(112 nodes) Propanoate metabolism network (Cladophialophora immunda)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PV07_11658	Uncharacterized protein. (316 aa)
	PV07_10890	Epimerase domain-containing protein. (367 aa)
	PV07_05982	Uncharacterized protein. (264 aa)
	PV07_04662	Uncharacterized protein. (340 aa)
	PV07_07340	Uncharacterized protein. (323 aa)
	PV07_06605	Epimerase domain-containing protein. (358 aa)
	PV07_06550	Uncharacterized protein. (697 aa)
	PV07_09672	Uncharacterized protein. (292 aa)
	PV07_09639	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (690 aa)
	PV07_08841	Uncharacterized protein. (96 aa)
	PV07_08426	Uncharacterized protein. (325 aa)
	PV07_10631	CoA carboxyltransferase C-terminal domain-containing protein. (836 aa)
	PV07_10486	Uncharacterized protein. (2293 aa)
	PV07_10735	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (305 aa)
	PV07_10721	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (639 aa)
	PV07_09963	Uncharacterized protein. (103 aa)
	PV07_09872	Uncharacterized protein. (585 aa)
	PV07_10471	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (707 aa)
	PV07_11581	Uncharacterized protein. (272 aa)
	PV07_09898	Uncharacterized protein. (310 aa)
	PV07_11321	Methylmalonate-semialdehyde dehydrogenase (Acylating). (557 aa)
	PV07_11304	Uncharacterized protein. (1259 aa)
	PV07_11906	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (276 aa)
	PV07_12427	MaoC-like domain-containing protein. (907 aa)
	PV07_12230	Uncharacterized protein. (83 aa)
	PV07_02342	Acetyl-coenzyme A synthetase. (671 aa)
	PV07_02313	Uncharacterized protein. (333 aa)
	PV07_01802	Uncharacterized protein. (278 aa)
	PV07_01701	Epimerase domain-containing protein. (348 aa)
	PV07_01190	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (330 aa)
	PV07_01057	Epimerase domain-containing protein. (375 aa)
	PV07_00606	Epimerase domain-containing protein. (401 aa)
	PV07_03919	Uncharacterized protein. (528 aa)
	PV07_03871	Uncharacterized protein. (339 aa)
	PV07_03743	Uncharacterized protein. (315 aa)
	PV07_05266	Probable acetate kinase. (437 aa)
	PV07_08029	Uncharacterized protein. (348 aa)
	PV07_06513	2-methylcitrate dehydratase. (552 aa)
	PV07_09274	Uncharacterized protein. (317 aa)
	PV07_09200	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (457 aa)
	PV07_08979	Phosphonopyruvate hydrolase. (301 aa)
	PV07_10620	Uncharacterized protein. (709 aa)
	PV07_10590	Uncharacterized protein. (314 aa)
	PV07_10019	Uncharacterized protein. (402 aa)
	PV07_09689	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
	PV07_11977	Uncharacterized protein. (341 aa)
	PV07_11750	Epimerase domain-containing protein. (345 aa)
	PV07_11464	Epimerase domain-containing protein. (331 aa)
	PV07_12425	SET domain-containing protein. (485 aa)
	PV07_12229	Uncharacterized protein. (178 aa)
	PV07_02361	Methylmalonate-semialdehyde dehydrogenase (Acylating). (568 aa)
	PV07_02197	Uncharacterized protein. (366 aa)
	PV07_02128	MaoC-like domain-containing protein. (304 aa)
	PV07_01686	Uncharacterized protein. (327 aa)
	PV07_01254	Uncharacterized protein. (325 aa)
	PV07_00922	Uncharacterized protein. (315 aa)
	PV07_00750	PKS_ER domain-containing protein. (374 aa)
	PV07_00544	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (275 aa)
	PV07_00524	Uncharacterized protein. (394 aa)
	PV07_04309	Peroxisomal hydratase-dehydrogenase-epimerase. (899 aa)
	PV07_02578	4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (434 aa)
	PV07_05056	ADH_N domain-containing protein. (453 aa)
	PV07_08143	Dihydrolipoyl dehydrogenase. (516 aa)
	PV07_07967	Uncharacterized protein. (353 aa)
	PV07_07295	Epimerase domain-containing protein. (436 aa)
	PV07_07012	Uncharacterized protein. (290 aa)
	PV07_06943	4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (521 aa)
	PV07_08528	SET domain-containing protein. (381 aa)
	PV07_10776	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (333 aa)
	PV07_11109	Uncharacterized protein. (333 aa)
	PV07_10814	Uncharacterized protein. (356 aa)
	PV07_01421	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (447 aa)
	PV07_01242	Uncharacterized protein. (318 aa)
	PV07_01072	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (522 aa)
	PV07_00689	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (686 aa)
	PV07_00394	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (706 aa)
	PV07_04579	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (291 aa)
	PV07_04104	Uncharacterized protein. (254 aa)
	PV07_02615	Uncharacterized protein. (737 aa)
	PV07_02557	Uncharacterized protein. (279 aa)
	PV07_05059	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (467 aa)
	PV07_05014	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (284 aa)
	PV07_01422	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (495 aa)
	PV07_01281	Uncharacterized protein. (528 aa)
	PV07_01991	Transket_pyr domain-containing protein. (390 aa)
	PV07_01425	Uncharacterized protein. (434 aa)
	PV07_01420	Transket_pyr domain-containing protein. (392 aa)
	PV07_04611	Uncharacterized protein. (324 aa)
	PV07_04575	Epimerase domain-containing protein. (367 aa)
	PV07_04495	3-hydroxyisobutyrate dehydrogenase. (342 aa)
	PV07_00769	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (340 aa)
	PV07_04136	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (443 aa)
	PV07_09097	Uncharacterized protein. (650 aa)
	PV07_00313	Uncharacterized protein. (401 aa)
	PV07_08938	Uncharacterized protein. (581 aa)
	PV07_08889	Uncharacterized protein. (351 aa)
	PV07_08840	Uncharacterized protein. (192 aa)
	PV07_08576	Epimerase domain-containing protein. (375 aa)
	PV07_08516	Uncharacterized protein. (1527 aa)
	PV07_08385	Uncharacterized protein. (363 aa)
	PV07_04123	Uncharacterized protein. (172 aa)
	PV07_03972	Uncharacterized protein. (309 aa)
	PV07_10424	Epimerase domain-containing protein. (340 aa)
	PV07_02899	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (698 aa)
	PV07_02886	Uncharacterized protein. (306 aa)
	PV07_03803	Uncharacterized protein. (2028 aa)
	PV07_09871	Uncharacterized protein. (910 aa)
	PV07_03199	CoA_binding domain-containing protein. (696 aa)
	PV07_03142	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (504 aa)
	PV07_11912	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (438 aa)
	PV07_02897	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (324 aa)
	PV07_11711	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa)

Your Current Organism:

Cladophialophora immunda

NCBI taxonomy Id: 569365
Other names: C. immunda, CBS 834.96, Cladophialophora sp. CBS 834.96, Cladophialophora sp. HB-2008

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PV07_00313	PV07_01190	A0A0D2CQI6	A0A0D2B9Y5	Uncharacterized protein.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.795
PV07_00313	PV07_01281	A0A0D2CQI6	A0A0D2CXF4	Uncharacterized protein.	Uncharacterized protein.	0.910
PV07_00313	PV07_01420	A0A0D2CQI6	A0A0D2CU11	Uncharacterized protein.	Transket_pyr domain-containing protein.	0.505
PV07_00313	PV07_01421	A0A0D2CQI6	A0A0D2DG08	Uncharacterized protein.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.457
PV07_00313	PV07_01422	A0A0D2CQI6	A0A0D2CXN9	Uncharacterized protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.808
PV07_00313	PV07_01991	A0A0D2CQI6	A0A0D2CW05	Uncharacterized protein.	Transket_pyr domain-containing protein.	0.505
PV07_00313	PV07_02897	A0A0D2CQI6	A0A0D2CJB3	Uncharacterized protein.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.795
PV07_00313	PV07_03142	A0A0D2CQI6	A0A0D2CK51	Uncharacterized protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.808
PV07_00313	PV07_03199	A0A0D2CQI6	A0A0D2CK93	Uncharacterized protein.	CoA_binding domain-containing protein.	0.980
PV07_00313	PV07_08143	A0A0D2CQI6	A0A0D1ZKH6	Uncharacterized protein.	Dihydrolipoyl dehydrogenase.	0.910
PV07_00313	PV07_08528	A0A0D2CQI6	A0A0D1ZC60	Uncharacterized protein.	SET domain-containing protein.	0.585
PV07_00313	PV07_08938	A0A0D2CQI6	A0A0D2CQB7	Uncharacterized protein.	Uncharacterized protein.	0.577
PV07_00313	PV07_09200	A0A0D2CQI6	A0A0D2ALX8	Uncharacterized protein.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.457
PV07_00313	PV07_09871	A0A0D2CQI6	A0A0D2CKR9	Uncharacterized protein.	Uncharacterized protein.	0.547
PV07_00313	PV07_09872	A0A0D2CQI6	A0A0D2C0Z1	Uncharacterized protein.	Uncharacterized protein.	0.547
PV07_00313	PV07_10486	A0A0D2CQI6	A0A0D2C2S0	Uncharacterized protein.	Uncharacterized protein.	0.770
PV07_00313	PV07_10620	A0A0D2CQI6	A0A0D2AJ81	Uncharacterized protein.	Uncharacterized protein.	0.585
PV07_00313	PV07_10631	A0A0D2CQI6	A0A0D2C3E0	Uncharacterized protein.	CoA carboxyltransferase C-terminal domain-containing protein.	0.577
PV07_00313	PV07_10735	A0A0D2CQI6	A0A0D2C199	Uncharacterized protein.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.795
PV07_00313	PV07_10776	A0A0D2CQI6	A0A0D1ZBL1	Uncharacterized protein.	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.980