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dhaK_1 dhaK_1 aspA aspA cutC-2 cutC-2 gabD1 gabD1 gabD gabD gldA_1 gldA_1 pgm pgm galM galM galK galK AKL37389.1 AKL37389.1 galE galE AKL37303.1 AKL37303.1 yccU yccU pflD pflD AKL36794.1 AKL36794.1 gdhA_1 gdhA_1 AKL36146.1 AKL36146.1 ackA_2 ackA_2 pta pta eutD eutD yffB yffB AKL34776.1 AKL34776.1 fucA fucA fucI fucI fucK fucK AKL34687.1 AKL34687.1 AKL34661.1 AKL34661.1 pduW pduW AKL34501.1 AKL34501.1 gldA-2 gldA-2 gldA gldA AKL34004.1 AKL34004.1 dhaK dhaK dhaL dhaL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dhaK_1With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
aspAAspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
cutC-2Formate acetyltransferase; Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde. Belongs to the glycyl radical enzyme (GRE) family. CutC subfamily. (1128 aa)
gabD1Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
gabDSuccinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
gldA_1Oxidoreductase; Member of the iron-containing alcohol dehydrogenase family; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
pgmPhosphoglucomutase; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (546 aa)
galMGalactose-1-epimerase; Converts alpha-aldose to the beta-anomer. (347 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (382 aa)
AKL37389.1Galactose-1-phosphate uridylyltransferase; Catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (348 aa)
galEUDP-galactose-4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
AKL37303.1Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (810 aa)
yccUHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
pflDFormate acetyltransferase; Involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (765 aa)
AKL36794.1Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa)
gdhA_1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (424 aa)
AKL36146.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
ackA_2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
ptaPhosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (714 aa)
eutDPhosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
yffBReductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (117 aa)
AKL34776.11,2-propanediol oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
fucAFuculose phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. (215 aa)
fucISugar isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (591 aa)
fucKL-fuculose kinase; Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family. (472 aa)
AKL34687.1Sirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (264 aa)
AKL34661.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
pduWAcetate kinase; Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
AKL34501.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (714 aa)
gldA-2Glycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
gldAGlycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
AKL34004.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa)
dhaKDihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
dhaLDihydroxyacetone kinase; With DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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