STRINGSTRING
prkA2 prkA2 phoR phoR pk1 pk1 pfkA2 pfkA2 ptgCB2 ptgCB2 arcC2 arcC2 AMO57467.1 AMO57467.1 AMO57466.1 AMO57466.1 AMO57436.1 AMO57436.1 aceK aceK arcC1 arcC1 glxK glxK AMO57288.1 AMO57288.1 thiM thiM urk urk tdk tdk slyX slyX ppnK ppnK lpxK lpxK lysC lysC luxQ luxQ dhoM dhoM bvgS bvgS ndk ndk cysNC cysNC AMO55774.1 AMO55774.1 coaE coaE ribF ribF proB proB AMO55542.1 AMO55542.1 AMO55537.1 AMO55537.1 ahk ahk cpxA cpxA prkA1 prkA1 fruK fruK anmK anmK ackA ackA AMO55203.1 AMO55203.1 AMO55182.1 AMO55182.1 todS todS pfkA1 pfkA1 AMO55122.1 AMO55122.1 AMO55119.1 AMO55119.1 glk glk fucK fucK araB1 araB1 selD1 selD1 pdxK pdxK AMO54863.1 AMO54863.1 AMO54803.1 AMO54803.1 AMO54790.1 AMO54790.1 rdoA rdoA AMO54716.1 AMO54716.1 AMO54715.1 AMO54715.1 AMO54703.1 AMO54703.1 algZ algZ pilL pilL pgk pgk nagE1 nagE1 nagC nagC fixL fixL kguA kguA AMO54424.1 AMO54424.1 argB argB AMO54416.1 AMO54416.1 ptsI ptsI thrB2 thrB2 AMO57029.1 AMO57029.1 tmk2 tmk2 AMO56902.1 AMO56902.1 cmk cmk pyk pyk rsbW rsbW AMO56500.1 AMO56500.1 AMO56487.1 AMO56487.1 ppsA ppsA AMO56484.1 AMO56484.1 amt1 amt1 dck dck gsk gsk narX narX tmk1 tmk1 pyrH pyrH AMO56108.1 AMO56108.1 ppk ppk cbrA cbrA AMO58620.1 AMO58620.1 folK2 folK2 galK galK thiD thiD phoQ phoQ coaX coaX glnL glnL dhaL dhaL dhaK dhaK glpK glpK selD2 selD2 AMO58367.1 AMO58367.1 thiL thiL pk2 pk2 folK1 folK1 araB3 araB3 rstB rstB adk adk AMO57940.1 AMO57940.1 kdtA kdtA gmhC gmhC AMO57904.1 AMO57904.1 ubiB ubiB aroK aroK AMO57834.1 AMO57834.1 AMO57816.1 AMO57816.1 ispE ispE prpS prpS arcC3 arcC3 nagK nagK pt1_2 pt1_2 AMO57611.1 AMO57611.1 nagE3 nagE3 ptgCB3 ptgCB3 nagE2 nagE2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
prkA2Serine protein kinase PrkA. (640 aa)
phoRPhosphate regulon sensor histidine kinase, Classic. (437 aa)
pk1Pyruvate kinase; Belongs to the pyruvate kinase family. (478 aa)
pfkA26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (326 aa)
ptgCB2PTS system glucose-specific transporter subunit IIBC. (476 aa)
arcC2Carbamate kinase. (336 aa)
AMO57467.1Serine/threonine protein kinase. (525 aa)
AMO57466.1Serine/threonine protein kinase. (511 aa)
AMO57436.1Serine/threonine protein kinase catalytic subunit. (453 aa)
aceKBifunctional isocitrate dehydrogenase kinase/phosphatase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (587 aa)
arcC1Carbamate kinase; Belongs to the carbamate kinase family. (321 aa)
glxKGlycerate kinase; Belongs to the glycerate kinase type-1 family. (380 aa)
AMO57288.1Hypothetical protein. (130 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (266 aa)
urkUridine kinase. (206 aa)
tdkThymidine kinase. (193 aa)
slyXSlyX protein; Belongs to the SlyX family. (67 aa)
ppnKNAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (297 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (358 aa)
lysCAspartate kinase; Belongs to the aspartokinase family. (413 aa)
luxQMulti-sensor hybrid histidine kinase. (1096 aa)
dhoMHomoserine dehydrogenase. (433 aa)
bvgSSensor histidine kinase. (1161 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (143 aa)
cysNCBifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (634 aa)
AMO55774.1Serine/threonine protein kinase. (487 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (200 aa)
ribFBifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (311 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (375 aa)
AMO55542.1IS1595 family transposase. (158 aa)
AMO55537.1IS1595 family transposase. (185 aa)
ahkIntegral membrane sensor signal transduction histidine kinase. (656 aa)
cpxASensor histidine kinase. (464 aa)
prkA1Serine protein kinase PrkA. (640 aa)
fruK1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (319 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (364 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
AMO55203.1Two-component sensor kinase. (584 aa)
AMO55182.1Sensory transduction histidine kinase. (134 aa)
todSMulti-sensor signal transduction histidine kinase. (524 aa)
pfkA16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (421 aa)
AMO55122.1Response regulator/sensory box. (444 aa)
AMO55119.1Sensor histidine kinase. (1400 aa)
glkGlucokinase; Belongs to the bacterial glucokinase family. (315 aa)
fucKL-fuculokinase; Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family. (472 aa)
araB1Carbohydrate kinase. (529 aa)
selD1Selenide water dikinase; Synthesizes selenophosphate from selenide and ATP. (349 aa)
pdxKPyridoxal kinase; Belongs to the pyridoxine kinase family. (286 aa)
AMO54863.1Two component system sensor histidine kinase. (449 aa)
AMO54803.1Putative ATPase. (192 aa)
AMO54790.1Sensory box histidine kinase/response regulator. (936 aa)
rdoASerine/threonine protein kinase; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (336 aa)
AMO54716.1Lipopolysaccharide kinase. (251 aa)
AMO54715.1Mn2+dependent serine/threonine protein kinase. (327 aa)
AMO54703.1Mn2+-dependent serine/threonine protein kinase. (252 aa)
algZHistidine kinase internal region. (361 aa)
pilLType IV pili sensor histidine kinase and response regulator. (1980 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (387 aa)
nagE1PTS system N-acetylglucosamine-specific EIICBA component. (456 aa)
nagCN-acetylglucosamine-6P-responsive transcriptional repressor NagC. (400 aa)
fixLDiguanylate cyclase. (595 aa)
kguAGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (205 aa)
AMO54424.1Shikimate kinase. (198 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (312 aa)
AMO54416.1Hypothetical protein. (1090 aa)
ptsIPhosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (569 aa)
thrB2Homoserine kinase type II; Belongs to the pseudomonas-type ThrB family. (327 aa)
AMO57029.1Hypothetical protein; Belongs to the UPF0434 family. (70 aa)
tmk2Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (217 aa)
AMO56902.1Multi-sensor hybrid histidine kinase. (1970 aa)
cmkCytidylate kinase. (250 aa)
pykPyruvate kinase. (630 aa)
rsbWHistidine kinase. (147 aa)
AMO56500.1ATP-binding region, ATPase-like protein. (204 aa)
AMO56487.1Signal transduction histidine kinase. (488 aa)
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (800 aa)
AMO56484.1Hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (273 aa)
amt1Ammonium transporter. (686 aa)
dckDeoxynucleoside kinase. (208 aa)
gskInosine kinase. (432 aa)
narXNitrate/nitrite sensor protein NarX. (601 aa)
tmk1Thymidylate kinase. (191 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (245 aa)
AMO56108.1Hypothetical protein. (80 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (731 aa)
cbrATwo-component sensor CbrA. (1016 aa)
AMO58620.1Nitrous oxide-stimulated protein. (142 aa)
folK22-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (169 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (380 aa)
thiDHydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (277 aa)
phoQProtein PhoQ. (449 aa)
coaXBaf family transcriptional acitvator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (254 aa)
glnLTwo-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL. (348 aa)
dhaLDihydroxyacetone kinase, C-terminal domain. (215 aa)
dhaKDihydroxyacetone kinase, N-terminal domain. (333 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (502 aa)
selD2Selenide water dikinase; Synthesizes selenophosphate from selenide and ATP. (349 aa)
AMO58367.1Response regulator. (410 aa)
thiLThiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (322 aa)
pk2Pyruvate kinase; Belongs to the pyruvate kinase family. (473 aa)
folK12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (147 aa)
araB3Carbohydrate kinase. (528 aa)
rstBTwo-component system, OmpR family, sensor histidine kinase RstB. (529 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa)
AMO57940.1NagC/XylR family transcriptional regulator. (417 aa)
kdtA3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (433 aa)
gmhCBifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (481 aa)
AMO57904.1Hypothetical protein. (221 aa)
ubiB2-octaprenylphenol hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (533 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (174 aa)
AMO57834.1Hpt domain-containing protein. (108 aa)
AMO57816.1Hypothetical protein. (502 aa)
ispE4-diphosphocytidyl-2-methyl-D-erythritol synthase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (307 aa)
prpSRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa)
arcC3Carbamate kinase; Belongs to the carbamate kinase family. (311 aa)
nagKN-acetylglucosamine kinase. (301 aa)
pt1_2Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (571 aa)
AMO57611.1Integral membrane sensor signal transduction histidine kinase. (514 aa)
nagE3PTS system N-acetylglucosamine-specific transporter subunit IIBC. (484 aa)
ptgCB3PTS system glucose-specific transporter subunit IIBC. (483 aa)
nagE2PTS system N-acetylglucosamine-specific transporter subunit IIBC. (459 aa)
Your Current Organism:
Endozoicomonas montiporae
NCBI taxonomy Id: 570277
Other names: E. montiporae CL-33, Endozoicomonas montiporae CL-33, Endozoicomonas montiporae str. CL-33, Endozoicomonas montiporae strain CL-33, Endozoicomonas sp. CL-33
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