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| | ttuD | Hydroxypyruvate reductase; COG2379. (409 aa) |
| | mnmA | Conserved hypothetical protein; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (357 aa) |
| | Acin_0193 | Two-component system sensor histidine kinase. (473 aa) |
| | Acin_0201 | Conserved hypothetical protein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. (336 aa) |
| | trmB | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (212 aa) |
| | Acin_0223 | Conserved hypothetical protein. (468 aa) |
| | npdA | NAD-dependent deacetylase; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. (245 aa) |
| | Acin_0252 | Conserved hypothetical protein; COG1704. (184 aa) |
| | rlmH | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (160 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (312 aa) |
| | Acin_0351 | SUN protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (445 aa) |
| | rlmN | Ribosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (352 aa) |
| | Acin_0353 | Conserved hypothetical protein. (243 aa) |
| | Acin_0354 | Serine/threonine protein kinase. (649 aa) |
| | trmD | tRNA-(guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (246 aa) |
| | Acin_0423 | Conserved hypothetical protein. (252 aa) |
| | truA | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (253 aa) |
| | Acin_0477 | Conserved hypothetical protein. (153 aa) |
| | Acin_0478 | Peptidase M22. (230 aa) |
| | Acin_0479 | Conserved hypothetical protein; Acetylates the N-terminal alanine of ribosomal protein S18. (153 aa) |
| | tsaD | Conserved hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (340 aa) |
| | map | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (272 aa) |
| | Acin_0499 | Conserved hypothetical protein; Belongs to the TtcA family. (261 aa) |
| | Acin_0512 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (191 aa) |
| | Acin_0548 | Putative metal-dependent enzyme; COG3872. (293 aa) |
| | prmC | Modification methylase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. (298 aa) |
| | Acin_0650 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (318 aa) |
| | Acin_0679 | Type III restriction system methyltransferase; COG2189. (629 aa) |
| | Acin_0682 | Phosphotyrosine protein phosphatase; COG0394; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (166 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (374 aa) |
| | acpS | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (124 aa) |
| | tilS | Hypoxanthine phosphoribosyltransferase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (348 aa) |
| | birA | biotin-(acetyl-CoA carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (331 aa) |
| | Acin_0795 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (325 aa) |
| | Acin_0834 | RNA methyltransferase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (263 aa) |
| | miaB | RNA modification enzyme; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (441 aa) |
| | Acin_0936 | Conserved hypothetical protein. (266 aa) |
| | Acin_0948 | Conserved hypothetical protein. (235 aa) |
| | Acin_0982 | Conserved hypothetical protein. (341 aa) |
| | rsmI | uroporphyrin-III C/tetrapyrrole methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (264 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (287 aa) |
| | Acin_1080 | Two-component system sensor histidine kinase. (420 aa) |
| | Acin_1103 | O-sialoglycoprotein endopeptidase. (322 aa) |
| | Acin_1124 | Pseudouridine synthase. (296 aa) |
| | rimO | Conserved hypothetical protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (442 aa) |
| | Acin_1172 | Pseudouridine synthase; COG1187. (73 aa) |
| | Acin_1173 | Pseudouridine synthase; COG1187; Belongs to the pseudouridine synthase RsuA family. (183 aa) |
| | trmFO | Conserved hypothetical protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (442 aa) |
| | Acin_1239 | Conserved hypothetical protein. (495 aa) |
| | phoR | Two-component system sensor histidine kinase. (532 aa) |
| | dcm | DNA-cytosine methyltransferase. (355 aa) |
| | Acin_1345 | Conserved hypothetical protein; COG4695. (429 aa) |
| | dcm-2 | DNA-cytosine methyltransferase; COG0270; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (503 aa) |
| | Acin_1352 | Methylase; COG1475; Belongs to the N(4)/N(6)-methyltransferase family. (416 aa) |
| | Acin_1459 | RNA methyltransferase; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily. (155 aa) |
| | rsmH | S-adenosyl-methyltransferase mraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (311 aa) |
| | truB | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (288 aa) |
| | Acin_1617 | Radical SAM family protein. (332 aa) |
| | tmcAL | Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (402 aa) |
| | Acin_1635 | Pantetheine-phosphate adenylyltransferase. (185 aa) |
| | Acin_1646 | RNA modification enzyme; COG0621. (435 aa) |
| | prmA | 50S ribosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (316 aa) |
| | baeS | Two-component system sensor histidine kinase. (383 aa) |
| | arcB | Two-component system sensor histidine kinase and response regulator. (578 aa) |
| | Acin_1728 | Conserved hypothetical protein; COG1670. (175 aa) |
| | tadA | CMP/dCMP deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (153 aa) |
| | Acin_1868 | RNA methyltransferase; COG2265; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (463 aa) |
| | Acin_1885 | Site-specific DNA-methyltransferase. (438 aa) |
| | Acin_1886 | Restriction endonuclease BglII; NOG75413. (239 aa) |
| | Acin_1919 | HK97 family portal protein, putative; COG4695. (375 aa) |
| | Acin_1927 | DNA methylase N-4/N-6 domain protein; COG1475; Belongs to the N(4)/N(6)-methyltransferase family. (418 aa) |
| | Acin_1976 | Conserved hypothetical protein; COG4695. (418 aa) |
| | Acin_1984 | Methylase; COG1475; Belongs to the N(4)/N(6)-methyltransferase family. (407 aa) |
| | Acin_1989 | Hypothetical protein. (350 aa) |
| | phoR-2 | Two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR. (487 aa) |
| | thiF | Adenylyltransferase ThiF; COG0476. (209 aa) |
| | Acin_2158 | Glycosyl transferase. (247 aa) |
| | Acin_2166 | Conserved hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (282 aa) |
| | Acin_2181 | Glycosyl transferase. (545 aa) |
| | Acin_2220 | RNA methyltransferase; COG0566; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (249 aa) |
| | Acin_2371 | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (155 aa) |
| | Acin_2384 | Conserved hypothetical protein. (469 aa) |
| | Acin_2434 | Two-component system sensor histidine kinase. (495 aa) |
| | Acin_2435 | Glycosyl transferase. (493 aa) |
| | rsmG | Ribosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (242 aa) |
| | mnmG | tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (626 aa) |
| | mnmE | Thiophene and furan oxidation protein thdF; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (455 aa) |
