(15 nodes) Cellular response to chemical stimulus network (Acidaminococcus intestini)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Acin_1757	Conserved hypothetical protein; COG1827. (168 aa)
	pcaC	4-carboxymuconolactone decarboxylase. (276 aa)
	Acin_1638	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
	trxB	Thioredoxin reductase (NADPH); COG0526. (558 aa)
	Acin_1414	Conserved hypothetical protein; COG1225. (151 aa)
	Acin_1407	Rubredoxin/rubrerythrin; COG1592. (182 aa)
	Acin_1207	Conserved hypothetical protein; COG2033. (126 aa)
	Acin_1085	Hypothetical protein. (129 aa)
	tpx	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (171 aa)
	Acin_0752	Conserved hypothetical protein; COG1592. (180 aa)
	Acin_0609	Rubrerythrin. (179 aa)
	hcp	Conserved hypothetical protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (540 aa)
	trxB-2	Thioredoxin-disulfide reductase. (283 aa)
	Acin_2120	NAD(FAD)-dependent dehydrogenase; COG0446. (419 aa)
	Acin_2034	Gamma-aminobutyrate metabolism dehydratase/isomerase; COG2368. (473 aa)

Your Current Organism:

Acidaminococcus intestini

NCBI taxonomy Id: 568816
Other names: A. intestini RyC-MR95, Acidaminococcus intestini RyC-MR95, Acidaminococcus intestini strain RyC-MR95

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Acin_0752	Acin_1207	Acin_0752	Acin_1207	Conserved hypothetical protein; COG1592.	Conserved hypothetical protein; COG2033.	0.448
Acin_1207	Acin_0752	Acin_1207	Acin_0752	Conserved hypothetical protein; COG2033.	Conserved hypothetical protein; COG1592.	0.448
Acin_1207	Acin_1638	Acin_1207	Acin_1638	Conserved hypothetical protein; COG2033.	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	0.408
Acin_1414	Acin_1638	Acin_1414	Acin_1638	Conserved hypothetical protein; COG1225.	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	0.443
Acin_1414	trxB	Acin_1414	Acin_1637	Conserved hypothetical protein; COG1225.	Thioredoxin reductase (NADPH); COG0526.	0.431
Acin_1638	Acin_1207	Acin_1638	Acin_1207	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	Conserved hypothetical protein; COG2033.	0.408
Acin_1638	Acin_1414	Acin_1638	Acin_1414	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	Conserved hypothetical protein; COG1225.	0.443
Acin_1638	Acin_2120	Acin_1638	Acin_2120	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	NAD(FAD)-dependent dehydrogenase; COG0446.	0.603
Acin_1638	tpx	Acin_1638	Acin_1044	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	0.477
Acin_1638	trxB	Acin_1638	Acin_1637	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	Thioredoxin reductase (NADPH); COG0526.	0.994
Acin_1638	trxB-2	Acin_1638	Acin_2373	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	Thioredoxin-disulfide reductase.	0.621
Acin_2120	Acin_1638	Acin_2120	Acin_1638	NAD(FAD)-dependent dehydrogenase; COG0446.	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	0.603
tpx	Acin_1638	Acin_1044	Acin_1638	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	0.477
tpx	trxB	Acin_1044	Acin_1637	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	Thioredoxin reductase (NADPH); COG0526.	0.611
trxB	Acin_1414	Acin_1637	Acin_1414	Thioredoxin reductase (NADPH); COG0526.	Conserved hypothetical protein; COG1225.	0.431
trxB	Acin_1638	Acin_1637	Acin_1638	Thioredoxin reductase (NADPH); COG0526.	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	0.994
trxB	tpx	Acin_1637	Acin_1044	Thioredoxin reductase (NADPH); COG0526.	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.	0.611
trxB	trxB-2	Acin_1637	Acin_2373	Thioredoxin reductase (NADPH); COG0526.	Thioredoxin-disulfide reductase.	0.937
trxB-2	Acin_1638	Acin_2373	Acin_1638	Thioredoxin-disulfide reductase.	Conserved hypothetical protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.	0.621
trxB-2	trxB	Acin_2373	Acin_1637	Thioredoxin-disulfide reductase.	Thioredoxin reductase (NADPH); COG0526.	0.937