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dhaL dhaL dhaK_1 dhaK_1 gldA-2 gldA-2 glnE glnE yqhD_1 yqhD_1 AKL34483.1 AKL34483.1 AKL38772.1 AKL38772.1 pduW pduW AKL34661.1 AKL34661.1 aldB_1 aldB_1 eutD eutD AKL35145.1 AKL35145.1 pta pta ackA_2 ackA_2 AKL35935.1 AKL35935.1 budA budA tyrS tyrS ldh ldh AKL36282.1 AKL36282.1 aldA aldA puuC puuC mgsA mgsA gldA_1 gldA_1 gldA gldA ascG_1 ascG_1 pyrE pyrE dhaK dhaK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dhaLDihydroxyacetone kinase; With DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
dhaK_1With DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
gldA-2Glycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
glnEBifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...] (944 aa)
yqhD_1Aldehyde reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
AKL34483.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (489 aa)
AKL38772.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
pduWAcetate kinase; Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
AKL34661.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
aldB_1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (506 aa)
eutDPhosphotransacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
AKL35145.1Aldehyde dehydrogenase; Ethanolamine utilization protein; catalyzes the formation of acetyl-CoA from acetaldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
ptaPhosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (714 aa)
ackA_2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
AKL35935.1Acetoin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (256 aa)
budAAlpha-acetolactate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the alpha-acetolactate decarboxylase family. (259 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (424 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (314 aa)
AKL36282.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (499 aa)
aldAAldehyde dehydrogenase; NAD-linked; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (479 aa)
puuCAldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (495 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (152 aa)
gldA_1Oxidoreductase; Member of the iron-containing alcohol dehydrogenase family; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
gldAGlycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
ascG_1LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa)
dhaKDihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
Your Current Organism:
Klebsiella oxytoca
NCBI taxonomy Id: 571
Other names: ATCC 13182, Bacillus oxytocus perniciosus, CCUG 15717, CIP 103434, DSM 5175, IAM 14201, K. oxytoca, Klebsiella sp. CECRI-24/07, Klebsiella sp. MN9SED2, LMG 3055, LMG:3055, NBRC 102593, NBRC 105695, NCTC 13727, strain 479-2
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