(97 nodes) Actin cytoskeleton organization network (Cladophialophora immunda)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV07_10807	Uncharacterized protein. (395 aa)
	PV07_10452	VHS domain-containing protein. (542 aa)
	PV07_12014	GTP-binding protein rho2. (202 aa)
	PV07_10289	Aldolase_II domain-containing protein. (285 aa)
	PV07_11553	Uncharacterized protein. (1009 aa)
	PV07_09837	Aldolase_II domain-containing protein. (303 aa)
	PV07_11780	Uncharacterized protein. (209 aa)
	PV07_11064	ANK_REP_REGION domain-containing protein. (609 aa)
	PV07_11198	Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1261 aa)
	PV07_12178	Uncharacterized protein. (427 aa)
	PV07_12476	Uncharacterized protein. (654 aa)
	PV07_12492	TYR_PHOSPHATASE_2 domain-containing protein. (656 aa)
	PV07_00443	Aldolase_II domain-containing protein. (314 aa)
	PV07_03617	Uncharacterized protein. (2233 aa)
	PV07_03128	Uncharacterized protein. (203 aa)
	PV07_02653	Uncharacterized protein. (766 aa)
	PV07_05751	SH3 domain-containing protein. (403 aa)
	PV07_05450	Cell division control protein 42, variant 1. (193 aa)
	PV07_07660	DUF2013 domain-containing protein. (871 aa)
	PV07_00637	SH3 domain-containing protein. (953 aa)
	PV07_12458	WD_REPEATS_REGION domain-containing protein. (626 aa)
	PV07_12295	Adenylyl cyclase-associated protein; Belongs to the CAP family. (525 aa)
	PV07_10866	Uncharacterized protein. (1171 aa)
	PV07_11656	Zn(2)-C6 fungal-type domain-containing protein. (455 aa)
	PV07_10460	F-box domain-containing protein. (305 aa)
	PV07_08819	Uncharacterized protein. (1059 aa)
	PV07_09081	Drf_GBD domain-containing protein. (865 aa)
	PV07_06487	Uncharacterized protein. (1805 aa)
	PV07_00457	Uncharacterized protein. (394 aa)
	PV07_02286	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (191 aa)
	PV07_01978	Coronin; Belongs to the WD repeat coronin family. (596 aa)
	PV07_04072	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (130 aa)
	PV07_02962	AIP3 domain-containing protein. (1141 aa)
	PV07_06372	Uncharacterized protein. (161 aa)
	PV07_05748	Uncharacterized protein. (650 aa)
	PV07_07988	Uncharacterized protein. (382 aa)
	PV07_01925	Aldolase_II domain-containing protein. (303 aa)
	PV07_06717	Uncharacterized protein. (730 aa)
	PV07_01186	Uncharacterized protein. (491 aa)
	PV07_00988	DUF4045 domain-containing protein. (1675 aa)
	PV07_00620	Uncharacterized protein. (442 aa)
	PV07_03979	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (319 aa)
	PV07_09088	BTB domain-containing protein. (287 aa)
	PV07_00373	Uncharacterized protein. (369 aa)
	PV07_00300	Uncharacterized protein. (1191 aa)
	PV07_00068	Uncharacterized protein. (195 aa)
	PV07_04517	Uncharacterized protein. (139 aa)
	PV07_10769	Uncharacterized protein. (253 aa)
	PV07_03080	Uncharacterized protein. (397 aa)
	PV07_10595	ENTH domain-containing protein. (570 aa)
	PV07_04093	Uncharacterized protein. (1301 aa)
	PV07_04031	Chitin synthase 1. (1037 aa)
	PV07_02945	Uncharacterized protein. (745 aa)
	PV07_03737	GTP-binding protein rhoA. (193 aa)
	PV07_03569	Uncharacterized protein. (644 aa)
	PV07_02907	Uncharacterized protein. (396 aa)
	PV07_05893	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (365 aa)
	PV07_02634	WW domain-containing protein. (225 aa)
	PV07_05588	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (189 aa)
	PV07_11409	Uncharacterized protein. (614 aa)
	PV07_02429	ENTH domain-containing protein. (548 aa)
	PV07_00154	Uncharacterized protein; Belongs to the actin family. (439 aa)
	PV07_12810	Uncharacterized protein; Belongs to the protein kinase superfamily. (472 aa)
	PV07_12174	Uncharacterized protein. (412 aa)
	PV07_11708	Uncharacterized protein. (1186 aa)
	PV07_11741	Zn(2)-C6 fungal-type domain-containing protein. (928 aa)
	PV07_10109	Uncharacterized protein. (376 aa)
	PV07_10743	Protein kinase domain-containing protein. (1008 aa)
	PV07_08477	MHD domain-containing protein. (876 aa)
	PV07_08586	Uncharacterized protein. (735 aa)
	PV07_06634	Aldolase_II domain-containing protein. (285 aa)
	PV07_06881	GTP-binding protein rhoC. (275 aa)
	PV07_07100	Uncharacterized protein. (756 aa)
	PV07_07163	Uncharacterized protein. (100 aa)
	PV07_07300	Uncharacterized protein. (668 aa)
	PV07_07598	DAO domain-containing protein. (485 aa)
	PV07_04963	DAO domain-containing protein. (489 aa)
	PV07_05175	Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (828 aa)
	PV07_05915	Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (388 aa)
	PV07_06174	Zn(2)-C6 fungal-type domain-containing protein. (637 aa)
	PV07_04126	Aldolase_II domain-containing protein. (299 aa)
	PV07_04244	Uncharacterized protein. (640 aa)
	PV07_04371	SH3 domain-containing protein. (1195 aa)
	PV07_04547	ANK_REP_REGION domain-containing protein. (319 aa)
	PV07_11015	Uncharacterized protein. (323 aa)
	PV07_04942	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (273 aa)
	PV07_05718	C3H1-type domain-containing protein. (282 aa)
	PV07_12475	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (279 aa)
	PV07_04819	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (152 aa)
	PV07_07176	Protein hob3. (261 aa)
	PV07_06848	Uncharacterized protein. (741 aa)
	PV07_06718	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
	PV07_06934	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1442 aa)
	PV07_09529	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1679 aa)
	PV07_06662	Actin, gamma, variant. (375 aa)
	PV07_06613	Uncharacterized protein. (264 aa)
	PV07_06452	Uncharacterized protein. (639 aa)

Your Current Organism:

Cladophialophora immunda

NCBI taxonomy Id: 569365
Other names: C. immunda, CBS 834.96, Cladophialophora sp. CBS 834.96, Cladophialophora sp. HB-2008

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV07_00068	PV07_03128	A0A0D2CPN2	A0A0D2B1J2	Uncharacterized protein.	Uncharacterized protein.	0.922
PV07_00068	PV07_03737	A0A0D2CPN2	A0A0D2CLS3	Uncharacterized protein.	GTP-binding protein rhoA.	0.930
PV07_00068	PV07_04819	A0A0D2CPN2	A0A0D2CD15	Uncharacterized protein.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.513
PV07_00068	PV07_04963	A0A0D2CPN2	A0A0D1ZME1	Uncharacterized protein.	DAO domain-containing protein.	0.868
PV07_00068	PV07_05450	A0A0D2CPN2	A0A0D2AWJ7	Uncharacterized protein.	Cell division control protein 42, variant 1.	0.979
PV07_00068	PV07_06662	A0A0D2CPN2	A0A0D2C6T8	Uncharacterized protein.	Actin, gamma, variant.	0.506
PV07_00068	PV07_06881	A0A0D2CPN2	A0A0D1ZGR6	Uncharacterized protein.	GTP-binding protein rhoC.	0.924
PV07_00068	PV07_07598	A0A0D2CPN2	A0A0D1ZIV4	Uncharacterized protein.	DAO domain-containing protein.	0.868
PV07_00068	PV07_10109	A0A0D2CPN2	A0A0D1Z9L9	Uncharacterized protein.	Uncharacterized protein.	0.575
PV07_00068	PV07_11064	A0A0D2CPN2	A0A0D2BWQ4	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.897
PV07_00068	PV07_11708	A0A0D2CPN2	A0A0D1Z7G9	Uncharacterized protein.	Uncharacterized protein.	0.426
PV07_00068	PV07_11780	A0A0D2CPN2	A0A0D2BWY6	Uncharacterized protein.	Uncharacterized protein.	0.897
PV07_00068	PV07_12014	A0A0D2CPN2	A0A0D2BZV6	Uncharacterized protein.	GTP-binding protein rho2.	0.900
PV07_00154	PV07_00457	A0A0D1ZYT7	A0A0D1ZZP9	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.570
PV07_00154	PV07_00620	A0A0D1ZYT7	A0A0D2CRF0	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.475
PV07_00154	PV07_00988	A0A0D1ZYT7	A0A0D2CSN5	Uncharacterized protein; Belongs to the actin family.	DUF4045 domain-containing protein.	0.459
PV07_00154	PV07_01978	A0A0D1ZYT7	A0A0D2DHN6	Uncharacterized protein; Belongs to the actin family.	Coronin; Belongs to the WD repeat coronin family.	0.542
PV07_00154	PV07_02286	A0A0D1ZYT7	A0A0D2DIU3	Uncharacterized protein; Belongs to the actin family.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.998
PV07_00154	PV07_02653	A0A0D1ZYT7	A0A0D2B098	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.857
PV07_00154	PV07_02907	A0A0D1ZYT7	A0A0D2CJC0	Uncharacterized protein; Belongs to the actin family.	Uncharacterized protein.	0.534