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SYN_00049 SYN_00049 leuA leuA SYN_00115 SYN_00115 SYN_00154 SYN_00154 SYN_00155 SYN_00155 SYN_00156 SYN_00156 SYN_00157 SYN_00157 SYN_00158 SYN_00158 SYN_00159 SYN_00159 SYN_00265 SYN_00265 SYN_00316 SYN_00316 SYN_00318 SYN_00318 SYN_00517 SYN_00517 SYN_00646 SYN_00646 SYN_00691 SYN_00691 SYN_00692 SYN_00692 SYN_00693 SYN_00693 SYN_00694 SYN_00694 SYN_00718 SYN_00718 SYN_01040 SYN_01040 SYN_01041 SYN_01041 SYN_01158 SYN_01158 acsA acsA SYN_01287 SYN_01287 SYN_01431 SYN_01431 SYN_01434 SYN_01434 SYN_01681 SYN_01681 SYN_02086 SYN_02086 SYN_02112 SYN_02112 SYN_02143 SYN_02143 SYN_02194 SYN_02194 SYN_02201 SYN_02201 SYN_02498 SYN_02498 SYN_02499 SYN_02499 SYN_02597 SYN_02597 SYN_02609 SYN_02609 SYN_02635 SYN_02635 SYN_02642 SYN_02642 SYN_02709 SYN_02709 acyP acyP SYN_02952 SYN_02952 SYN_02966 SYN_02966 SYN_03162 SYN_03162 SYN_03163 SYN_03163
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYN_00049acetyl-CoA synthetase beta subunit. (701 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (516 aa)
SYN_00115Na+-transporting decarboxylase, beta subunit. (400 aa)
SYN_00154Pyruvate:ferredoxin oxidoreductase beta subunit. (323 aa)
SYN_00155Pyruvate:ferredoxin oxidoreductase alpha subunit. (391 aa)
SYN_00156Pyruvate:ferredoxin oxidoreductase delta subunit. (113 aa)
SYN_00157Pyruvate:ferredoxin oxidoreductase gamma subunit. (181 aa)
SYN_00158Fumarate hydratase beta subunit. (198 aa)
SYN_00159Fumarate hydratase alpha subunit. (284 aa)
SYN_00265NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (459 aa)
SYN_00316(s)-2-hydroxy-acid oxidase chain D. (509 aa)
SYN_00318Zn-dependent hydrolases, including glyoxylases. (222 aa)
SYN_00517NAD-dependent malic enzyme. (479 aa)
SYN_00646acetyl-CoA synthetase (NDP-forming) beta subunit. (228 aa)
SYN_00691Pyruvate synthase subunit. (304 aa)
SYN_00692Pyruvate synthase alpha chain. (370 aa)
SYN_00693Pyruvate synthase gamma chain. (175 aa)
SYN_00694Pyruvate synthase delta subunit. (83 aa)
SYN_00718Lactoylglutathione lyase. (123 aa)
SYN_01040Pyruvate carboxylase carboxyltransferase subunit. (653 aa)
SYN_01041Pyruvate carboxylase biotin carboxylase subunit. (486 aa)
SYN_01158Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family. (235 aa)
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (647 aa)
SYN_01287Hydroxyacylglutathione hydrolase. (485 aa)
SYN_01431glutaconyl-CoA decarboxylase beta subunit. (448 aa)
SYN_01434Na+-translocating decarboxylase, beta subunit. (406 aa)
SYN_01681acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa)
SYN_02086Phosphoenolpyruvate carboxykinase (ATP). (549 aa)
SYN_02112acetyl-CoA synthetase beta subunit. (697 aa)
SYN_02143Zn-dependent hydrolases. (215 aa)
SYN_021942-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (532 aa)
SYN_02201Pyruvate dehydrogenase (ferredoxin/flavodoxin-dependent). (1172 aa)
SYN_024982-oxoglutarate synthase subunit. (380 aa)
SYN_024992-oxoglutarate synthase subunit. (309 aa)
SYN_02597Propionate CoA-transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family. (531 aa)
SYN_02609acetyl-CoA synthetase beta subunit. (700 aa)
SYN_02635acetyl-CoA synthetase. (656 aa)
SYN_02642acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
SYN_02709Hydroxyacylglutathione hydrolase W. (257 aa)
acyPAcylphosphatase. (96 aa)
SYN_02952Pyruvate kinase; Belongs to the pyruvate kinase family. (475 aa)
SYN_02966Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (803 aa)
SYN_031622-oxoacid ferredoxin oxidoreductase, alpha subunit. (344 aa)
SYN_031632-oxoacid ferredoxin oxidoreductase, beta subunit. (274 aa)
Your Current Organism:
Syntrophus aciditrophicus
NCBI taxonomy Id: 56780
Other names: S. aciditrophicus SB, Syntrophus aciditrophicus SB, Syntrophus aciditrophicus str. SB, Syntrophus aciditrophicus strain SB
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