(7 nodes) Thiamine biosynthetic process network (Dickeya sp. NCPPB569)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	thiH	Unannotated protein. (382 aa)
	thiG	Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (259 aa)
	thiS	Unannotated protein. (66 aa)
	GCA_000406125_00208	Unannotated protein. (249 aa)
	thiE	Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (211 aa)
	thiC	Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (653 aa)
	thiD	Unannotated protein. (267 aa)

Your Current Organism:

Dickeya sp. NCPPB569

NCBI taxonomy Id: 568768
Other names: D. sp. NCPPB 569, Dickeya sp. NCPPB 569

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GCA_000406125_00208	thiC	GCA_000406125_00208	GCA_000406125_00210	Unannotated protein.	Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.959
GCA_000406125_00208	thiD	GCA_000406125_00208	GCA_000406125_02909	Unannotated protein.	Unannotated protein.	0.664
GCA_000406125_00208	thiE	GCA_000406125_00208	GCA_000406125_00209	Unannotated protein.	Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.973
GCA_000406125_00208	thiG	GCA_000406125_00208	GCA_000406125_00206	Unannotated protein.	Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.992
GCA_000406125_00208	thiH	GCA_000406125_00208	GCA_000406125_00205	Unannotated protein.	Unannotated protein.	0.978
GCA_000406125_00208	thiS	GCA_000406125_00208	GCA_000406125_00207	Unannotated protein.	Unannotated protein.	0.998
thiC	GCA_000406125_00208	GCA_000406125_00210	GCA_000406125_00208	Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Unannotated protein.	0.959
thiC	thiD	GCA_000406125_00210	GCA_000406125_02909	Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Unannotated protein.	0.995
thiC	thiE	GCA_000406125_00210	GCA_000406125_00209	Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.993
thiC	thiG	GCA_000406125_00210	GCA_000406125_00206	Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.991
thiC	thiH	GCA_000406125_00210	GCA_000406125_00205	Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Unannotated protein.	0.982
thiC	thiS	GCA_000406125_00210	GCA_000406125_00207	Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Unannotated protein.	0.958
thiD	GCA_000406125_00208	GCA_000406125_02909	GCA_000406125_00208	Unannotated protein.	Unannotated protein.	0.664
thiD	thiC	GCA_000406125_02909	GCA_000406125_00210	Unannotated protein.	Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.995
thiD	thiE	GCA_000406125_02909	GCA_000406125_00209	Unannotated protein.	Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.999
thiD	thiG	GCA_000406125_02909	GCA_000406125_00206	Unannotated protein.	Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.955
thiD	thiH	GCA_000406125_02909	GCA_000406125_00205	Unannotated protein.	Unannotated protein.	0.644
thiD	thiS	GCA_000406125_02909	GCA_000406125_00207	Unannotated protein.	Unannotated protein.	0.924
thiE	GCA_000406125_00208	GCA_000406125_00209	GCA_000406125_00208	Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	Unannotated protein.	0.973
thiE	thiC	GCA_000406125_00209	GCA_000406125_00210	Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.993