa) |
| | SYN_00575 | Type 4 prepilin-like proteins leader peptide processing enzyme; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (258 aa) |
| | SYN_00568 | Signal transduction histidine kinase with reciever domain protein. (649 aa) |
| | SYN_00566 | Sensory transduction protein with PAS domain. (531 aa) |
| | metG | methionyl-tRNA synthetase / protein secretion chaperonin; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (644 aa) |
| | SYN_00537 | Beta-propeller domain of methanol dehydrogenase type protein. (268 aa) |
| | SYN_00535 | LemA family protein. (191 aa) |
| | SYN_00527 | Trypsin-like serine protease; Belongs to the peptidase S1C family. (506 aa) |
| | mobA | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (199 aa) |
| | SYN_00476 | Hypothetical cytosolic protein; Belongs to the LarC family. (401 aa) |
| | SYN_00466 | ABC transporter ATP-binding protein. (675 aa) |
| | SYN_00441 | thiS family protein. (67 aa) |
| | SYN_00438 | thiF family protein. (210 aa) |
| | SYN_00431 | Chemotaxis protein. (786 aa) |
