(15 nodes) ATP-grasp fold network (Syntrophus aciditrophicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SYN_02878	acetyl-CoA synthetase / acetyltransferase (GNAT) family protein. (918 aa)
	SYN_03227	succinyl-CoA synthetase beta chain. (380 aa)
	SYN_02607	acetyl-CoA synthetase / acetyltransferase (GNAT) family protein. (899 aa)
	carB-2	Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1066 aa)
	sucC	succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (398 aa)
	purD	Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (462 aa)
	SYN_02112	acetyl-CoA synthetase beta subunit. (697 aa)
	SYN_01949	acyl-CoA synthetase; NDP forming. (727 aa)
	carB	Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1069 aa)
	ddl-2	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (352 aa)
	SYN_01041	Pyruvate carboxylase biotin carboxylase subunit. (486 aa)
	SYN_00748	acetyl-CoA synthetase beta subunit. (773 aa)
	SYN_00646	acetyl-CoA synthetase (NDP-forming) beta subunit. (228 aa)
	ddl	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (355 aa)
	SYN_00049	acetyl-CoA synthetase beta subunit. (701 aa)

Your Current Organism:

Syntrophus aciditrophicus

NCBI taxonomy Id: 56780
Other names: S. aciditrophicus SB, Syntrophus aciditrophicus SB, Syntrophus aciditrophicus str. SB, Syntrophus aciditrophicus strain SB

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SYN_00049	SYN_00646	SYN_00049	SYN_00646	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase (NDP-forming) beta subunit.	0.923
SYN_00049	SYN_01041	SYN_00049	SYN_01041	acetyl-CoA synthetase beta subunit.	Pyruvate carboxylase biotin carboxylase subunit.	0.800
SYN_00049	SYN_02112	SYN_00049	SYN_02112	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase beta subunit.	0.920
SYN_00049	SYN_03227	SYN_00049	SYN_03227	acetyl-CoA synthetase beta subunit.	succinyl-CoA synthetase beta chain.	0.802
SYN_00049	sucC	SYN_00049	SYN_02501	acetyl-CoA synthetase beta subunit.	succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.802
SYN_00646	SYN_00049	SYN_00646	SYN_00049	acetyl-CoA synthetase (NDP-forming) beta subunit.	acetyl-CoA synthetase beta subunit.	0.923
SYN_00646	SYN_01041	SYN_00646	SYN_01041	acetyl-CoA synthetase (NDP-forming) beta subunit.	Pyruvate carboxylase biotin carboxylase subunit.	0.800
SYN_00646	SYN_02112	SYN_00646	SYN_02112	acetyl-CoA synthetase (NDP-forming) beta subunit.	acetyl-CoA synthetase beta subunit.	0.916
SYN_00646	SYN_03227	SYN_00646	SYN_03227	acetyl-CoA synthetase (NDP-forming) beta subunit.	succinyl-CoA synthetase beta chain.	0.802
SYN_00646	sucC	SYN_00646	SYN_02501	acetyl-CoA synthetase (NDP-forming) beta subunit.	succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.802
SYN_01041	SYN_00049	SYN_01041	SYN_00049	Pyruvate carboxylase biotin carboxylase subunit.	acetyl-CoA synthetase beta subunit.	0.800
SYN_01041	SYN_00646	SYN_01041	SYN_00646	Pyruvate carboxylase biotin carboxylase subunit.	acetyl-CoA synthetase (NDP-forming) beta subunit.	0.800
SYN_01041	SYN_02112	SYN_01041	SYN_02112	Pyruvate carboxylase biotin carboxylase subunit.	acetyl-CoA synthetase beta subunit.	0.800
SYN_02112	SYN_00049	SYN_02112	SYN_00049	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase beta subunit.	0.920
SYN_02112	SYN_00646	SYN_02112	SYN_00646	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase (NDP-forming) beta subunit.	0.916
SYN_02112	SYN_01041	SYN_02112	SYN_01041	acetyl-CoA synthetase beta subunit.	Pyruvate carboxylase biotin carboxylase subunit.	0.800
SYN_02112	SYN_03227	SYN_02112	SYN_03227	acetyl-CoA synthetase beta subunit.	succinyl-CoA synthetase beta chain.	0.802
SYN_02112	sucC	SYN_02112	SYN_02501	acetyl-CoA synthetase beta subunit.	succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.802
SYN_03227	SYN_00049	SYN_03227	SYN_00049	succinyl-CoA synthetase beta chain.	acetyl-CoA synthetase beta subunit.	0.802
SYN_03227	SYN_00646	SYN_03227	SYN_00646	succinyl-CoA synthetase beta chain.	acetyl-CoA synthetase (NDP-forming) beta subunit.	0.802