(18 nodes) ATP-grasp fold, subdomain 1 network (Syntrophus aciditrophicus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

Your Input:
	ddl	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (355 aa)
	SYN_02966	Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (803 aa)
	SYN_03227	succinyl-CoA synthetase beta chain. (380 aa)
	SYN_02878	acetyl-CoA synthetase / acetyltransferase (GNAT) family protein. (918 aa)
	SYN_02609	acetyl-CoA synthetase beta subunit. (700 aa)
	SYN_02607	acetyl-CoA synthetase / acetyltransferase (GNAT) family protein. (899 aa)
	carB-2	Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1066 aa)
	sucC	succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (398 aa)
	uvrA	Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (940 aa)
	purD	Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (462 aa)
	SYN_02383	Phosphoenolpyruvate synthase. (907 aa)
	SYN_02112	acetyl-CoA synthetase beta subunit. (697 aa)
	SYN_01949	acyl-CoA synthetase; NDP forming. (727 aa)
	ddl-2	D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (352 aa)
	SYN_01243	Phosphoenolpyruvate synthase. (1070 aa)
	SYN_00748	acetyl-CoA synthetase beta subunit. (773 aa)
	SYN_00646	acetyl-CoA synthetase (NDP-forming) beta subunit. (228 aa)
	SYN_00049	acetyl-CoA synthetase beta subunit. (701 aa)

Your Current Organism:

Syntrophus aciditrophicus

NCBI taxonomy Id: 56780
Other names: S. aciditrophicus SB, Syntrophus aciditrophicus SB, Syntrophus aciditrophicus str. SB, Syntrophus aciditrophicus strain SB

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SYN_00049	SYN_00646	SYN_00049	SYN_00646	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase (NDP-forming) beta subunit.	0.923
SYN_00049	SYN_02112	SYN_00049	SYN_02112	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase beta subunit.	0.920
SYN_00049	SYN_02609	SYN_00049	SYN_02609	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase beta subunit.	0.926
SYN_00049	SYN_03227	SYN_00049	SYN_03227	acetyl-CoA synthetase beta subunit.	succinyl-CoA synthetase beta chain.	0.802
SYN_00049	sucC	SYN_00049	SYN_02501	acetyl-CoA synthetase beta subunit.	succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.802
SYN_00646	SYN_00049	SYN_00646	SYN_00049	acetyl-CoA synthetase (NDP-forming) beta subunit.	acetyl-CoA synthetase beta subunit.	0.923
SYN_00646	SYN_02112	SYN_00646	SYN_02112	acetyl-CoA synthetase (NDP-forming) beta subunit.	acetyl-CoA synthetase beta subunit.	0.916
SYN_00646	SYN_02609	SYN_00646	SYN_02609	acetyl-CoA synthetase (NDP-forming) beta subunit.	acetyl-CoA synthetase beta subunit.	0.916
SYN_00646	SYN_03227	SYN_00646	SYN_03227	acetyl-CoA synthetase (NDP-forming) beta subunit.	succinyl-CoA synthetase beta chain.	0.802
SYN_00646	sucC	SYN_00646	SYN_02501	acetyl-CoA synthetase (NDP-forming) beta subunit.	succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.802
SYN_02112	SYN_00049	SYN_02112	SYN_00049	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase beta subunit.	0.920
SYN_02112	SYN_00646	SYN_02112	SYN_00646	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase (NDP-forming) beta subunit.	0.916
SYN_02112	SYN_02609	SYN_02112	SYN_02609	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase beta subunit.	0.924
SYN_02112	SYN_03227	SYN_02112	SYN_03227	acetyl-CoA synthetase beta subunit.	succinyl-CoA synthetase beta chain.	0.802
SYN_02112	sucC	SYN_02112	SYN_02501	acetyl-CoA synthetase beta subunit.	succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.802
SYN_02607	SYN_02609	SYN_02607	SYN_02609	acetyl-CoA synthetase / acetyltransferase (GNAT) family protein.	acetyl-CoA synthetase beta subunit.	0.585
SYN_02609	SYN_00049	SYN_02609	SYN_00049	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase beta subunit.	0.926
SYN_02609	SYN_00646	SYN_02609	SYN_00646	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase (NDP-forming) beta subunit.	0.916
SYN_02609	SYN_02112	SYN_02609	SYN_02112	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase beta subunit.	0.924
SYN_02609	SYN_02607	SYN_02609	SYN_02607	acetyl-CoA synthetase beta subunit.	acetyl-CoA synthetase / acetyltransferase (GNAT) family protein.	0.585