STRINGSTRING
PV07_08908 PV07_08908 PV07_04601 PV07_04601 PV07_05680 PV07_05680 CFD1 CFD1 PV07_02384 PV07_02384 PV07_08136 PV07_08136 PV07_00667 PV07_00667 PV07_01181 PV07_01181 PV07_04270 PV07_04270 PV07_03964 PV07_03964 PV07_03566 PV07_03566 PV07_08425 PV07_08425 PV07_03436 PV07_03436 PV07_09899 PV07_09899 PV07_11955 PV07_11955 PV07_02788 PV07_02788 NTH1 NTH1 PV07_09510 PV07_09510 PV07_09414 PV07_09414 PV07_09351 PV07_09351 PV07_09275 PV07_09275 PV07_08532 PV07_08532 PV07_09014 PV07_09014 PV07_08975 PV07_08975 PV07_10686 PV07_10686 PV07_08933 PV07_08933 PV07_09701 PV07_09701 PV07_10947 PV07_10947 NBP35 NBP35 DRE2 DRE2 PV07_03751 PV07_03751 PV07_02994 PV07_02994 PV07_02943 PV07_02943 PV07_05185 PV07_05185 PV07_09588 PV07_09588 PV07_10777 PV07_10777 PV07_00066 PV07_00066 PV07_04414 PV07_04414 PV07_03403 PV07_03403 PV07_03252 PV07_03252 PV07_07868 PV07_07868 PV07_06788 PV07_06788 PV07_09673 PV07_09673 PV07_10619 PV07_10619 PV07_11803 PV07_11803 PV07_11439 PV07_11439
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PV07_08908Nitrite reductase [NAD(P)H], large subunit. (1125 aa)
PV07_04601DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2240 aa)
PV07_05680Uncharacterized protein. (321 aa)
CFD1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (321 aa)
PV07_02384Rhodanese domain-containing protein. (584 aa)
PV07_08136NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial. (231 aa)
PV07_00667Flavodoxin-like domain-containing protein. (796 aa)
PV07_01181Sulfite reductase (NADPH) hemoprotein, beta-component. (1552 aa)
PV07_042703-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (772 aa)
PV07_03964DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (503 aa)
PV07_03566Uncharacterized protein. (1693 aa)
PV07_08425Uncharacterized protein. (182 aa)
PV07_03436Uncharacterized protein. (464 aa)
PV07_09899Uncharacterized protein. (831 aa)
PV07_11955Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (636 aa)
PV07_02788Molybdenum cofactor biosynthesis protein A. (928 aa)
NTH1Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (433 aa)
PV07_09510Biotin synthase. (411 aa)
PV07_09414Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (297 aa)
PV07_093512-(3-amino-3-carboxypropyl)histidine synthase subunit 2; Required for the first step in the synthesis of diphthamide, a post-translational modification of histidine which occurs in translation elongation factor 2; Belongs to the DPH1/DPH2 family. DPH2 subfamily. (578 aa)
PV07_09275Uncharacterized protein. (696 aa)
PV07_08532Uncharacterized protein. (289 aa)
PV07_09014DNA polymerase. (1699 aa)
PV07_089752-(3-amino-3-carboxypropyl)histidine synthase subunit 1; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2. (446 aa)
PV07_10686Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (420 aa)
PV07_08933Uncharacterized protein. (833 aa)
PV07_09701DNA repair helicase rad15, variant. (815 aa)
PV07_10947Nfu_N domain-containing protein. (316 aa)
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (342 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (330 aa)
PV07_03751MaoC-like domain-containing protein. (372 aa)
PV07_02994Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family. (605 aa)
PV07_02943Translation initiation factor RLI1. (604 aa)
PV07_05185NADH-ubiquinone oxidoreductase 78 kDa subunit, mitochondrial; Belongs to the complex I 75 kDa subunit family. (741 aa)
PV07_09588Uncharacterized protein. (1057 aa)
PV07_10777Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (575 aa)
PV07_00066DNA polymerase. (1107 aa)
PV07_04414Fe-S_biosyn domain-containing protein. (227 aa)
PV07_03403Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (809 aa)
PV07_03252NADH-ubiquinone oxidoreductase 19.3 kDa subunit, mitochondrial; Belongs to the complex I 20 kDa subunit family. (232 aa)
PV07_07868Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (748 aa)
PV07_06788Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (804 aa)
PV07_09673Uncharacterized protein. (1453 aa)
PV07_10619NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (506 aa)
PV07_11803Uncharacterized protein. (664 aa)
PV07_11439NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. (496 aa)
Your Current Organism:
Cladophialophora immunda
NCBI taxonomy Id: 569365
Other names: C. immunda, CBS 834.96, Cladophialophora sp. CBS 834.96, Cladophialophora sp. HB-2008
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